KEGG ORTHOLOGY: K19361

ORTHOLOGY: K19361

Entry

K19361                      KO

Symbol

TCTN2

Name

tectonic-2

Disease

H00261

Meckel syndrome

H00530

Joubert syndrome and related disorders

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K19361  TCTN2; tectonic-2
Cilium and associated proteins [BR:ko03037]
Primary cilia and associated proteins
  MKS complex
   K19361  TCTN2; tectonic-2

Genes

HSA:	79867(TCTN2)

PTR:	100615573(TCTN2)

PPS:	100974621(TCTN2)

GGO:	101146235(TCTN2)

PON:	100454231(TCTN2)

PPYG:

129010415(TCTN2)

NLE:	100581318(TCTN2)

HMH:	116477725(TCTN2)

SSYN:

129460323(TCTN2)

MCC:	721415(TCTN2)

MCF:	102127899(TCTN2)

MTHB:

126930617

MNI:	105493893(TCTN2)

CSAB:

103239337(TCTN2)

CATY:

105591012(TCTN2)

PANU:

101014928(TCTN2)

TGE:	112634598(TCTN2)

MLEU:

105545848(TCTN2)

RRO:	104666366(TCTN2)

RBB:	108540648(TCTN2)

TFN:	117089208(TCTN2)

PTEH:

111538584(TCTN2)

CANG:

105516293(TCTN2)

CJC:	100896306(TCTN2)

SBQ:	101037751(TCTN2)

CIMI:

108315199(TCTN2)

ANAN:

105713401(TCTN2)

MMUR:

105880861(TCTN2)

LCAT:

123626126(TCTN2)

ERUF:

138401866(TCTN2)

PCOQ:

105825688(TCTN2)

OGA:	100956937(TCTN2)

MMU:	67978(Tctn2)

MCAL:

110294939(Tctn2)

MPAH:

110312937(Tctn2)

RNO:	689779(Tctn2)

MCOC:

116068439(Tctn2)

ANU:	143437807(Tctn2)

ASYL:

127673140(Tctn2)

MMIU:

308439554(TCTN2)

MUN:	110552680(Tctn2)

CGE:	100768551(Tctn2)

MAUA:

101835092(Tctn2)

PROB:

127236952(Tctn2)

PLEU:

114704509(Tctn2)

PMAV:

143270381(Tctn2)

MORG:

121446554(Tctn2)

MFOT:

126504314

AAMP:

119825524(Tctn2)

CNL:	130871173(Tctn2)

NGI:	103739022(Tctn2)

HGL:	101698943(Tctn2)

CPOC:

101787809(Tctn2)

CCAN:

109684878(Tctn2)

DORD:

105990609(Tctn2)

DSP:	122098532(Tctn2)

DMER:

138828751(Tctn2)

PLOP:

125349201(Tctn2)

NCAR:

124990220

SVUL:

306667742(TCTN2)

MMMA:

107156379(Tctn2)

ITI:	101971820(Tctn2)

SCIL:

308646000(TCTN2)

OCU:

103346105

OPI:	101517598(TCTN2)

OCZ:	121160929(TCTN2)

TUP:	102469987(TCTN2)

GVR:	103606948(TCTN2)

CFA:	477445(TCTN2)

CLUD:

112676453(TCTN2)

VVP:	112933820(TCTN2)

VLG:	121475859(TCTN2)

NPO:	129508198(TCTN2)

AML:	105238177(TCTN2)

UMR:	103661251(TCTN2)

UAH:	113266888(TCTN2)

UAR:	123779988(TCTN2)

ELK:

111156539

LLV:

125081903

MPUF:

101684795(TCTN2)

MNP:	132023084(TCTN2)

MLK:	131811371(TCTN2)

NVS:	122903079(TCTN2)

MMAQ:

308354366(TCTN2)

ORO:	101382686(TCTN2)

EJU:	114200370(TCTN2)

ZCA:	113912941(TCTN2)

MLX:	118018393(TCTN2)

MANO:

123853148(TCTN2)

NSU:	110588318(TCTN2)

LWW:	102735287(TCTN2)

FCA:	101085243(TCTN2)

PYU:	121010406(TCTN2)

PCOO:

112870289(TCTN2)

PBG:	122470139(TCTN2)

