KEGG ORTHOLOGY: K19363

ORTHOLOGY: K19363

Entry

K19363                      KO

Symbol

LITAF

Name

lipopolysaccharide-induced tumor necrosis factor-alpha factor

Pathway

map04142

Lysosome biogenesis

Disease

H00264

Charcot-Marie-Tooth disease

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome biogenesis
    K19363  LITAF; lipopolysaccharide-induced tumor necrosis factor-alpha factor

Other DBs

GO:

0050699

Genes

HSA:	9516(LITAF)

PTR:	453923(LITAF)

PPS:	100968533(LITAF)

GGO:	101134322(LITAF)

PON:	100447960 112131632 129050922(LITAF)

PPYG:

129015428(LITAF) 129015901

NLE:	100590089(LITAF)

HMH:	116462782(LITAF)

SSYN:

129462626(LITAF)

MCC:	711743(LITAF)

MCF:	102137349(LITAF)

MTHB:

126944764

MNI:	105467758(LITAF)

CSAB:

103228362(LITAF)

CATY:

105572182(LITAF)

PANU:

101012122(LITAF)

TGE:	112614836(LITAF)

MLEU:

105545255(LITAF)

RRO:	104667701(LITAF)

RBB:	108541225(LITAF)

PTEH:

111555230(LITAF)

CANG:

105525682(LITAF)

CJC:	100401290(LITAF)

SBQ:	101051813(LITAF)

CIMI:

108312184(LITAF)

ANAN:

105713757 105717822(LITAF)

CSYR:

103251809(LITAF)

MMUR:

105882339(LITAF)

LCAT:

123632388(LITAF)

ERUF:

138394682(LITAF)

PCOQ:

105813098(LITAF)

OGA:	100946792(LITAF)

MMU:	56722(Litaf)

MCAL:

110311449(Litaf)

MPAH:

110329675(Litaf)

RNO:	65161(Litaf)

MCOC:

116085237(Litaf)

ANU:	117711900(Litaf)

ASYL:

127694595(Litaf)

MUN:	110559017(Litaf)

CGE:	100769636(Litaf)

MAUA:

101829118(Litaf)

PROB:

127219670(Litaf)

PLEU:

114695544(Litaf)

PMAV:

102925395(Litaf)

MORG:

121463957(Litaf)

MFOT:

126491597

AAMP:

119813286(Litaf)

CNL:	130877539(Litaf)

NGI:	103731574(Litaf)

HGL:	101725320(Litaf)

CPOC:

100729493(Litaf)

CCAN:

109688734(Litaf)

DORD:

105982200(Litaf)

DSP:

122123820

DMER:

138814531(Litaf)

PLOP:

125340620(Litaf)

NCAR:

124970439

SVUL:

306649927(LITAF)

MMMA:

107146479(Litaf)

ITI:	101977836(Litaf)

SCIL:

308651667(LITAF)

MAVE:

308269310(LITAF)

OCU:

100348894

OPI:	101529864(LITAF)

OCZ:	121151668(LITAF)

TUP:	102499986(LITAF)

GVR:	103609372(LITAF)

CFA:	119871594 490004(LITAF)

CLUD:

112640367(LITAF)

VVP:	112923324(LITAF)

VLG:	121487655(LITAF)

NPO:	129501677 129520061(LITAF)

AML:	100481432(LITAF)

UMR:	103668603(LITAF)

UAH:	113270792(LITAF)

UAR:	123783554(LITAF)

ELK:

111156021

LLV:

125090592

MPUF:

101689293(LITAF)

MNP:	132026899(LITAF)

MLK:	131819390(LITAF)

NVS:	122895937(LITAF)

MMAQ:

308359347(LITAF)

ORO:	101375855(LITAF)

EJU:	114219830(LITAF)

ZCA:	113932423(LITAF)

MLX:	118021833(LITAF)

MANO:

123844461(LITAF)

NSU:	110587868(LITAF)

LWW:	102734039(LITAF)

FCA:	101083562(LITAF)

PYU:	121019512(LITAF)

PCOO:

112853312(LITAF)

PBG:	122471664(LITAF)

PVIV:

125154183(LITAF)

LRUF:

124517859

LGF:	123589800(LITAF)

