ORTHOLOGY: K18290
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Entry
K18290 KO
Symbol
ich-Y
Name
itaconyl-CoA hydratase [EC:
4.2.1.56
]
Pathway
map00660
C5-Branched dibasic acid metabolism
map01100
Metabolic pathways
Reaction
R02491
(3S)-citramalyl-CoA hydro-lyase (itaconyl-CoA-forming)
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
K18290 ich-Y; itaconyl-CoA hydratase
Enzymes [BR:
ko01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.56 itaconyl-CoA hydratase
K18290 ich-Y; itaconyl-CoA hydratase
BRITE hierarchy
Other DBs
COG:
COG2030
GO:
0050011
Genes
STM:
STM3119
SEO:
STM14_3768
SEV:
STMMW_30791
SEY:
SL1344_3093
SEM:
STMDT12_C31720
SEJ:
STMUK_3107
SEB:
STM474_3268
SEF:
UMN798_3389
SETU:
STU288_15785
SETC:
CFSAN001921_01430
SENR:
STMDT2_30131
SEND:
DT104_31151
SENI:
CY43_16260
SEEN:
SE451236_21710
SPQ:
SPAB_03889
SEI:
SPC_3186
SEC:
SCH_3059
(maoC)
SEH:
SeHA_C3361
SHB:
SU5_03617
SENH:
CFSAN002069_16555
SEEH:
SEEH1578_01720
SEE:
SNSL254_A3368
SENN:
SN31241_42430
SEW:
SeSA_A3294
SED:
SeD_A3463
SEG:
SG3013
SEL:
SPUL_3122
SEGA:
SPUCDC_3108
SET:
SEN2962
SENA:
AU38_15055
SENO:
AU37_15065
SENV:
AU39_15060
SENQ:
AU40_16975
SENL:
IY59_15665
SENJ:
CFSAN001992_17980
SEEB:
SEEB0189_004285
SEEP:
I137_14920
SENB:
BN855_31910
SENE:
IA1_15055
SES:
SARI_04512
SALZ:
EOS98_03725
YPE:
YPO1927
YPK:
y2384
YPA:
YPA_1305
YPM:
YP_1669
(maoC)
YPP:
YPDSF_1197
YPG:
YpAngola_A2117
YPD:
YPD4_1694
YPX:
YPD8_1854
YPW:
CH59_3723
YPV:
BZ15_1615
YPL:
CH46_3188
YPS:
YPTB1925
YPO:
BZ17_546
YPI:
YpsIP31758_2157
YPY:
YPK_2267
YPB:
YPTS_1974
YPQ:
DJ40_390
YPU:
BZ21_1196
YPR:
BZ20_193
YPC:
BZ23_1479
YPF:
BZ19_1271
YSI:
BF17_18435
SPE:
Spro_3023
SLQ:
M495_15430
SQU:
E4343_00900
SENP:
KHA73_09775
(ripB)
SGRI:
SGBXF1_03031
(paaZ_1)
SOD:
Sant_0822
XHO:
A9255_04215
STEK:
AXG53_18865
LCIC:
INQ41_12735
LAVI:
INQ42_12365
PFN:
HZ99_04650
PMUD:
NCTC8068_02061
(phaJ_1)
PPUU:
PputUW4_01806
PFK:
PFAS1_01245
PSEJ:
HNQ25_04425
PIE:
HU724_013970
PSTT:
CH92_21350
HPEG:
EAO82_03715
THT:
E2K93_09365
TPSY:
RGQ13_18710
GAG:
Glaag_1578
PMES:
FX988_04170
PAT:
Patl_2716
MICC:
AUP74_02898
(paaZ)
MAGA:
Mag101_09735
MII:
BTJ40_11590
MICT:
FIU95_07925
MHYD:
GTQ55_10130
MVB:
MJO52_13465
MPAF:
R5R33_01630
MICY:
HUW35_16885
HALC:
EY643_14920
CBU:
CBU_0373
CBS:
COXBURSA331_A0480
CBD:
CBUD_1709
CBG:
CbuG_1636
CBC:
CbuK_0564
LLO:
LLO_3026
LSH:
CAB17_01570
LCJ:
NCTC11976_03021
TMC:
LMI_0900
FPZ:
LA55_828
FNA:
OOM_1390
FNL:
M973_04670
BMA:
BMAA1652
