KEGG ORTHOLOGY: K19563

ORTHOLOGY: K19563

Entry

K19563                      KO

Symbol

bioA, bioK

Name

lysine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.105]

Pathway

map00780

Biotin metabolism

map01100

Metabolic pathways

map01240

Biosynthesis of cofactors

Module

M00123

Biotin biosynthesis, pimeloyl-ACP/CoA => biotin

M00573

Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin

M00577

Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin

Reaction

R10699

L-lysine:8-amino-7-oxononanoate aminotransferase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00780 Biotin metabolism
    K19563  bioA, bioK; lysine---8-amino-7-oxononanoate aminotransferase
Enzymes [BR:ko01000]
2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.105  lysine---8-amino-7-oxononanoate transaminase
     K19563  bioA, bioK; lysine---8-amino-7-oxononanoate aminotransferase

Other DBs

COG:

COG0161

Genes

BSU:	BSU30230(bioA)

BSR:	I33_3077(bioA)

BSL:

A7A1_1653

BSH:	BSU6051_30230(bioK)

BSY:	I653_14470

BSUT:

BSUB_03212(bioK)

BSUL:

BSUA_03212(bioK)

BSUS:

Q433_16395

BSO:	BSNT_09443(bioA)

BSN:	BSn5_05955

BSQ:	B657_30230(bioK)

BSX:	C663_2868(bioK)

BSP:	U712_15005

BSS:	BSUW23_14645(bioK)

BST:	GYO_3271(bioA)

BIT:	BIS30_04485

BLI:	BL00953(bioA)

BLD:	BLi00767(bioA)

BLH:	BaLi_c08650(bioA)

BAY:	RBAM_018280(bioA)

BAQ:	BACAU_1786(bioA)

BYA:	BANAU_1953(bioA)

BAMP:

B938_09455

BQY:	MUS_2182(bioA)

BAML:

BAM5036_1765(bioK)

BAMA:

RBAU_1803(bioK)

BAMN:

BASU_1783(bioK)

BAMB:

BAPNAU_1916(bioA)

BAMT:

AJ82_10385

BAMY:

V529_17980(bioA)

BMP:	NG74_01904(bioK)

BAO:	BAMF_1923(bioK)

BAZ:	BAMTA208_07890(bioK)

BQL:	LL3_02013(bioK)

BXH:	BAXH7_01607(bioA)

BAMI:

BAMC:

BAMF:

BSIA:

BAE:	BATR1942_12905

BVM:	B9C48_09330

BSON:

S101395_00962(bioA)

BHT:	DIC78_16485

BMOJ:

HC660_28870(bioK)

BIQ:	AN935_15130

BSTR:

QI003_18315(bioA)

BGY:	BGLY_0781(bioK)

BBAD:

K7T73_02980(bioA)

BCAB:

EFK13_15360(bioA)

BRY:	M0696_15070(bioA)

BJS:

BACI:

BACP:

BACB:

BACO:

BACY:

BACL:

BS34A_32870(bioA)

BALM:

BsLM_3007

BACS:

AUL54_01445

BACQ:

DOE78_13825

BAQU:

K6959_16180(bioA)

BHAI:

KJK41_05960(bioA)

BEO:

BEH_11235

BHA:

BH0782

BKW:	BkAM31D_02745(bioK)

BGI:	BGM20_09065

BPF:	BpOF4_04195(bioA)

CFIR:

NAF01_14655(bioA)

AFL:	Aflv_1071(bioA)

AGN:	AFK25_09050

AAYD:

B379_13255

HSHI:

MUO14_17885(bioA)

VIR:	X953_06770

VIL:	CFK37_17920

VPN:	A21D_01032(bioK_1)

RUE:	DT065_18015

MSEM:

GMB29_11990(bioA)

RAZ:	U9J35_06205(bioA)

ROSS:

V2W31_06165(bioA)

CTHU:

HUR95_16680(bioA)

ALKL:

MM271_06860(bioA)

DOM:	RRU94_17190(bioA)

ACHP:

QR721_12065(bioA)

AAC:

Aaci_2857

SPOS:

DV702_05505

SPAE:

E2C16_12250(bioA)

SURL:

BI350_00125

LKI:

LKI_05230

LEC:	LGMK_07195

» show all

Reference

PMID:15880481

Authors

Van Arsdell SW, Perkins JB, Yocum RR, Luan L, Howitt CL, Chatterjee NP, Pero JG

Title

Removing a bottleneck in the Bacillus subtilis biotin pathway: bioA utilizes lysine rather than S-adenosylmethionine as the amino donor in the KAPA-to-DAPA reaction.

Journal

Biotechnol Bioeng 91:75-83 (2005)
DOI:10.1002/bit.20488

Sequence

[bsu:BSU30230]

LinkDB

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