AJU:

106989158

PTG:	102961915(LITAF)

PPAD:

109278331(LITAF)

PUC:

125927891

PLEZ:

122209381(LITAF)

HHV:	120232717(LITAF)

CCRU:

144239240(LITAF)

BTA:	520564(LITAF)

BOM:	102283734(LITAF)

BIU:	109578593(LITAF)

BJV:	133238249(LITAF)

BBUB:

102413690(LITAF)

BKE:	129637518(LITAF)

BBIS:

104996419(LITAF)

CHX:	102191665(LITAF)

OAS:	101109408(LITAF)

OCAN:

138428968(LITAF)

BTAX:

128043766(LITAF)

CSUM:

138075653(LITAF)

ODA:	120855788(LITAF)

CCAD:

122433087(LITAF)

MREE:

136160534(LITAF)

OVR:	110129293(LITAF)

MBEZ:

129545378(LITAF)

SSC:	100518302(LITAF)

CFR:	102512479(LITAF)

CBAI:

105074247(LITAF)

CDK:	105089040(LITAF)

VPC:	102525623(LITAF)

BACU:

103000215(LITAF)

BMUS:

118881203(LITAF) 118897273

LVE:	103088398(LITAF)

OOR:	101288730(LITAF) 117201933

LALB:

132505219(LITAF)

GMF:	115867647(LITAF)

DDP:	132438006(LITAF)

SCOO:

307198796(LITAF)

PCRS:

137207146(LITAF)

DLE:	111163543(LITAF)

PCAD:

102991374(LITAF)

PSIU:

116739491(LITAF) 116755766

PPHC:

136135208(LITAF)

NASI:

112399176(LITAF)

HAMP:

307054650(LOC307054650) 307063663(LITAF)

ECB:	100033923(LITAF)

EPZ:	103557145(LITAF)

EAI:	106836749(LITAF)

MYB:	102240148(LITAF)

MYD:	102766492(LITAF)

MMYO:

118655814(LITAF)

MLF:	102441958(LITAF)

MDT:	132233089(LITAF)

MYUM:

138994160

PKL:	118703839(LITAF)

EFUS:

103286111(LITAF)

POTS:

308253580(LITAF)

MNA:	107525441(LITAF)

DRO:	112314935(LITAF)

SHON:

119002903(LITAF)

AJM:	119053567(LITAF)

PDIC:

114509785(LITAF)

PHAS:

123806476(LITAF)

MMF:	118641585(LITAF)

PPAM:

129083681(LITAF)

HAI:	109387179(LITAF)

RFQ:	117019381(LITAF)

PALE:

102878983(LITAF)

PGIG:

120620393(LITAF)

PVP:	105290929(LITAF)

RAY:	107518197(LITAF)

MJV:	108393821(LITAF)

TOD:	119241929(LITAF)

SARA:

101551729(LITAF)

SFUM:

130016673(LITAF)

SETR:

126001324(LITAF)

LAV:	100657280(LITAF)

TMU:

101356368

ETF:

101656517

DNM:	101419932(LITAF)

MDO:	100017771(LITAF)

GAS:	123232939(LITAF)

SHR:	100914625(LITAF)

AFZ:

127539201

PCW:	110198332(LITAF)

TVP:	118831330(LITAF)

PBRV:

138159596(LITAF)

MLAO:

141495265(LITAF)

OAA:	100078855(LITAF)

TACU:

119942724(LITAF)

GGA:	374125(LITAF)

PCOC:

116237406(LITAF)

MGP:	100545032(LITAF)

CJO:	107320782(LITAF)

TPAI:

128078856(LITAF)

LMUT:

125700857(LITAF)

NMEL:

110405851(LITAF)

APLA:

101800838(LITAF)

AACU:

137865139(LITAF)

OJA:	118174349(LITAF)

BCLA:

308449685(LITAF)

ACYG:

106041216(LITAF)

CATA:

118249290(LITAF)

AFUL:

116495424(LITAF)

TGU:	100225426(LITAF)

LSR:	110474522(LITAF)

VMC:	128815606(LITAF)

VCHA:

128796400(LITAF)

AIB:	137483572(LITAF)

SCAN:

