KEGG ORTHOLOGY: K19573

ORTHOLOGY: K19573

Entry

K19573                      KO

Symbol

ATAT1, MEC17

Name

alpha-tubulin N-acetyltransferase 1 [EC:2.3.1.108]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K19573  ATAT1, MEC17; alpha-tubulin N-acetyltransferase 1
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.108  alpha-tubulin N-acetyltransferase
     K19573  ATAT1, MEC17; alpha-tubulin N-acetyltransferase 1
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Centrosome formation proteins
   Microtubules and associated factors
    Microtubule-associated proteins
     K19573  ATAT1, MEC17; alpha-tubulin N-acetyltransferase 1

Other DBs

GO:

0019799

Genes

HSA:	79969(ATAT1)

PTR:	100612548(ATAT1)

PPS:	100975033(ATAT1)

GGO:	101125931(ATAT1)

PON:	100190967(ATAT1)

NLE:	100595319(ATAT1)

HMH:	116460080(ATAT1)

SSYN:

129472973(ATAT1)

MCC:	100141388(ATAT1)

MCF:	135970664(ATAT1)

MTHB:

126953104

MNI:	105498610(ATAT1)

CSAB:

103221829(ATAT1)

CATY:

105600029(ATAT1)

PANU:

101025462(ATAT1)

TGE:	112622364 112623033

MLEU:

105553117(ATAT1)

RRO:	104666191(ATAT1)

RBB:	108522570(ATAT1)

TFN:	117088379(ATAT1)

PTEH:

111534440(ATAT1)

CANG:

105513991(ATAT1)

CJC:	100388531(ATAT1)

SBQ:	101037052(ATAT1)

CIMI:

108290611(ATAT1)

ANAN:

105704565(ATAT1)

CSYR:

103249229(ATAT1)

MMUR:

105855392(ATAT1)

LCAT:

123631692(ATAT1)

PCOQ:

105817287(ATAT1)

OGA:	100950093(ATAT1)

MMU:	73242(Atat1)

MCAL:

110284357(Atat1)

MPAH:

110335546(Atat1)

RNO:	361789(Atat1)

MCOC:

116074613(Atat1)

ANU:	117724213(Atat1)

ASYL:

127669109(Atat1)

MUN:	110557137(Atat1)

CGE:	100764669(Atat1)

MAUA:

101826157(Atat1)

PROB:

127224374(Atat1)

PLEU:

114687012(Atat1)

MORG:

121435419(Atat1)

MFOT:

126494399

AAMP:

119822967(Atat1)

NGI:	103740567(Atat1)

HGL:	101705887(Atat1)

CPOC:

100719818(Atat1)

CCAN:

109693536(Atat1)

DORD:

105996955(Atat1)

DSP:	122111311(Atat1)

PLOP:

125352768

NCAR:

124988608

MMMA:

107160426(Atat1)

ITI:	101963299(Atat1)

OCU:

100358006

OPI:	101531705(ATAT1)

TUP:	102486128(ATAT1)

GVR:	103592545(ATAT1)

CFA:	477580(ATAT1) 609464

CLUD:

112641245(ATAT1) 112656233

VVP:	112913564(ATAT1)

VLG:	121501255(ATAT1)

NPO:	129512610(ATAT1)

AML:	100473989(ATAT1)

UMR:	103664999(ATAT1)

UAH:	113264359(ATAT1)

UAR:	123794284(ATAT1)

ELK:

111152370

LLV:

125101805

MPUF:

101679281(ATAT1)

MNP:	132017752(ATAT1)

MLK:	131834419(ATAT1)

NVS:	122912100(ATAT1)

ORO:	101368740(ATAT1)

EJU:	114199234(ATAT1)

ZCA:	113926329(ATAT1)

MLX:	118027369(ATAT1)

NSU:	110578840 110586666(ATAT1)

LWW:

102741914

FCA:	101093356(ATAT1)

PYU:	121023110(ATAT1)

PCOO:

112853542(ATAT1)

PBG:	122489321(ATAT1)

PVIV:

125166683(ATAT1)

LRUF:

124528532

LGF:	123609562(ATAT1)

