KEGG ORTHOLOGY: K18169

ORTHOLOGY: K18169

Entry

K18169                      KO

Symbol

TTC19

Name

tetratricopeptide repeat protein 19, mitochondrial

Disease

H02086

Mitochondrial complex III deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K18169  TTC19; tetratricopeptide repeat protein 19, mitochondrial
Mitochondrial biogenesis [BR:ko03029]
Mitochondrial quality control factors
  Mitochondrial respiratory chain complex assembly factors
   Complex-III assembly factors
    K18169  TTC19; tetratricopeptide repeat protein 19, mitochondrial

Genes

HSA:	54902(TTC19)

PTR:	455011(TTC19)

PPS:	100992903(TTC19)

GGO:	101147464(TTC19)

PON:	100451545(TTC19)

NLE:	100600031(TTC19)

HMH:	116463820 116463828

MCC:	700653(TTC19)

MCF:	102123085(TTC19)

MTHB:

126938807

MNI:	105491086(TTC19)

CSAB:

103242455(TTC19)

CATY:

105571939(TTC19)

PANU:

101004993(TTC19)

TGE:	112609888(TTC19)

MLEU:

105535989(TTC19)

RRO:	104681439(TTC19)

RBB:	108522163(TTC19)

TFN:	117066418(TTC19)

PTEH:

111526449(TTC19)

CANG:

105523185(TTC19)

CJC:	100387610(TTC19)

SBQ:	101041117(TTC19)

CIMI:

108281294(TTC19)

CSYR:

103264904(TTC19)

MMUR:

105856311(TTC19)

LCAT:

123650567(TTC19)

PCOQ:

105816110(TTC19)

OGA:	100944727(TTC19)

MMU:	72795(Ttc19)

MCAL:

110305305(Ttc19)

MPAH:

110331666(Ttc19)

RNO:	691506(Ttc19)

MCOC:

116076777(Ttc19)

ANU:	117712011(Ttc19)

MUN:	110549786(Ttc19)

CGE:	100760541(Ttc19)

MAUA:

101832000(Ttc19)

PROB:

127219154(Ttc19)

PLEU:

114682965(Ttc19)

MORG:

121456053(Ttc19)

MFOT:

126514640

AAMP:

119811150(Ttc19)

NGI:	103726233(Ttc19)

HGL:	101708781(Ttc19)

CPOC:

100721871(Ttc19)

CCAN:

109692525 109699490

DORD:

105985719(Ttc19)

DSP:	122101624(Ttc19)

PLOP:

125366193(Ttc19)

NCAR:

124980872

MMMA:

107160167(Ttc19)

OCU:

100354061

OPI:	101517457(TTC19)

TUP:	102485334(TTC19)

GVR:	103588965(TTC19)

CFA:	479516(TTC19)

CLUD:

112647294(TTC19)

VVP:	112924931(TTC19)

VLG:	121499504(TTC19)

NPO:	129496985(TTC19)

AML:	100480931(TTC19)

UMR:	103658514(TTC19)

UAH:	113271258(TTC19)

UAR:	123779777(TTC19)

ELK:	111139479 111139482

LLV:

125088140

MPUF:

101679670(TTC19)

MNP:	132003951(TTC19)

MLK:	131816859(TTC19)

NVS:	122906800(TTC19)

ORO:	101373133(TTC19)

EJU:	114198175(TTC19)

ZCA:	113939422(TTC19)

MLX:	118000113(TTC19)

NSU:	110584466(TTC19)

LWW:	102731668(TTC19)

FCA:	101083219(TTC19)

PYU:	121015845(TTC19)

PCOO:

112857109(TTC19)

PBG:	122485006(TTC19)

PVIV:

125151672(TTC19)

LRUF:

124519630

PTG:	102951492(TTC19)

PPAD:

109245812(TTC19)

PUC:

125927568

AJU:

106981420

HHV:	120228752(TTC19)

BTA:	789903(TTC19)

BOM:	102276871(TTC19)

BIU:	109573400(TTC19)

BBUB:

102404954(TTC19)

BBIS:

104990688(TTC19)

CHX:	102188348(TTC19)

OAS:	101107453(TTC19)

BTAX:

128065086(TTC19)

ODA:	120867422(TTC19)

CCAD:

122444697(TTC19)

MBEZ:

129544186(TTC19)

SSC:	102165221(TTC19)

CFR:	102517939(TTC19)