103817725(LITAF)

PMOA:

120513077(LITAF)

OTC:	121334578(LITAF)

PRUF:

121350886(LITAF)

ATRC:

139598193(LITAF)

MATE:

118692807(LITAF)

MAEN:

136563482(LITAF)

GFR:	102041275(LITAF)

FAB:	101817551(LITAF)

OMA:	130259451(LITAF)

PHI:	102099508(LITAF)

PMAJ:

107211340(LITAF)

CCAE:

111935945(LITAF)

CCW:	104684711(LITAF)

CBRC:

103615353(LITAF)

ACOE:

138118673(LITAF)

ETL:	114058476(LITAF)

ZAB:	102062772(LITAF)

ZLE:	135454292(LITAF)

ACHL:

103801190(LITAF)

SVG:	106865012(LITAF)

MMEA:

130574212(LITAF)

HRT:	120759809(LITAF)

CFAI:

136297810(LITAF)

CCIC:

134050544

NNT:	104398979(LITAF)

SHAB:

115606455(LITAF)

POCC:

134160132(LITAF)

FPG:	101913058(LITAF)

FCH:	102054931(LITAF)

FRS:	119146422(LITAF)

CCRI:

104156191

ACUN:

113485591(LITAF)

ANOC:

141966709(LITAF)

SURA:

141950607(LITAF)

TALA:

104356355(LITAF)

ACHC:

115335835(LITAF)

HALD:

104312729(LITAF)

HLE:	104838616(LITAF)

AGEN:

126053366

HHAR:

128134689(LITAF)

BBUT:

142045123(LITAF)

GCL:

127022620

CSTI:

104561387(LITAF)

LDI:	104341322(LITAF)

MNB:	103772311(LITAF)

DPUB:

104298736(LITAF)

PPUS:

135180522(LITAF)

IIN:	128974378(LITAF)

AVIT:

104266995(LITAF)

BRHI:

104492301(LITAF)

EGZ:	104126968(LITAF)

NNI:	104023450(LITAF)

PCRI:

104029455(LITAF)

PCAO:

104048785(LITAF)

PARX:

142062625(LITAF)

PADL:

103917567(LITAF)

AFOR:

103900875(LITAF)

FGA:	104069086(LITAF)

CBOR:

142089056(LITAF)

GSTE:

104250209(LITAF)

CBOY:

140659031(LITAF)

MAME:

142415995(LITAF)

CLV:

102092663

CNIC:

135994293(LITAF)

NMAY:

308046054(LITAF)

MUI:	104534923(LITAF)

PGUU:

104461849(LITAF)

PLET:

104615321(LITAF)

EHS:	104504549(LITAF)

CMAC:

104474674

CUCA:

104058767(LITAF)

PCUR:

138727824(LITAF)

TEO:	104370842(LITAF)

BREG:

104628978(LITAF)

GAME:

129213277(LITAF)

OHA:	104330997(LITAF)

ACAR:

104519320

CEUR:

306725935(LITAF)

CPEA:

104393689(LITAF)

CVF:	104287856(LITAF)

RTD:	128914058(LITAF)

CRID:

134519671(LITAF)

LMIC:

141747484(LITAF)

NARQ:

141471698(LITAF)

AAM:	106482607(LITAF)

AROW:

112964133(LITAF)

NPD:

112955738

TGT:	104574216(LITAF)

DNE:	112981055(LITAF)

SCAM:

104149709(LITAF)

ASN:	102376832(LITAF)

AMJ:	102570574(LITAF)

CPOO:

109313506(LITAF)

GGN:	109290731(LITAF)

PSS:	102443753(LITAF)

CIZ:	142021620(LITAF)

CMY:	102933182(LITAF)

CCAY:

125643824(LITAF)

LKP:	140918333(LITAF)

NDS:	141994413(LITAF)

DCC:	119862938(LITAF)

CPIC:

101938673(LITAF)

TST:	117883778(LITAF)

EOB:	135884391(LITAF)

CABI:

116824395(LITAF)

MRV:	120373880(LITAF)

EMQ:	137155203(LITAF)

ASAO:

132781558(LITAF)

PVT:	110087060(LITAF)

SUND:

121914220(LITAF)