AJU:

106966611

PTG:	102966181(ATAT1)

PPAD:

109249510(ATAT1)

PUC:

125938492

PLEZ:

122219650(ATAT1)

HHV:	120222646(ATAT1)

BTA:	786491(ATAT1)

BOM:	102275558(ATAT1)

BIU:	109577111(ATAT1)

BBUB:

102405703(ATAT1)

BBIS:

104994570(ATAT1)

CHX:	102183555(ATAT1)

OAS:	101106803(ATAT1)

BTAX:

128056518(ATAT1)

CSUM:

138098077(ATAT1)

ODA:	120870501(ATAT1)

MREE:

136151450(ATAT1)

OVR:	110134371(ATAT1)

MBEZ:

129543149(ATAT1)

SSC:	100144480(ATAT1)

CFR:	102504889(ATAT1)

CBAI:

105074093(ATAT1)

CDK:	105087501(ATAT1) 116147121

VPC:	102534879(ATAT1)

BACU:

103016955(ATAT1)

BMUS:

118903640(ATAT1)

LVE:	103083275(ATAT1)

OOR:	101273516(ATAT1)

LALB:

132527528(ATAT1)

DLE:	111170678(ATAT1)

PCAD:

102974761(ATAT1)

PSIU:

116761964(ATAT1)

NASI:

112395449(ATAT1)

ECB:	100055595(ATAT1)

EPZ:	103567174(ATAT1)

EAI:	106825481(ATAT1)

MYB:	102240400(ATAT1)

MYD:	102762964(ATAT1)

MMYO:

118679502

MLF:	102437350(ATAT1)

MDT:	132237540(ATAT1)

MYUM:

139012743(ATAT1)

PKL:	118714058(ATAT1)

EFUS:

103300496(ATAT1)

MNA:	107538522(ATAT1)

DRO:	112302335(ATAT1)

SHON:

118987617(ATAT1)

AJM:	119046339(ATAT1)

PDIC:

114494485(ATAT1)

PHAS:

123810481(ATAT1)

MMF:	118620698(ATAT1)

PPAM:

129067287(ATAT1)

HAI:	109376104(ATAT1)

RFQ:	117020239(ATAT1)

PALE:

102879916(ATAT1)

PGIG:

120593370(ATAT1)

PVP:	105308145(ATAT1)

RAY:	107498064(ATAT1)

MJV:	108384338(ATAT1)

TOD:	119252107(ATAT1)

SARA:

101545003(ATAT1)

SFUM:

130035777(ATAT1)

SETR:

125996458(ATAT1)

LAV:	100664992(ATAT1)

TMU:

101361158

ETF:	101647457(ATAT1)

DNM:

101421604

MDO:	100024215(ATAT1)

GAS:	123245054(ATAT1)

SHR:	100919522(ATAT1)

AFZ:

127561043

PCW:	110199408(ATAT1)

TVP:	118856727(ATAT1)

PBRV:

138149943(ATAT1)

OAA:	103166272(ATAT1)

TACU:

119947040(ATAT1)

TGU:	115492253(ATAT1)

LSR:	110482313(ATAT1)

PMOA:

120503966

ATRC:

139586806(ATAT1)

PHI:	102104188(ATAT1)

CCAE:

111942560(ATAT1)

CBRC:

108448297(ATAT1)

ACOE:

138100776(ATAT1)

ZLE:	135460606(ATAT1)

SVG:	106863338(ATAT1)

CCIC:

134055832(ATAT1)

SHAB:

115618858(ATAT1)

ACHC:

115337893(ATAT1)

HLE:	104838035(ATAT1)

AGEN:

126034975

CBOY:

140644858(ATAT1)

CUCA:

128849593(ATAT1)

CRID:

134507887(ATAT1)

ASN:	102379630(ATAT1)

AMJ:	102573069(ATAT1)

PSS:	102444571(ATAT1)

CMY:	102941891(ATAT1)

CCAY:

125621589(ATAT1)

DCC:	119843044(ATAT1)

CPIC:

101936201(ATAT1)

TST:	117870426(ATAT1)

CABI:

116836708(ATAT1)