PVIV:

125149568(TCTN2)

LRUF:

124518171

LGF:	123588543(TCTN2)

AJU:

106978343

PTG:	102959363(TCTN2)

PPAD:

109277751(TCTN2)

PUC:

125914256

PLEZ:

122203804(TCTN2)

HHV:	120236642(TCTN2)

CCRU:

144218150(TCTN2)

BTA:	100847961(TCTN2)

BOM:	102266395(TCTN2)

BIU:	109571483(TCTN2)

BJV:	133228759(TCTN2)

BBUB:

102416029(TCTN2)

BKE:	129629985(TCTN2)

BBIS:

104989573(TCTN2)

CHX:	102180068(TCTN2)

OAS:	101121804(TCTN2)

OCAN:

138422566(TCTN2)

BTAX:

128062321(TCTN2)

CSUM:

138093553(TCTN2)

ODA:	120871038(TCTN2)

CCAD:

122424484(TCTN2)

MREE:

136146066(TCTN2)

OVR:	110142240(TCTN2)

MBEZ:

129542710(TCTN2)

SSC:	100153315(TCTN2)

CFR:	102522788(TCTN2)

CBAI:

105080671(TCTN2)

CDK:	105094333(TCTN2)

VPC:	107034084(TCTN2)

BACU:

103001875(TCTN2)

BMUS:

118906628(TCTN2)

LVE:	103074372(TCTN2)

OOR:	101276861(TCTN2)

LALB:

132532285(TCTN2)

GMF:	115855194(TCTN2)

DDP:	132436446(TCTN2)

SCOO:

307196833(TCTN2)

PCRS:

137203962(TCTN2)

DLE:	111186951(TCTN2)

PCAD:

102986238(TCTN2)

PSIU:

116738764(TCTN2)

PPHC:

136132656(TCTN2)

NASI:

112408849(TCTN2)

HAMP:

307062136(TCTN2)

ECB:	100630826(TCTN2)

EPZ:	103549890(TCTN2)

EAI:	106842342(TCTN2)

MYB:	102247644(TCTN2)

MYD:	102762275(TCTN2)

MMYO:

118655517(TCTN2)

MLF:	102436026(TCTN2)

MDT:	132221882(TCTN2)

MYUM:

138997784(TCTN2)

PKL:	118710435(TCTN2)

EFUS:

103300386(TCTN2)

MNA:	107529652(TCTN2)

DRO:	112310804(TCTN2)

SHON:

118991019(TCTN2)

AJM:	119060811(TCTN2)

PDIC:

114509644(TCTN2)

PHAS:

123822717(TCTN2)

MMF:	118639953(TCTN2)

PPAM:

129087394(TCTN2)

HAI:	109386113(TCTN2)

RFQ:	117017187(TCTN2)

RHII:

308492438(TCTN2)

PALE:

102896004(TCTN2)

PGIG:

120616013(TCTN2)

PVP:	105289363(TCTN2)

RAY:	107515199(TCTN2)

MJV:	108409907(TCTN2)

TOD:	119245060(TCTN2)

SARA:

101539344(TCTN2)

SFUM:

130039524(TCTN2)

SETR:

126002052(TCTN2)

LAV:	100662238(TCTN2)

TMU:

101353772

ETF:	101642580(TCTN2)

DNM:	101440566(TCTN2)

MDO:	103106109(TCTN2)

GAS:	123256847(TCTN2)

SHR:	100934845(TCTN2)

AFZ:

127545394

PCW:	110196838(TCTN2)

TVP:	118834331(TCTN2)

PBRV:

138156202(TCTN2)

OAA:	114809074(TCTN2)

TACU:

119942754(TCTN2)

GGA:	100857705(TCTN2)

PCOC:

116228642(TCTN2)

MGP:	104913534(TCTN2)

CJO:	107321172(TCTN2)

TPAI:

128084616(TCTN2)

LMUT:

125701839(TCTN2)

NMEL:

110406286(TCTN2)

APLA:

110352116(TCTN2)

AACU:

137841432(TCTN2)

OJA:	118174769(TCTN2)

BCLA:

308450400(TCTN2)

ACYG:

106031421(TCTN2)

ABRC:

308179648(TCTN2)

CATA:

118257237(TCTN2)

AFUL:

116496319(TCTN2)

TGU:	101233444(TCTN2)

LSR:	110471804(TCTN2)

VMC:	128816250(TCTN2)

VCHA:

128797369(TCTN2)

AIB:	137484501(TCTN2)

SCAN:

103818191(TCTN2)

PMOA:

120509630(TCTN2)

OTC:	121338888(TCTN2)

PRUF:

121364919(TCTN2)

ATRC:

139598509(TCTN2)

MATE:

118692952(TCTN2)

MAEN:

136564291(TCTN2)

GFR:	102037325(TCTN2)

FAB:	101806313(TCTN2)

OMA:	130259672(TCTN2)

PHI:	102107544(TCTN2)

PMAJ:

107211428(TCTN2)

CCAE:

111936359(TCTN2)

CCW:	104688728(TCTN2)

CBRC:

103616012(TCTN2)

ACOE:

138119066(TCTN2)

ETL:	114054948(TCTN2)

ZAB:	102075474(TCTN2)

ZLE:	135454514(TCTN2)

ACHL:

103811346(TCTN2)

SVG:	106852476(TCTN2)

MMEA:

130580997(TCTN2)

LCAI:

146430111(TCTN2)

HRT:	120760740(TCTN2)

SATI:

136369093(TCTN2)

CFAI:

136298832(TCTN2)

CCIC:

134050970(TCTN2)

NNT:

104399419

SHAB:

115614950(TCTN2)

POCC:

134166462(TCTN2)

PECH:

308226512(TCTN2)

FPG:	101914041(TCTN2)

FCH:	102052637(TCTN2)

FRS:	119142431(TCTN2)

CCRI:

104154850(TCTN2)

ACUN:

113486154(TCTN2)

ANOC:

141967238(TCTN2)

SURA:

141951093(TCTN2)

TALA:

104355604(TCTN2)

ACHC:

115345788(TCTN2)

HALD:

104310759(TCTN2)

HLE:	104840928(TCTN2)

AGEN:

126040318

HHAR:

128146410(TCTN2)

BBUT:

142037237(TCTN2)

GCL:

127022853

CSTI:

104549723(TCTN2)

LDI:	104340166(TCTN2)

MNB:	103772789(TCTN2)

DPUB:

104308464(TCTN2)

PPUS:

135188993(TCTN2)

IIN:	128975765(TCTN2)

AVIT:

104267371(TCTN2)

BRHI:

104497226(TCTN2)

EGZ:	104130154(TCTN2)

NNI:	104020941(TCTN2)

PLEC:

309596694(TCTN2)

PCRI:

104030322(TCTN2)

PCAO:

104047876(TCTN2)

PADL:

103914545(TCTN2)

AFOR:

103902874(TCTN2)

FGA:	104069484(TCTN2)

CBOR:

142090239(TCTN2)

GSTE:

104250661(TCTN2)

CBOY:

140660074(TCTN2)

MAME:

142416664(TCTN2)

CLV:	102090515(TCTN2)

CNIC:

135995260(TCTN2)

NMAY:

308047258(TCTN2)

MUI:	104545736(TCTN2)

PGUU:

104457811(TCTN2)

PLET:

104613980(TCTN2)

EHS:	104503525(TCTN2)

CMAC:

104473810(TCTN2)

CUCA:

104068457(TCTN2)

PCUR:

138728131(TCTN2)

TEO:	104370181(TCTN2)

BREG:

104629438(TCTN2)

GAME:

129213679(TCTN2)

OHA:	104327603(TCTN2)

ACAR:

104518387(TCTN2)

CEUR:

306726883(TCTN2)

CPEA:

104388758(TCTN2)

HEK:	139805069(TCTN2)

CVF:	104282251(TCTN2)

RTD:	128917057(TCTN2)

CRID:

134522749(TCTN2)

LMIC:

141750938(TCTN2)

NARQ:

141472614(TCTN2)

AAM:	106497680(TCTN2)

AROW:

112962525(TCTN2)

NPD:	112945869(TCTN2)

TGT:	104574848(TCTN2)

DNE:	112991866(TCTN2)

SCAM:

104138823(TCTN2)

ASN:	102380461(TCTN2)

AMJ:	102570862(TCTN2)