PMUR:

107284006(LITAF)

CTIG:

120319253(LITAF)

TSR:	106551887(LITAF)

PGUT:

117679485(LITAF)

PCAE:

139325315(LITAF)

APRI:

131185057(LITAF)

PTEX:

113438875

NSS:	113422415(LITAF)

VKO:	123024936(LITAF)

PMUA:

114584547(LITAF)

PRAF:

128408689

ZVI:	118093046(LITAF)

HCG:

128336823

GJA:	107109284(LITAF)

EMC:	129340180(LITAF)

XLA:	108701526(litaf.L) 734870(litaf.S)

XTR:	394567(litaf)

BBUF:

121007424(LITAF)

BGAR:

122945130(LITAF)

DTC:	141047665(LITAF)

HSQ:	130284205(LITAF)

PCOB:

134945176(LITAF)

PWL:	138261404(LITAF)

MUO:

115476446

GSH:	117368903(LITAF)

DRE:	431731(litaf) 796031(si:dkeyp-75b4.8)

DAES:

130219351(si:dkeyp-75b4.8) 130221678(litaf)

SRX:	107745584(litaf)

SANH:

107674718 107692693 107703380

SGH:	107565146 107568939(litaf)

CCAR:

109054695 122138844

CAUA:

113044801 113071528

CGIB:

127949734(si:dkeyp-75b4.8) 127953842

PTET:

122335928(si:dkeyp-75b4.8) 122341679(litaf)

LROH:

127163112(litaf) 127167693(si:dkeyp-75b4.8)

OMC:	131537829(litaf) 131546263(si:dkeyp-75b4.8)

PPRM:

120489598(litaf)

RKG:	130071030(litaf)

SCEP:

307159956(litaf)

MAMB:

125270016(litaf) 125272749

CIDE:

127509194 127522224(si:dkeyp-75b4.8)

CERY:

137017805(litaf)

MASI:

127444460(si:dkeyp-75b4.8) 127450083

TROS:

130552596(si:dkeyp-75b4.8) 130561564(litaf)

TDW:	130412185(si:dkeyp-75b4.8) 130426323(litaf)

MANU:

129432035(litaf) 129445505

PDAB:

135735481 135740063 135740127(litaf)

IPU:	100528736(litaf) 108258686(si:dkeyp-75b4.8)

IFU:	128600289(litaf) 128602266(si:dkeyp-75b4.8)

PHYP:

113536264(litaf)

SMEO:

124375801(litaf) 124377840(si:dkeyp-75b4.8)

TFD:	113660401(litaf) 125139348(si:dkeyp-75b4.8)

TVC:	132837609(litaf) 132839602(si:dkeyp-75b4.8)

CGAR:

128506306(si:dkeyp-75b4.8) 128518791(litaf)

NGRA:

132866662(si:dkeyp-75b4.8) 132900803(litaf)

TRN:	134331173(litaf)

AMEX:

103041887(litaf) 103047052(si:dkeyp-75b4.8)

CMAO:

118798100(si:dkeyp-75b4.8) 118805749(litaf)

EEE:	113574926 113588344

CHAR:

122131962(litaf)

SPIL:

134077401(litaf) 134099821

ASAD:

121684667 121705399(litaf)

TRU:

105417687

TFS:

130527012

NCC:

104951075

TBEN:

117482166(si:dkeyp-75b4.8)

CGOB:

115015335

PGEO:

117448144

GACU:

117556086(si:dkeyp-75b4.8)

EMAC:

134864017(si:dkeyp-75b4.8)

ELY:

117254731

EFO:	125885739(si:dkeyp-75b4.8)

PLEP:

121941494(si:dkeyp-75b4.8)

SLUC:

116051755(si:dkeyp-75b4.8)

SVIT:

144526356

ECRA:

117954262(si:dkeyp-75b4.8)

ESP:

116704882

PFLT:

120565130(si:dkeyp-75b4.8)

GAT:	120824922(si:dkeyp-75b4.8)

PPUG:

119218334(si:dkeyp-75b4.8)

AFB:	129095219(si:dkeyp-75b4.8)

CLUM:

117734154(si:dkeyp-75b4.8)

CANA:

137793272(si:dkeyp-75b4.8)