MRV:	120383876(ATAT1)

ACS:	100561358(atat1)

ASAO:

132765163(ATAT1)

PVT:	110089317(ATAT1)

SUND:

121920245(ATAT1)

PBI:	103048020 103064160

PMUR:

107297734(ATAT1)

CTIG:

120307286(ATAT1)

TSR:	106550119(ATAT1)

PGUT:

117667981(ATAT1)

APRI:

131193607(ATAT1)

PTEX:

113449636(ATAT1)

NSS:

113424281

VKO:	123019525(ATAT1)

PMUA:

114588270(ATAT1)

PRAF:

128408619(ATAT1)

ZVI:	118081085(ATAT1)

HCG:	128344382(ATAT1)

GJA:	107111806(ATAT1)

STOW:

125427701(ATAT1) 125427707

EMC:	129328088(ATAT1)

XLA:	734258(atat1.L) 735057(atat1.S)

XTR:	100038151(atat1)

NPR:	108790405(ATAT1)

RTEM:

120913493(ATAT1)

BBUF:

121009153(ATAT1)

BGAR:

122946163(ATAT1)

PWL:	138301453(ATAT1)

MUO:	115464949(ATAT1)

GSH:	117346803(ATAT1)

DRE:	406389(atat1)

SRX:	107711335 107754836

SANH:

107677465 107677472 107694337

SGH:	107584296 107595600

CCAR:

109063750 109063757

CAUA:

113090768 113119529

CGIB:

127935572 127979007

PTET:

122323438(atat1)

LROH:

127182024(atat1)

OMC:	131525523(atat1)

PPRM:

120485060(atat1)

RKG:	130087917(atat1)

MAMB:

125274767(atat1)

CIDE:

127500518

CERY:

137037710(atat1)

MASI:

127421051 127425466

TROS:

130566636(atat1)

TDW:	130415935(atat1)

MANU:

129454538(atat1)

PDAB:

135783373(atat1)

IPU:

108272794

IFU:	128615746(atat1)

PHYP:

113543803(atat1)

SMEO:

124381921(atat1)

TFD:	113634692(atat1)

TVC:	132842766(atat1)

CGAR:

128515539(atat1)

NGRA:

132870801(atat1)

TRN:	134328728(atat1)

AMEX:

103043739(atat1)

CMAO:

118805417(atat1)

EEE:	113590338(atat1)

CHAR:

105904694(atat1)

SPIL:

134073079(atat1)

TRU:	101074501 115251809(atat1)

TFS:	130517827(atat1)

TNG:	GSTEN00004688G001

LCO:	104931069(atat1)

NCC:

104951400

TBEN:

117477934(atat1)

CGOB:

115015403(atat1)

PGEO:

117455041(atat1)

GACU:

117535958(atat1)

EMAC:

134875163(atat1)

ELY:	117263696(atat1)

EFO:	125904576(atat1)

PLEP:

121957568(atat1)

SLUC:

116035741(atat1)

ECRA:

117957345(atat1)

ESP:	116701254(atat1)

PFLV:

114568380(atat1)

GAT:	120826705(atat1)

PPUG:

119218791(atat1)

AFB:	129097636(atat1)

CLUM:

117738580(atat1)

CANA:

137801722(atat1)

CVE:	137872537(atat1)

MSAM:

119907190(atat1)

SCHU:

122864202(atat1)

CUD:	121524078(atat1)

SPUL:

138609628(atat1)

LMIX:

132991703(atat1)

ALAT:

119016821(atat1)

ASTR:

137606958 137607123(atat1)

MZE:	101473057(atat1)

ONL:	100698811(atat1)

OAU:	116317007(atat1)

OLA:	101172832(atat1)

OML:	112137782(atat1)

CSAI:

133460526(atat1)

XMA:	102224331(atat1)

XCO:	114156469(atat1)

XHE:	116731875(atat1)

PRET:

103471914(atat1)

PFOR:

103142785(atat1)

PLAI:

106937899(atat1)

PMEI:

106912443(atat1)

GAF:	122843996(atat1)

PPRL:

129352762(atat1)

CVG:	107105221(atat1)

