KEGG   ORTHOLOGY: K18782
Entry
K18782            Tight     KO                                     
Symbol
blaIMP
Name
metallo-beta-lactamase class B IMP [EC:3.5.2.6]
Pathway
map01501  beta-Lactam resistance
Module
M00851  Carbapenem resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    K18782  blaIMP; metallo-beta-lactamase class B IMP
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K18782  blaIMP; metallo-beta-lactamase class B IMP
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.6  beta-lactamase
     K18782  blaIMP; metallo-beta-lactamase class B IMP
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  beta-Lactamase genes
   Class B [MT]
    K18782  blaIMP; metallo-beta-lactamase class B IMP
Antimicrobial resistance: KEGG signatures [br01600.html]
 Signature KOs for antimicrobial resistance
  K18782
Other DBs
COG: COG0491
GO: 0008800
Genes
KPAS: LUW96_29395
KAS: KATP_49770(blaIMP-1)
METY: MRY16398_p20060(blaIMP-6)
PVJ: LMA04_21335
SMAR: SM39_pSMC1_38(blaIMP-1)
PRQ: CYG50_00315 CYG50_00715
PNC: NCGM2_1757(bla_IMP)
PAEB: NCGM1900_1412(blaIMP-34) NCGM1900_3685(blaIMP-34)
PJU: L1P09_25500
APRL: PY247_21710
AG: AAB30289(IMP-1) AAK12087(IMP-7) AAK13078(IMP-4) AAK13430(IMP-8) AAK27847(IMP-5) AAT49070(IMP-15) AAV49162(IMP-18) ABC88434(IMP-22) ABF70513(IMP-30) ABM67078(IMP-19) ABM68358(IMP-24) ACB41775(IMP-25) ACY01749(IMP-26) ADT63777(IMP-29) AEH41427(IMP-27) AEU17778(IMP-33) AFG73659(IMP-28) AFO59566(IMP-35) AFP97028(IMP-37) AGL46523(IMP-9) AGS82587(IMP-31) AIA58910(IMP-45) AOE46845(IMP-62) APM84539(IMP-65) BAA77393(IMP-3) BAB15941(IMP-6) BAB72069(IMP-10) BAM98935(IMP-43) BAM98942(IMP-44) BAP75826(IMP-34) CAB94707(IMP-2) CAD12765(IMP-12) CAD80251(IMP-13) CAE48334(IMP-16)
 » show all
Reference
PMID:8141584
  Authors
Osano E, Arakawa Y, Wacharotayankun R, Ohta M, Horii T, Ito H, Yoshimura F, Kato N
  Title
Molecular characterization of an enterobacterial metallo beta-lactamase found in a clinical isolate of Serratia marcescens that shows imipenem resistance.
  Journal
Antimicrob Agents Chemother 38:71-8 (1994)
DOI:10.1128/AAC.38.1.71
  Sequence
[ag:AAB30289]
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