KEGG   ORTHOLOGY: K19379
Entry
K19379                      KO                                     
Symbol
F
Name
Morbillivirus fusion glycoprotein F0
Pathway
map03230  Viral genome structure
map05162  Measles
Network
nt06114  PI3K signaling (viruses)
nt06169  Measles virus (MV)
  Element
N00684  MV F/H to CD28-PI3K signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03230 Viral genome structure
    K19379  F; Morbillivirus fusion glycoprotein F0
 09160 Human Diseases
  09172 Infectious disease: viral
   05162 Measles
    K19379  F; Morbillivirus fusion glycoprotein F0
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K19379  F; Morbillivirus fusion glycoprotein F0
   03210 Viral fusion proteins
    K19379  F; Morbillivirus fusion glycoprotein F0
Viral proteins [BR:ko03200]
 -ssRNA viruses
  Measles virus
   K19379  F; Morbillivirus fusion glycoprotein F0
Viral fusion proteins [BR:ko03210]
 Class I fusion proteins
  Paramyxoviridae
   K19379  F; Morbillivirus fusion glycoprotein F0
Genes
VG: 1489793(CDVgp5) 1489800(F) 26123434(F) 2658692(F) 3021776(RPVgp5) 3119771(F)
Reference
  Authors
Watanabe S, Ohno S, Shirogane Y, Suzuki SO, Koga R, Yanagi Y
  Title
Measles virus mutants possessing the fusion protein with enhanced fusion activity spread effectively in neuronal cells, but not in other cells, without causing strong cytopathology.
  Journal
J Virol 89:2710-7 (2015)
DOI:10.1128/JVI.03346-14
  Sequence
[vg:1489800]
Reference
  Authors
Jurgens EM, Mathieu C, Palermo LM, Hardie D, Horvat B, Moscona A, Porotto M
  Title
Measles fusion machinery is dysregulated in neuropathogenic variants.
  Journal
MBio 6:e02528-14 (2015)
DOI:10.1128/mBio.02528-14
  Sequence
[vg:1489800]
LinkDB

KEGG   ORTHOLOGY: K19378
Entry
K19378                      KO                                     
Symbol
H
Name
Morbillivirus hemagglutinin glycoprotein
Pathway
map03230  Viral genome structure
map05162  Measles
Network
nt06114  PI3K signaling (viruses)
nt06169  Measles virus (MV)
  Element
N00684  MV F/H to CD28-PI3K signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03230 Viral genome structure
    K19378  H; Morbillivirus hemagglutinin glycoprotein
 09160 Human Diseases
  09172 Infectious disease: viral
   05162 Measles
    K19378  H; Morbillivirus hemagglutinin glycoprotein
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K19378  H; Morbillivirus hemagglutinin glycoprotein
Viral proteins [BR:ko03200]
 -ssRNA viruses
  Measles virus
   K19378  H; Morbillivirus hemagglutinin glycoprotein
Genes
VG: 1489792(CDVgp6) 1489801(H) 26123435(H) 2658693(H) 3021774(RPVgp6) 3119776(H)
Reference
  Authors
Tahara M, Ito Y, Brindley MA, Ma X, He J, Xu S, Fukuhara H, Sakai K, Komase K, Rota PA, Plemper RK, Maenaka K, Takeda M
  Title
Functional and structural characterization of neutralizing epitopes of measles virus hemagglutinin protein.
  Journal
J Virol 87:666-75 (2013)
DOI:10.1128/JVI.02033-12
  Sequence
[vg:1489801]
Reference
  Authors
Zhang X, Lu G, Qi J, Li Y, He Y, Xu X, Shi J, Zhang CW, Yan J, Gao GF
  Title
Structure of measles virus hemagglutinin bound to its epithelial receptor nectin-4.
  Journal
Nat Struct Mol Biol 20:67-72 (2013)
DOI:10.1038/nsmb.2432
  Sequence
[vg:1489801]
LinkDB

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