CBAI:

105084025(TTC19)

CDK:	105085084(TTC19)

VPC:	102544012(TTC19)

BACU:

103020763(TTC19)

BMUS:

118886153(TTC19) 118895986

LVE:	103081968(TTC19)

OOR:	101271080 101274573(TTC19)

DLE:	111167744(TTC19)

PCAD:

102982752(TTC19) 102992474

PSIU:

116745443(TTC19) 116753989

NASI:

112405197(TTC19)

ECB:	100073148(TTC19)

EPZ:	103560477(TTC19)

EAI:	106838860(TTC19)

MYB:	102248942(TTC19)

MYD:	102767190(TTC19)

MMYO:

118649375(TTC19)

MLF:	102433618(TTC19)

PKL:	118704689(TTC19)

EFUS:

103299373(TTC19)

MNA:	107524506(TTC19)

DRO:	112308481(TTC19)

SHON:

119002795(TTC19)

AJM:	119064422(TTC19)

PDIC:

114515018(TTC19)

PHAS:

123809295(TTC19)

MMF:	118641239(TTC19)

PPAM:

129068778(TTC19)

HAI:	109382178(TTC19)

RFQ:	117013487(TTC19)

PALE:

102894559(TTC19)

PGIG:

120589816(TTC19)

PVP:	105291303(TTC19)

RAY:	107511057(TTC19)

MJV:	108403988(TTC19)

TOD:	119232475(TTC19)

SARA:

101554951(TTC19)

SETR:

126013724(TTC19)

LAV:	100674561(TTC19)

TMU:

101346908

ETF:	101658585(TTC19) 101660345

DNM:	101428623(TTC19)

MDO:	100021098(TTC19)

GAS:	123244499(TTC19)

SHR:	100914060(TTC19)

AFZ:

127558773

PCW:	110222169(TTC19)

OAA:	100078193(TTC19)

GGA:	417597(TTC19)

PCOC:

116228021(TTC19)

MGP:	100546117(TTC19)

CJO:	107322413(TTC19)

TPAI:

128083591(TTC19)

LMUT:

125703144(TTC19)

NMEL:

110407642(TTC19)

APLA:

101799684(TTC19)

ACYG:

106045791(TTC19)

CATA:

118255063(TTC19)

AFUL:

116497162(TTC19)

TGU:	100224262(TTC19)

LSR:	110467692(TTC19)

SCAN:

103820147(TTC19)

PMOA:

120507610(TTC19)

OTC:	121345885(TTC19)

PRUF:

121361608(TTC19)

GFR:	102038169(TTC19)

FAB:	101806642(TTC19)

OMA:	130260899(TTC19)

PHI:	102106994(TTC19)

PMAJ:

107212776(TTC19)

CCAE:

111937796(TTC19)

CCW:	104691181(TTC19)

ETL:	114061258(TTC19)

ZAB:	102071365(TTC19)

ACHL:

103810685(TTC19)

SVG:	106853306(TTC19)

MMEA:

130576949(TTC19)

HRT:	120761508(TTC19)

FPG:	101912462(TTC19)

FCH:	102047352(TTC19)

CLV:	102095940(TTC19)

EGZ:	104121907(TTC19)

NNI:	104012184(TTC19)

PCRI:

104038848(TTC19)

PLET:

104624519(TTC19)

EHS:	104504508(TTC19)

PCAO:

104041572(TTC19)

ACUN:

113487113(TTC19)

TALA:

104366678(TTC19)

PADL:

103920798(TTC19)

AFOR:

103897989(TTC19)

ACHC:

115346871(TTC19)

HALD:

104313503(TTC19)

HLE:	104835616(TTC19)

AGEN:

126039975

GCL:

127024449

CCRI:

104155514(TTC19)

CSTI:

104553769(TTC19)

CMAC:

104473991(TTC19)

MUI:	104548287(TTC19)

BREG:

104633506(TTC19)

FGA:	104080823(TTC19)

GSTE:

104251409(TTC19)

LDI:	104350358(TTC19)

MNB:	103772759(TTC19)

OHA:	104339610(TTC19)

NNT:	104413345(TTC19)

SHAB:

115601988(TTC19)

DPUB:

104302738(TTC19)

PGUU:

104459430(TTC19)

ACAR:

104531040(TTC19)

CPEA:

104384825(TTC19)

AVIT:

104277517(TTC19)