BMV:
BMASAVP1_1726
BML:
BMA10229_1932
BMN:
BMA10247_A0609
BMAZ:
BM44_3168
BMAL:
DM55_3232
BMAE:
DM78_4162
BMAQ:
DM76_3930
BMAI:
DM57_07715
BMAF:
DM51_3350
BMAB:
BM45_4007
BPS:
BPSS1638
BPM:
BURPS1710b_A0702
BPL:
BURPS1106A_A2221
BPD:
BURPS668_A2304
BPSE:
BDL_4991
BPSM:
BBQ_4503
BPSU:
BBN_5091
BPSD:
BBX_4157
BPZ:
BP1026B_II1752
BPQ:
BPC006_II2199
BPK:
BBK_4297
BPSH:
DR55_3632
BPSA:
BBU_4389
BPSO:
X996_5998
BUT:
X994_5470
BTD:
BTI_4119
BOK:
DM82_5766
BOC:
BG90_4867
BSAV:
WS86_27025
BHG:
I6G56_32450
BUD:
AQ610_22590
BYI:
BYI23_C008040
(maoC)
BUE:
BRPE67_CCDS03190
(maoC)
BUL:
BW21_6125
BUM:
AXG89_23910
AXG89_28780
AXG89_40395
BUI:
AX768_19490
BXE:
Bxe_A4088
BXB:
DR64_1764
BPY:
Bphyt_0612
PARB:
CJU94_03205
PTER:
C2L65_44455
PACS:
FAZ98_15395
PDIO:
PDMSB3_0446
PPK:
U875_11925
PPNO:
DA70_04325
PPNM:
LV28_01985
PRB:
X636_22780
PTX:
ABW99_05285
PAND:
DRB87_09750
DRB87_14365
PANN:
PanNE5_31350
PANX:
OYT13_14965
CABA:
SBC2_62820
(mch)
TVL:
FAZ95_35740
BPE:
BP0436
BPC:
BPTD_0451
BPER:
BN118_0287
BPET:
B1917_3383
BPEU:
Q425_33750
BPAR:
BN117_0456
BPA:
BPP0463
BBH:
BN112_2949
BBR:
BB0463
BBM:
BN115_0450
BBX:
BBS798_0460
BPT:
Bpet0844
BHO:
D560_0129
BHM:
D558_0125
BHZ:
ACR54_01121
(paaZ_1)
BOH:
AKI39_05280
POLL:
OEG81_02055
BOZ:
DBV39_05635
PARK:
LSG25_20015
RFR:
Rfer_4170
Rfer_4180
RHF:
EUB48_16960
POL:
Bpro_5294
CENP:
M9799_12210
ADN:
Alide_3398
ADK:
Alide2_1037
HYR:
BSY239_2753
HPSE:
HPF_13035
(paaZ2)
MNR:
ACZ75_13500
ACZ75_18265
XYK:
GT347_03980
APET:
ToN1_12320
BEB:
AEM42_06475
RLS:
HB780_13270
VGO:
GJW-30_1_01517
(paaZ_1)
XDI:
EZH22_28925
STAR:
G3545_21885
SNO:
Snov_3518
AQI:
J5J86_04975
BID:
Bind_2533
RHZ:
RHPLAN_27280
CMET:
K6K41_24180
(ripB)
RBM:
TEF_02360
PHR:
C6569_20835
ACUT:
MRB58_13920
CSE:
Cseg_2763
CFH:
C1707_19790
SPSE:
SULPSESMR1_04108
(mch)
HNE:
HNE_1098
HBC:
AEM38_15990
NGF:
FRF71_11070
NOG:
GKE62_07625
SPHM:
G432_00490
SPHI:
TS85_14845
SLAN:
GV829_06060
SAER:
NEF64_09100
SRAD:
LLW23_07945
SABI:
PBT88_13995
SFLA:
SPHFLASMR4Y_02130
(mch)
SPHY:
CHN51_04325
SPHL:
LPB140_01050
BLAS:
BSY18_2912
BSY18_3093
BFW:
B5J99_05640
B5J99_06505
PALG:
HFP57_14280
PARP:
HFP51_13365
PARJ:
J4G78_13065
PHAO:
HF685_09495
SMIC:
SmB9_17900
SFLV:
IC614_07675
SAND:
H3309_06830
ALH:
G6N82_04765
ANH:
A6F65_00044
(paaZ_1)
ADO:
A6F68_02606
(paaZ_3)
EGN:
BMF35_a1281
ELQ:
Ga0102493_11612
ERYT:
KDC96_11235
PHZ:
CHX26_06045
PORC:
CBR61_08750
SHUM:
STHU_28440
SVC:
STVA_32330
STEL:
STAQ_25590
ABS:
AZOBR_p460036
ABQ:
ABAZ39_31965
ABF:
AMK58_24905
AMK58_27770
AZT:
TSH58p_20920
AARE:
D3093_28145
NCB:
C0V82_13805
C0V82_17290
HADH:
FRZ61_45880
THAR:
T8K17_02695
TMO:
TMO_b0388
GEB:
GM18_3660
GER:
KP004_02745
GSUB:
KP001_12705
GNT:
KP003_02380
GPL:
M1B72_18220
MSD:
MYSTI_02518
MYSTI_04298
MYM:
A176_004230
MFB:
MFUL124B02_13435
MFUL124B02_23085
MYX:
QEG98_21665
MLAN:
JY572_05235
JY572_13775
MFU:
LILAB_26410
MMAS:
MYMAC_003593
PPAK:
JY651_16010
AGE:
AA314_08469
PARH:
I5S86_16400
OON:
NP440_17390
ASED:
IRT44_09900
HNZ:
P9989_10925
HSHI:
MUO14_08130
LEX:
Len3610_00575
RUE:
DT065_03735
SALE:
EPH95_03505
SCIB:
HUG20_10875
SCIA:
HUG15_13410
AHAL:
FTX54_001420
BCOP:
JD108_17245
BAYD:
BSPP4475_15625
ANEU:
PP175_10760
SIV:
SSIL_0090
SSIL:
SOLI23_18375
MTUY:
H3143_01770
MSY:
MS53_0536
MSO:
VY93_02915
MGA:
MGA_1305
(maoC)
MGH:
MGAH_1305
MGF:
MGF_3286
MIW:
EER00_03360
ERZ:
ER308_17470
MLP:
MLM_2703
MUL:
MUL_4022
MMI:
MMAR_4159
MMAE:
MMARE11_39690
MLI:
MULP_04327
MPSE:
MPSD_17120
MSHO:
MSHO_16380
MSAK:
MSAS_14220
MBAI:
MB901379_00390
(phaJ)
MSEO:
MSEO_43210
MLJ:
MLAC_39600
MGO:
AFA91_09670
MSTE:
MSTE_02642
CPU:
CPFRC_05850
CPL:
Cp3995_1184
CPG:
CP316_06000
CPP:
CpP54B96_1180
CPK:
CP1002_07295
CPQ:
CPC231_05855
CPX:
CPI19_05665
CPZ:
CpPAT10_1157
COR:
Cp267_1212
COP:
CP31_06230
COD:
Cp106_1142
COS:
Cp4202_1151
COI:
CPCIP5297_06015
COE:
CP258_06010
COU:
CP162_05280
CPSE:
CPTA_01733
CPSU:
CPTB_02030
CPSF:
CPTC_01724
CMD:
B841_00430
CAQU:
CAQU_08895
COK:
COCCU_01040
CFAC:
CFAEC_04130
(paaZ2)
NNO:
NONO_c35120
NOZ:
DMB37_03985
NIE:
KV110_07705
KV110_22130
ROA:
Pd630_LPD07625
RPY:
Y013_25540
RHB:
NY08_70
RHU:
A3Q40_00682
(mch_1)
RGOR:
NMQ04_21480
RHOO:
RA302_03040
RFA:
A3L23_03454
(mch)
RHS:
A3Q41_04802
(mch)
PSOW:
ABI214_15395
WHR:
OG579_10055
GTA:
BCM27_00330
GRU:
GCWB2_00255
GAV:
C5O27_04375
GOD:
GKZ92_00500
GOS:
QAD21_00290
GOJ:
GR168_00330
GHN:
MVF96_00300
GAMI:
IHQ52_03920
SRT:
Srot_1098
SCO:
SCP1.303
(sapE)
SGR:
SGR_558
SANL:
KZO11_35880
SRC:
M271_49660
SBH:
SBI_09088
STRM:
M444_14895
SCAD:
DN051_00530
DN051_40280
SNW:
BBN63_32945
SRJ:
SRO_1328
STIR:
DDW44_01555
SFIC:
EIZ62_01245
SSPO:
DDQ41_10335
SGF:
HEP81_01295
SBAT:
G4Z16_30040
SVD:
CP969_00525
SMOB:
J7W19_01990
SMAO:
CAG99_00030
SXT:
KPP03845_200131
(mch)
STUD:
STRTU_001462
SGK:
PET44_13710
SFIY:
F0344_13485
SLUO:
PS467_39505
SRPA:
HEP86_02135
KSK:
KSE_23690
KAB:
B7C62_13320
KAU:
B6264_30520
KIT:
CFP65_5905
STRI:
C7M71_005355
MSUW:
GCM10025863_19200
AMIN:
AUMI_115630