CVE:

137885212

AMIR:

142950026

MSAM:

119919308

SCHU:

122874074(si:dkeyp-75b4.8)

EARM:

139298960

CUD:	121509157(si:dkeyp-75b4.8)

SPUL:

138594246

LMIX:

132988494(si:dkeyp-75b4.8)

HTC:

141800914

ALAT:

119020852(si:dkeyp-75b4.8)

PKLU:

LCO:

MZE:

ONL:

OLA:

OML:

CSAI:

133451836(si:dkeyp-75b4.8)

XMA:

XCO:

XHE:

PRET:

PPRL:

CVG:

CTUL:

119797167(si:dkeyp-75b4.8)

GMU:	124868716(si:dkeyp-75b4.8)

NFU:

107388567

KMR:	108234787(si:dkeyp-75b4.8)

ALIM:

106519673

NWH:

119422914

LTU:

140305029

MCEP:

125001112(si:dkeyp-75b4.8)

AOCE:

111584393(si:dkeyp-75b4.8)

EJA:

138209106

LCF:	108901649(si:dkeyp-75b4.8)

CSEM:

103383596

POV:

109638287

SSEN:

122771377(si:dkeyp-75b4.8)

SSOE:

131466987(si:dkeyp-75b4.8)

HHIP:

117770104(si:dkeyp-75b4.8)

HSP:

118122463

PPLT:

128432672(si:dkeyp-75b4.8)

SMAU:

118313029(si:dkeyp-75b4.8)

SDU:

111216627

SLAL:

111663269

XGL:	120800894(si:dkeyp-75b4.8)

BPEC:

110167624

ENY:

140378310

MALB:

109968234

BSPL:

114852867(si:dkeyp-75b4.8)

SJO:	128380119(si:dkeyp-75b4.8)

TTY:	137179982(si:dkeyp-75b4.8)

GMH:

115539833

SASA:

106600771 106607342(LITAF)

STRU:

115189869 115198644(litaf)

OTW:	112245987(litaf) 121844170(si:dkeyp-75b4.8)

OMY:	100305217(litaf) 110516674

OGO:	124015082(litaf) 124024241

ONE:

115104181

OKI:	109898456 116370999

OKE:	118365329(litaf) 127924842(si:dkeyp-75b4.8)

OMM:	135535922 135554093(litaf)

OCLA:

139364725 139398788

SALP:

111980512

SNH:	120034063(litaf)

SFON:

129833067(litaf)

CCLU:

121537568(si:dkeyp-75b4.8) 121550733

ELS:

105013231

OEP:	134007945(litaf)

SFM:

114910585

PKI:

111836923

AANG:

118216571(litaf)

AROT:

135244256(litaf)

CCOG:

133115103(litaf)

LOC:	102683058 107078993

PSPA:

121300955

ARUT:

117418330 117973690(litaf)

PSEX:

120542040(litaf)

LCM:	102351910(LITAF)

RTP:	109921390(litaf)

CPLA:

CPUN:

HOC:

SCAU:

STOZ:

140394024(litaf)

LERI:

HAKA:

BBIF:

BHUN:

SDM:

HRF:

HASI:

HCRA:

MYI:

AIRR:

MMER:

LJP:

SMM:	Smp_060220

NVE:

EPA:

ATEN:

ADF:

AMIL:

AMUA:

MCAZ:

MFOO:

PDAM:

SPIS:

Reference

PMID:21326863

Authors

Eaton HE, Desrochers G, Drory SB, Metcalf J, Angers A, Brunetti CR

Title

SIMPLE/LITAF expression induces the translocation of the ubiquitin ligase itch towards the lysosomal compartments.

Journal

PLoS One 6:e16873 (2011)
DOI:10.1371/journal.pone.0016873

Sequence

[hsa:9516]

Reference

PMID:23166352

Authors

Lee SM, Chin LS, Li L

Title

Charcot-Marie-Tooth disease-linked protein SIMPLE functions with the ESCRT machinery in endosomal trafficking.

Journal

J Cell Biol 199:799-816 (2012)
DOI:10.1083/jcb.201204137

Sequence

[hsa:9516]

LinkDB

DBGET integrated database retrieval system