CVF:	104284416(TTC19)

RTD:	128912797(TTC19)

CUCA:

104057147(TTC19)

TEO:	104372684(TTC19)

BRHI:

104493975(TTC19)

AAM:	106493738(TTC19)

AROW:

112960663(TTC19)

NPD:	112945416(TTC19)

TGT:	104572415(TTC19)

DNE:	112983935(TTC19)

SCAM:

104142844(TTC19)

ASN:	102368153(TTC19)

AMJ:	102564630(TTC19)

CPOO:

109317219(TTC19)

GGN:	109293156(TTC19)

PSS:	102449105(TTC19)

CMY:	102936349(TTC19)

CCAY:

125623769(TTC19)

DCC:	119844865(TTC19)

CPIC:

101950130(TTC19)

TST:	117867364(TTC19)

CABI:

116827138(TTC19)

MRV:	120387232(TTC19)

ACS:	100555831(ttc19)

ASAO:

132763409(TTC19)

PVT:	110087393(TTC19)

SUND:

121917141(TTC19)

PBI:	103050480(TTC19)

PMUR:

107284466(TTC19)

CTIG:

120318838(TTC19)

TSR:	106553716(TTC19)

APRI:

131188622(TTC19)

VKO:	123023578(TTC19)

PMUA:

114585196(TTC19)

PRAF:

128403043(TTC19)

ZVI:	118097121(TTC19)

HCG:	128336200(TTC19)

GJA:	107119550(TTC19)

STOW:

125445568(TTC19)

EMC:	129345037(TTC19)

XLA:	108709194(ttc19.S)

XTR:	100485992(ttc19)

NPR:	108790713(TTC19)

RTEM:

120927734(TTC19)

BBUF:

120994648(TTC19)

BGAR:

122930394(TTC19)

MUO:	115456710(TTC19)

GSH:	117349028(TTC19)

DRE:	564788(ttc19)

SRX:	107709862(ttc19) 107718030

SANH:

107657437(ttc19)

SGH:	107599873(ttc19)

CCAR:

109062035 109106843

CAUA:

113045690(ttc19)

CGIB:

127950715 128021638

PTET:

122357231(ttc19)

LROH:

127178701(ttc19)

OMC:	131524277(ttc19)

PPRM:

120482153(ttc19)

RKG:	130101720(ttc19)

MAMB:

125251164(ttc19)

CIDE:

127502480

MASI:

127441432 127442142

TROS:

130555002(ttc19)

TDW:	130417677(ttc19)

MANU:

129442061(ttc19)

IPU:

108267676

IFU:	128609565(ttc19)

PHYP:

113540170(ttc19)

SMEO:

124388108(ttc19)

TFD:	113657639(ttc19)

TVC:	132848378(ttc19)

AMEX:

103041539(ttc19)

CMAO:

118826426(ttc19)

EEE:	113590311(ttc19)

CHAR:

105891348(ttc19)

TRU:	101061165(ttc19)

TFS:	130539149(ttc19)

TBEN:

117483667(ttc19)

EMAC:

134866387(ttc19)

ELY:	117271423(ttc19)

SLUC:

116037204(ttc19)

PFLV:

114565519(ttc19)

GAT:	120816509(ttc19)

PPUG:

119209132(ttc19)

AFB:	129116752(ttc19)

CLUM:

117747033(ttc19)

MSAM:

119894585 119902751

SCHU:

122886863(ttc19)

CUD:

121520286

ALAT:

119011571(ttc19)

MZE:	101473505(ttc19)

ONL:	100691956(ttc19)

OAU:	116321295(ttc19)

OLA:	101167484(ttc19)

OML:	112144347(ttc19)

CSAI:

133452959(ttc19)

XMA:	102236539(ttc19)

XCO:	114146148(ttc19)

XHE:	116721445(ttc19)

PRET:

103460495(ttc19)

PFOR:

103129936(ttc19)

PLAI:

106941979(ttc19)

PMEI:

106907561(ttc19)

GAF:	122841610(ttc19)

PPRL:

129356711

CVG:	107104356(ttc19)

CTUL:

119776809(ttc19)

GMU:	124869314(ttc19)

NFU:	107383402(ttc19)

ALIM:

106534224(ttc19)

NWH:	119414829(ttc19) 119426817

AOCE:

111577610 111587510

MCEP:

125010378(ttc19)

CSEM:

103398720(ttc19)

POV:	109645504(ttc19)

SSEN:

122769942(ttc19)

HHIP:

117777852(ttc19)

HSP:	118117469(ttc19)

SMAU:

118311112(ttc19)

LCF:

108884935

SDU:	111237339(ttc19)

SLAL:

111659181(ttc19)

XGL:	120800867(ttc19)

HCQ:	109518913(ttc19)

SSCV:

125985453

SBIA:

133510622(ttc19)

PEE:	133411495(ttc19)

PTAO:

133489472(ttc19)

BPEC:

110170955(ttc19)

MALB:

109974843(ttc19)

BSPL:

114844243(ttc19)

SJO:	128368621(ttc19)

SASA:

106568661 106597187

STRU:

115156565 115170151

OTW:	112227237 112260148

OMY:	110509092 110529968

OGO:	124010240 124042149(ttc19)

ONE:	115103376 115114081(ttc19)

OKI:	109872037 109875215(ttc19)

OKE:	118394404 118402446(ttc19)

SALP:

111957144(ttc19) 111979539

SNH:	120020715 120055706(ttc19)

CCLU:

121534921 121580601

ELS:	105025000(ttc19)

SFM:	108937694(ttc19)

PKI:	111837196(ttc19)

AANG:

118234104(ttc19)

LOC:	102694755(ttc19)

PSPA:

121314395(ttc19)

ARUT:

117435790(ttc19)

PSEX:

120529434(ttc19)

LCM:	102360255(TTC19)

CMK:	103190506(ttc19)

CPLA:

122548804(ttc19)

HOC:	132815135(ttc19)

LERI:

129696403(ttc19)

PMRN:

116941033(TTC19)

LRJ:	133344785(TTC19)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

SKO:

DME:	Dmel_CG15173(Ttc19)

DER:

6549441

DSE:

6614634

DSI:	Dsimw501_GD21786(Dsim_GD21786)

DYA:	Dyak_GE12679

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI17348

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ008085

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:	109534937 109540357

SOY:	115875379 115876363

AGRG:

126744135

ATD:

109605740

CSET:

123309506 123309507 123311541

AGB:	108909332 108911748

LDC:	111514305 111515035

NVL:	108560143 108564358

APLN:

108740114

PPYR:

116170499 116170664

OTU:	111414052 111424808

BMOR:

101743207

BMAN:

114244120

MSEX:

115452416

DPL:	KGM_214014

BANY:

MJU:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

ZCE:	119832088 119832091

LSIN:

AAGE:

HAW:

HZE:

TNL:	113495497 113504769 113507556

SLIU:

OFU:

PXY:

PGW:

CCRN:

API:	100162514 100575884

DNX:	107164518 107173667

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106678464 106678608 106680231

NLU:

111055217

HVI:

124364904

MQU:

128999768

PHU:	Phum_PHUM137850 Phum_PHUM463510

FOC:

TPAL:

ZNE:

CSEC:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_59427

DMK:	116916172 123467585

DPZ:

PVM:

PJA:

PCHN:

PMOO:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:	107366708 107366792

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

PMEO:

CEL:	CELE_Y54G11A.8(ddl-3)

CBR:	CBG_11100(Cbr-ddl-3)

CRQ:	GCK72_004675

NAI:	NECAME_08421

BMY:	BM_BM6830(Bma-ddl-3)

LOA:	LOAG_08329

TSP:

Tsp_08471

LGI:	LOTGIDRAFT_132697

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:	111125731 111125869

CANU:

128157030

OED:

125679050

MYI:	110441243 110449924

PMAX:

MMER:

RPHI:

OBI:

OSN:

LAK:

SMM:	Smp_076910

SHX:	MS3_00004673(TTC19)

EGL:

NVE:

EPA:

ATEN:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_54077

AQU:

105314559

» show all

Reference

PMID:21278747

Authors

Ghezzi D, Arzuffi P, Zordan M, Da Re C, Lamperti C, Benna C, D'Adamo P, Diodato D, Costa R, Mariotti C, Uziel G, Smiderle C, Zeviani M

Title

Mutations in TTC19 cause mitochondrial complex III deficiency and neurological impairment in humans and flies.

Journal

Nat Genet 43:259-63 (2011)
DOI:10.1038/ng.761

Sequence

[hsa:54902] [dme:Dmel_CG15173]

LinkDB

DBGET integrated database retrieval system