CPOO:

109312715(TCTN2)

GGN:	109290509(TCTN2)

PSS:	102449285(TCTN2)

CMY:	102947079(TCTN2)

CCAY:

125622801(TCTN2)

DCC:	119843937(TCTN2)

TST:	117887882(TCTN2)

ACS:	103279290(tctn2)

ASAO:

132781359(TCTN2)

PVT:	110083825(TCTN2)

SUND:

121916493(TCTN2)

PBI:	103055282(TCTN2)

PMUR:

107285457(TCTN2)

CTIG:

120316676(TCTN2)

TSR:	106552087(TCTN2)

PGUT:

117672145(TCTN2)

PCAE:

139321980(TCTN2)

APRI:

131185678(TCTN2)

PTEX:

113448605(TCTN2)

NSS:	113425029(TCTN2)

VKO:	123028563(TCTN2)

PMUA:

114586287 114586288

PRAF:

128403670(TCTN2)

ZVI:	118075717(TCTN2)

HCG:	128337998(TCTN2)

GJA:	107117228(TCTN2)

STOW:

125443154(TCTN2)

EMC:	129341318(TCTN2)

XLA:	108695669(tctn2.L)

XTR:	733954(tctn2)

NPR:	108787377(TCTN2)

RTEM:

120934689(TCTN2)

ACAT:

141140437(TCTN2)

PADS:

140332734(TCTN2)

BBUF:

120991406(TCTN2)

BGAR:

122924510(TCTN2)

DTC:	141098366(TCTN2)

PWL:	138266331(TCTN2)

MUO:	115479623(TCTN2)

GSH:	117365191(TCTN2)

DRE:	563835(tctn2)

DAES:

130228427(tctn2)

SRX:

107741513

SANH:

107704714

SGH:

107599155

CCAR:

109090427(tctn2)

CAUA:

113068078(tctn2)

CGIB:

127958567

PTET:

122345962(tctn2)

LROH:

127164736(tctn2)

GRF:	141335743(tctn2)

OMC:	131540071(tctn2)

PPRM:

120470448(tctn2)

RKG:	130088105(tctn2)

SCEP:

307159354(tctn2)

PPHX:

306995689(tctn2)

MAMB:

125267345(tctn2)

CIDE:

127512187

CERY:

137034360(tctn2)

MASI:

127418231

TROS:

130568639(tctn2)

TDW:	130419510(tctn2)

MANU:

129439726(tctn2)

PDAB:

135732654(tctn2)

IPU:

108255514

IFU:	128598998(tctn2)

PHYP:

113536938(tctn2)

SMEO:

124380438(tctn2)

TFD:	113653316(tctn2)

TVC:	132855175(tctn2)

CGAR:

128509450(tctn2)

NGRA:

132872518(tctn2)

TRN:	134335701(tctn2)

AMEX:

103022260(tctn2)

CMAO:

118827720(tctn2)

EEE:	113585584(tctn2)

CHAR:

105896798(tctn2)

SPIL:

134089678(tctn2)

ASAD:

121715870(tctn2)

TRU:	105418033(tctn2)

TFS:	130525592(tctn2)

NCC:	104950173(tctn2)

TBEN:

117496848(tctn2)

CGOB:

115013695(tctn2)

PGEO:

117452696(tctn2)

GACU:

117561117(tctn2)

EMAC:

134873429(tctn2)

ELY:	117252325(tctn2)

EFO:	125890057(tctn2)

PLEP:

121944853(tctn2)

ECRA:

117945011(tctn2)

PFLV:

114555531(tctn2)

GAT:	120830252(tctn2)

PPUG:

119225359(tctn2)

AFB:	129101586(tctn2)

CLUM:

117736287(tctn2)

PSWI:

130197416(tctn2)

CANA:

137805244(tctn2)

CVE:	137866892(tctn2)

MSAM:

119892299(tctn2)

SCHU:

122876255(tctn2)

EARM:

139283709(tctn2)

CUD:	121509954(tctn2)

SPUL:

138610968(tctn2)

LMIX:

132974914

HTC:	141791001(tctn2)

ALAT:

119019494(tctn2)

ASTR:

137592362(tctn2)

PKLU:

139204085(tctn2)

LCO:	104920369(tctn2)