AUW:
AURUGA1_01431
(paaZ)
SUBA:
LQ955_13915
LQ955_17435
ARTP:
E5206_12360
ARTY:
AHiyo4_01850
POK:
SMD14_09280
BSPO:
L1F31_01260
NCA:
Noca_4064
NOI:
FCL41_07655
NFC:
KG111_04935
NOF:
MF408_05830
ADB:
NP095_13810
AWN:
NQV15_15565
MUZ:
H4N58_19260
AMAZ:
LUW76_46480
ACIR:
OG979_01530
SPIQ:
OHA34_28675
ACTQ:
OG417_30485
OG417_33635
SRO:
Sros_6336
NOA:
BKM31_26125
NGN:
LCN96_20470
NFS:
OIE67_25980
MHAI:
OHB01_26640
OHB01_36725
FAL:
FRAAL3417
SEN:
SACE_2330
AMYC:
CU254_42145
AORI:
SD37_10620
AACD:
LWP59_16160
LWP59_38895
ARHD:
VSH64_05575
AMOG:
QRX60_45590
ACOR:
LCL61_28770
ANW:
QP939_34740
PDX:
Psed_0099
Psed_4113
Psed_6732
PSEE:
FRP1_16985
PSEQ:
AD006_24435
PECQ:
AD017_04025
PHH:
AFB00_22120
PAUT:
Pdca_22270
PPEL:
H6H00_21480
ACTY:
OG774_11915
STP:
Strop_0462
Strop_1721
SAQ:
Sare_2919
MICH:
FJK98_21010
MCRA:
ID554_06815
VER:
HUT12_06145
MFEU:
H1D33_27590
MCAY:
PVK37_26025
AMS:
AMIS_57130
ACTL:
L3i22_079410
ASIC:
Q0Z83_062770
(ripB)
ACTE:
ACTI_81670
PLK:
CIK06_24305
PRY:
Prubr_51730
DFU:
Dfulv_32600
Dfulv_34310
DROS:
Drose_23805
DACT:
KZZ52_46990
RXY:
Rxyl_0670
Rxyl_2737
RRD:
RradSPS_1705
RUB:
GBA63_03935
BSOL:
FSW04_07165
SBAE:
DSM104329_05572
(mch_2)
LEPV:
J4558_03705
CALL:
OZ401_004534
PBF:
CFX0092_B0383
VAB:
WPS_02220
STI:
Sthe_1792
DTAE:
LAJ19_17235
TPSC:
RBB77_12700
(ripB)
ARAC:
E0W69_008615
HAL:
VNG_2290G
(maoC1)
HSL:
OE_4209F
(maoC1)
HANR:
LJ422_09245
HAGS:
JT689_10595
HABO:
JRZ79_08970
HSU:
HLASF_0426
HSF:
HLASA_0424
HAHS:
HSRCO_0071
(maoC)
SALR:
FQU85_08755
HJE:
HacjB3_13725
HALX:
M0R89_21420
HAYC:
NGM10_17940
NPH:
NP_0916A
(maoC4)
NHO:
HWV23_12055
NSAL:
HWV07_13725
HALI:
BV210_16875
SSAI:
N0B31_11010
HAQ:
DU484_05285
HAJ:
DU500_05725
HRA:
EI982_05240
HALB:
EKH57_10330
HALQ:
Hrr1229_005595
HSAI:
HPS36_05590
SRUB:
C2R22_10080
HALG:
HUG10_11570
HALU:
HUG12_00295
HUG12_04285
HMP:
K6T50_17560
HRE:
K6T36_16465
HAH:
Halar_0325
NMG:
Nmag_3455
NPE:
Natpe_1337
NVR:
FEJ81_07125
NAY:
HYG81_23810
HJT:
DVR14_15860
NGE:
Natgr_2181
HALV:
NGM15_18110
NOU:
Natoc_4274
NBG:
DV706_20325
DV706_21415
NAS:
GCU68_04235
GCU68_20760
HDA:
BB347_13355
» show all
Taxonomy
UniProt
Reference
PMID:
24657929
Authors
Sasikaran J, Ziemski M, Zadora PK, Fleig A, Berg IA
Title
Bacterial itaconate degradation promotes pathogenicity.
Journal
Nat Chem Biol 10:371-7 (2014)
DOI:
10.1038/nchembio.1482
Sequence
[ypk:
y2384
]
LinkDB
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DBGET
integrated database retrieval system