CTUL:

119784059(atat1)

GMU:	124879430(atat1)

NFU:	107383265(atat1)

KMR:	108248583(atat1)

ALIM:

106531007(atat1)

NWH:	119426110(atat1)

AOCE:

111575171(atat1)

EJA:	138214386(atat1)

BFRE:

138634046(atat1)

MCEP:

125019810(atat1)

CSEM:

103384383 103394495(atat1)

POV:	109643172(atat1)

SSEN:

122783133 122786311(atat1)

SSOE:

131445095 131447393(atat1)

HHIP:

117771129(atat1)

HSP:	118125029(atat1)

PPLT:

128461832(atat1)

LCF:

108896379

SDU:	111220869(atat1)

SLAL:

111645636(atat1)

XGL:	120786372(atat1)

HCQ:	109515158(atat1)

SBIA:

133507336(atat1)

PEE:	133395912(atat1)

PTAO:

133470948(atat1)

BPEC:

110161191(atat1)

ENY:	140361644(atat1)

MALB:

109974587(atat1)

BSPL:

114865643(atat1)

SJO:	128374746(atat1)

SSCO:

133996180(atat1)

GMH:	115535770(atat1)

SASA:

106570679 106589060(atat1)

STRU:

115174126 115175310(atat1)

OTW:	112238603 112247208

OMY:	110496896(atat1)

OGO:	124012771 124043077

ONE:	115116544 115125001

OKI:	109881871 109882165

OKE:	118378726 118380316(atat1)

OMM:	135549517 135551706

OCLA:

139372391 139392391 139403950

SALP:

111974506

SNH:	120021996(atat1) 120027367

CCLU:

121572234 121586834

ELS:	105012343(atat1)

OEP:	134040856(atat1)

SFM:	108935682(atat1)

PKI:	111842741(atat1)

AANG:

118234692(atat1)

AROT:

135262257(atat1)

CCOG:

133137325(atat1)

PSPA:

121298671(atat1)

ARUT:

117433594 117964778

PSEX:

120539678(atat1)

LCM:	102353700(ATAT1)

RTP:	109912442(atat1)

CPLA:

122541342(atat1)

HOC:	132832415(atat1)

LERI:

129694427(atat1)

BFO:

BBEL:

CIN:

SCLV:

SPU:	115929226 581275

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

SKO:

PFLL:

DME:	Dmel_CG17003(lky) Dmel_CG3967(Atat)

DER:	6545641 6550395

DSE:

6605026

DSI:	Dsimw501_GD12926(Dsim_GD12926) Dsimw501_GD15558(Dsim_GD15558)

DYA:	Dyak_GE17347 Dyak_GE21245

DAN:

6506373

DSR:	110184175 110190629

DPO:	6900997 6900998 6901295

DPE:	113566753 6598554 6599632

DMN:	108151967 108151969 108156830

DWI:	6638791 6644873

DGR:

6557341

DMO:	Dmoj_GI13265 Dmoj_GI14817

DAZ:	108613148 108618396

DNV:	108650490 108655956

DHE:	111602819 111603737

DVI:	6623141(Atat)

CCAT:

101451142 101452477

BOD:	106621507 106624106

BDR:

RZE:

AOQ:

ALUD:

TDA:

LCQ:

LSQ:

CVJ:	135953812(Atat)

GFS:

ECOE:

CLON:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ002083

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

TLN:

HST:

DQU:

CFO:

FEX:

PMEC:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

AROA:

TCA:

TMOL:

DPA:

ESIM:

EFOR:

SOY:

ATD:	109602224 109608541 109608563 109608617

AGB:

NVL:

PPYR:

BMOR:

BMAN:

MSEX:

DPL:	KGM_200100

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:	106113651 106113885

BPHI:

PRAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PGW:

LGLY:

CSTB:

CFEL:

113369258 113377702 113385498

CCRN:

123295394

API:	100162553 100168047 100169461 100570380 100570471 100570672 100575498

DNX:	107164488 107173589 107173592 107174168 107174192

AGS:	114123315 114123904 114132529 114132549 126551307

RMD:	113548079 113549333 113556182 113556835 113557143 113557201

ACOO:

