KEGG   ORTHOLOGY: K19379
Entry
K19379                      KO                                     
Symbol
F
Name
Morbillivirus fusion glycoprotein F0
Pathway
map03230  Viral genome structure
map03265  Virion - Ebolavirus, Lyssavirus and Morbillivirus
map05162  Measles
Network
nt06169  Measles virus (MV)
nt06537  TCR/BCR signaling
  Element
N00684  MV F/H to CD28-PI3K signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03230 Viral genome structure
    K19379  F; Morbillivirus fusion glycoprotein F0
   03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
    K19379  F; Morbillivirus fusion glycoprotein F0
 09160 Human Diseases
  09172 Infectious disease: viral
   05162 Measles
    K19379  F; Morbillivirus fusion glycoprotein F0
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K19379  F; Morbillivirus fusion glycoprotein F0
   03210 Viral fusion proteins
    K19379  F; Morbillivirus fusion glycoprotein F0
Viral proteins [BR:ko03200]
 -ssRNA viruses
  Measles virus
   K19379  F; Morbillivirus fusion glycoprotein F0
Viral fusion proteins [BR:ko03210]
 Class I fusion proteins
  Paramyxoviridae
   K19379  F; Morbillivirus fusion glycoprotein F0
Virus entry [br03220.html]
 Viral entry protein - human receptor protein interactions
  K19379
Genes
VG: 1489793(CDVgp5) 1489800(F) 26123434(F) 2658692(F) 3021776(RPVgp5) 3119771(F)
Reference
PMID:25520515
  Authors
Watanabe S, Ohno S, Shirogane Y, Suzuki SO, Koga R, Yanagi Y
  Title
Measles virus mutants possessing the fusion protein with enhanced fusion activity spread effectively in neuronal cells, but not in other cells, without causing strong cytopathology.
  Journal
J Virol 89:2710-7 (2015)
DOI:10.1128/JVI.03346-14
  Sequence
[vg:1489800]
Reference
PMID:25670774
  Authors
Jurgens EM, Mathieu C, Palermo LM, Hardie D, Horvat B, Moscona A, Porotto M
  Title
Measles fusion machinery is dysregulated in neuropathogenic variants.
  Journal
MBio 6:e02528-14 (2015)
DOI:10.1128/mBio.02528-14
  Sequence
[vg:1489800]
LinkDB

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