MZE:	101468351(tctn2)

ONL:	102079034(tctn2)

OAU:	116332358(tctn2)

OLA:	101155357(tctn2)

OML:	112147884(tctn2)

CSAI:

133451260(tctn2)

XMA:	102223260(tctn2)

XCO:	114155275(tctn2)

XHE:	116730484(tctn2)

PRET:

103470301(tctn2)

PFOR:

103142851(tctn2)

PLAI:

106937145(tctn2)

PMEI:

106918065(tctn2)

GAF:	122827929(tctn2)

PPRL:

129371951(tctn2)

CVG:	107091234 107091235

CTUL:

119790099(tctn2)

GMU:	124878016(tctn2)

NFU:	107394197(tctn2)

KMR:	108234483(tctn2)

ALIM:

106521673(tctn2)

NWH:	119413364(tctn2)

LTU:	140309884(tctn2)

MCEP:

125012140(tctn2)

AOCE:

111575839(tctn2)

EJA:	138215747(tctn2)

BFRE:

138627326(tctn2)

LCF:

108878007

CSEM:

103398614(tctn2)

POV:	109638114(tctn2)

SSEN:

122769923(tctn2)

SSOE:

131463562(tctn2)

HHIP:

117768244(tctn2)

HSP:	118114463(tctn2)

PPLT:

128438293(tctn2)

SMAU:

118314502(tctn2)

SDU:	111230213(tctn2)

SLAL:

111660295(tctn2)

XGL:	120804764(tctn2)

HCQ:	109511652(tctn2)

SSCV:

125994491(tctn2)

SBIA:

133499218(tctn2)

PEE:	133400520(tctn2)

PTAO:

133475487(tctn2)

BPEC:

110169781(tctn2)

ENY:	140347200(tctn2)

MALB:

109961571(tctn2)

BSPL:

114862178(tctn2)

SJO:	128365034(tctn2)

SSCO:

133979205(tctn2)

TTY:	137196983(tctn2)

GMH:	115545248(tctn2)

SASA:

106580323(tctn2)

STRU:

115200201(tctn2)

OTW:	112248519(tctn2)

OMY:	110536100(tctn2)

OGO:	124035223(tctn2)

ONE:	115140110(tctn2)

OKI:	109895955(tctn2)

OKE:	118358398(tctn2)

OMM:	135514032(tctn2)

OCLA:

139390173

SALP:

111958227(tctn2)

SNH:	120062659(tctn2)

SFON:

129826392(tctn2)

CCLU:

121587355(tctn2)

ELS:	105025612(tctn2)

OEP:	134012136(tctn2)

SFM:	108932531(tctn2)

PKI:	111839977(tctn2)

AANG:

118206429(tctn2)

AROT:

135264713(tctn2)

CCOG:

133140736(tctn2)

LOC:	102687252(tctn2)

PSPA:

121299892(tctn2)

ARUT:

117427098 117963183

PSEX:

120540881(tctn2)

LCM:	102351376(TCTN2)

CMK:	103188003(tctn2)

RTP:

109936925

CPLA:

122551018(tctn2)

CPUN:

140488025(tctn2)

HOC:	132826995(tctn2)

SCAU:

119966498(tctn2)

LERI:

129709240(tctn2)

HAKA:

140730937(tctn2)

PMRN:

116939203

LRJ:	133348340(TCTN2)

BFO:

BBEL:

CIN:

SCLV:

CLEP:

SPU:

APLC:

SKO:

ZNE:

CSEC:

EAF:

LSM:

TCF:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

PTRU:

SPRM:

ESN:

MNZ:

MRJ:

PORN:

OOT:

CSCU:

CVS:

LGI:	LOTGIDRAFT_228304

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

OED:

MYI:

PMAX:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LAK:	106153254(LOC106153254)

NVE:

116612443

EPA:

110232745

ATEN:

116296119

ADF:	107332547 107332821

AMIL:

PDAM:

SPIS:

DGT:

XEN:

Reference

PMID:16357211

Authors

Reiter JF, Skarnes WC

Title

Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition.

Journal

Genes Dev 20:22-7 (2006)
DOI:10.1101/gad.1363606

Sequence

[hsa:79867]

LinkDB

DBGET integrated database retrieval system