126842722 126842723 126846216 126846402 126846710

DVT:	126894176 126903274 126903275

BTAB:

DCI:

CLEC:

HHAL:

NLU:	111050069 120349759

HVI:

124357217

MQU:	128994330 128994388 128995325 128995724 128995734 128995878

PHU:	Phum_PHUM581120

FOC:	113206970 113212172

TPAL:

ZNE:

CSEC:

PAME:

SGRE:

BROR:

IEL:

HAMR:

FCD:

DPX:	DAPPUDRAFT_304907

DMK:

DPZ:

AFRA:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

PTRU:

MRJ:

PORN:

EAF:

LSM:

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_F57H12.7(mec-17) CELE_W06B11.1(atat-2)

CBR:	CBG_14763(Cbr-atat-2) CBG_17726(Cbr-mec-17)

CRQ:	GCK72_014792 GCK72_024480

NAI:	NECAME_01566

BMY:	BM_BM6206(Bm6206)

LOA:	LOAG_13260

HRO:	HELRODRAFT_188468

LGI:	LOTGIDRAFT_109299 LOTGIDRAFT_148609

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:	111124186 111125721

OED:

MYI:

PMAX:

AIRR:

RPHI:

MAEA:

OBI:

OSN:

LJP:

LAK:	106151826 106173555

SMM:	Smp_166660

OVI:	T265_11140

EGL:

LLON:

NVE:

EPA:

ATEN:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_35009 TRIADDRAFT_53139

AQU:	100640763 105315491 109587786

SMO:	SELMODRAFT_420234

PPP:	112285127 112285208

VCN:	VOLCADRAFT_90683

MNG:

MNEG_1043

MIS:	MICPUN_85323

MPP:	MICPUCDRAFT_6581

RIE:	OCT59_026358

SRE:	PTSG_01905

PFD:	PFDG_01359

PFH:	PFHG_01378

PKN:	PKNH_0722800

PVX:	PVX_099660

PCY:	PCYB_073250

TET:	TTHERM_00355780

PTM:	GSPATT00035333001 GSPATT00035468001 GSPATT00036506001 GSPATT00037844001 GSPATT00038558001

NGD:	NGA_0112700

PIF:	PITG_13069

PSOJ:

PHYSODRAFT_347190

SPAR:

SPRG_08206

TBR:	Tb927.3.1400

TBG:	TbgDal_III1150

TCR:	467287.10 509233.160

LMA:	LMJF_25_1150

LIF:	LINJ_25_1190

LDO:	LDBPK_251190

LMI:	LMXM_25_1150

LMAT:

92515302(LSCM1_05319)

LBZ:	LBRM_25_1130

LPAN:

LPMP_251180

LOI:	92360386(LSCM4_04468)

LEIS:

94179773(GH5_04332)

LENR:

94172425(CUR178_05221)

LEIN:

94188182(JIQ42_04524)

NGR:	NAEGRDRAFT_58582

TVA:	4758203(TVAGG3_0307470) 4771043(TVAGG3_0166300)

GLA:	GL50803_0016348

SSAO:

94294444(SS50377_20421)

EHX:	EMIHUDRAFT_204370

GTT:	GUITHDRAFT_72899

» show all

Reference

PMID:20829795

Authors

Akella JS, Wloga D, Kim J, Starostina NG, Lyons-Abbott S, Morrissette NS, Dougan ST, Kipreos ET, Gaertig J

Title

MEC-17 is an alpha-tubulin acetyltransferase.

Journal

Nature 467:218-22 (2010)
DOI:10.1038/nature09324

Sequence

[hsa:79969] [cel:CELE_F57H12.7]

Reference

PMID:21068373

Authors

Shida T, Cueva JG, Xu Z, Goodman MB, Nachury MV

Title

The major alpha-tubulin K40 acetyltransferase alphaTAT1 promotes rapid ciliogenesis and efficient mechanosensation.

Journal

Proc Natl Acad Sci U S A 107:21517-22 (2010)
DOI:10.1073/pnas.1013728107

Sequence

[hsa:79969]

LinkDB

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