KEGG ORTHOLOGY: K19626

ORTHOLOGY: K19626

Entry

K19626                      KO

Symbol

INVS

Name

inversin

Pathway

map04310

Wnt signaling pathway

Disease

H00537

Nephronophthisis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K19626  INVS; inversin
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K19626  INVS; inversin
Cilium and associated proteins [BR:ko03037]
Primary cilia and associated proteins
  Nephronophthisis-related proteins
   K19626  INVS; inversin

Genes

HSA:	27130(INVS)

PTR:	473146(INVS)

PPS:	100988368(INVS)

GGO:	101134506(INVS)

PON:	100453593(INVS) 100454053

PPYG:

129024103 129044292(INVS)

NLE:	100594079(INVS)

HMH:	116475330(INVS)

SSYN:

129479099(INVS)

MCC:	714490(INVS)

MCF:	102136115(INVS)

MTHB:

126937765

MNI:	105480968(INVS)

CSAB:

103219130(INVS)

CATY:

105593031(INVS)

PANU:

101012572(INVS)

TGE:	112607816(INVS)

MLEU:

105532097

RRO:	104670789(INVS)

RBB:	108537165(INVS)

TFN:	117098915(INVS)

PTEH:

111536355(INVS)

CANG:

105518154

CJC:	100415162(INVS)

SBQ:	101033010(INVS)

CIMI:

108303865(INVS)

ANAN:

105706898(INVS)

CSYR:

103269694(INVS)

MMUR:

105873772(INVS)

LCAT:

123646451(INVS)

ERUF:

138387438(INVS)

PCOQ:

105805375(INVS)

OGA:	100954889(INVS)

MMU:	16348(Invs)

MCAL:

110292241(Invs)

MPAH:

110323300(Invs)

RNO:	313228(Invs)

MCOC:

116095992(Invs)

ANU:	117709230(Invs)

ASYL:

127680788(Invs)

MUN:	110558926(Invs)

CGE:	100750579(Invs)

MAUA:

101837715(Invs)

PROB:

127224685(Invs)

PLEU:

114702334(Invs)

PMAV:

102916377(Invs)

MORG:

121458519(Invs)

MFOT:

126509801

AAMP:

119826901(Invs)

CNL:	130888147(Invs)

NGI:	103749086(Invs)

HGL:	101711760(Invs)

CPOC:

100718120(Invs)

CCAN:

109688499(Invs)

DORD:

105990819(Invs)

DSP:	122121090(Invs)

DMER:

138819301(Invs)

PLOP:

125345974(Invs)

NCAR:

124964033

MMMA:

107147745(Invs)

ITI:	101972096(Invs)

OCU:

100344027

OPI:	101531956(INVS)

OCZ:	121172412(INVS)

TUP:	102484732(INVS)

GVR:	103603898(INVS)

CFA:	442950(INVS)

CLUD:

112650290(INVS)

VVP:	112930876(INVS)

VLG:	121494567(INVS)

NPO:	129494693(INVS)

AML:	100464110(INVS)

UMR:	103678515(INVS)

UAH:	113260392(INVS)

UAR:	123781047(INVS)

ELK:

111146079

LLV:

125083099

MPUF:

101693819(INVS)

MNP:	132024559(INVS)

MLK:	131813225(INVS)

NVS:	122917408(INVS)

ORO:	101381607(INVS)

EJU:	114213541(INVS)

ZCA:	113934348(INVS)

MLX:	118017886(INVS)

MANO:

123849226(INVS)

NSU:	110581466(INVS)

LWW:	102738596(INVS)

FCA:	101085078(INVS)

PYU:	121034745(INVS)

PCOO:

112848946(INVS)

PBG:	122475263(INVS)

PVIV:

125150283(INVS)

LRUF:

124502373

LGF:	123592579(INVS)

AJU:

106972062

PTG:	102971719(INVS)

PPAD:

109270071(INVS)

PUC:

125925978

PLEZ:

122205348(INVS)

HHV:	120248285(INVS)

CCRU:

144225012(INVS)

BTA:	529698(INVS)

BOM:	102277176(INVS)

BIU:	109563085(INVS)

BJV:	133252839(INVS)

BBUB:

102401568(INVS)

BKE:	129650314(INVS)

BBIS:

104993675(INVS)

CHX:	102176122(INVS)

OAS:	101122000(INVS)

OCAN:

138433413(INVS)

BTAX:

128052289(INVS)

CSUM:

138081361(INVS)

ODA:	120862885(INVS)

CCAD:

122452874(INVS)

MREE:

136148707(INVS)

OVR:	110152571(INVS)

MBEZ:

129556867(INVS)

SSC:	100155489(INVS)

CFR:	102521499(INVS)

CBAI:

105067397(INVS)

CDK:	105086912(INVS)

VPC:	102529567(INVS)

BACU:

103002299(INVS)

BMUS:

118896603(INVS)

LVE:	103069394(INVS)

OOR:	101283911(INVS)

LALB:

132523481(INVS)

GMF:	115838695(INVS)

DDP:	132427207(INVS)

DLE:	111188110(INVS)

PCAD:

102989995(INVS)

PSIU:

116755310(INVS)

PPHC:

136124237(INVS)

NASI:

112392625(INVS)

ECB:	100054700(INVS)

EPZ:	103549583(INVS)

EAI:	106831800(INVS)

MYB:	102260015(INVS)

MYD:	102765948(INVS)

MMYO:

118667252(INVS)

MLF:	102429019(INVS)

MDT:	132212201(INVS)

MYUM:

139020963(INVS)

PKL:	118716254(INVS)

EFUS:

103286391(INVS)

MNA:	107546579(INVS)

DRO:	112304478(INVS)

SHON:

118979631(INVS)

AJM:	119045942(INVS)

PDIC:

114491580(INVS)

PHAS:

123819674(INVS)

MMF:	118629426(INVS)

PPAM:

129079390(INVS)

HAI:	109386400(INVS)

RFQ:	117031786(INVS)

PALE:

102878310(INVS)

PGIG:

120597074(INVS)

PVP:

111728740

RAY:	107519679(INVS)

MJV:	108390410(INVS)

TOD:	119231877(INVS)

SARA:

101553206(INVS)

SFUM:

130026278(INVS)

SETR:

126003692(INVS)

LAV:	100672131(INVS)

TMU:

101359173

ETF:	101656207(INVS)

DNM:	111764971(INVS)

MDO:	100010929(INVS)

GAS:	123231963(INVS)

SHR:	100934498(INVS)

AFZ:

127541539

PCW:	110214555(INVS)

TVP:	118830734(INVS)

PBRV:

138175421(INVS)

MLAO:

141495430(INVS)

OAA:	100075447(INVS)

TACU:

119948850(INVS)

GGA:	395234(INVS)

PCOC:

116226270(INVS)

MGP:	100550331(INVS) 104910204

CJO:	107309918(INVS)

TPAI:

128091157(INVS)

LMUT:

125691250(INVS)

NMEL:

110395096(INVS)

APLA:

101795550(INVS)

AACU:

137850829(INVS)

OJA:	118163318(INVS)

ACYG:

106035993(INVS)

CATA:

118250024(INVS)

AFUL:

116485768(INVS)

TGU:	100222496(INVS)

LSR:	110469691(INVS)

VMC:	128821326(INVS)

VCHA:

128796219(INVS)

AIB:	137476200(INVS)

SCAN:

103826098(INVS)

PMOA:

120502999(INVS)

OTC:	121337829(INVS)

PRUF:

121358482(INVS)

ATRC:

139604654(INVS)

MATE:

118698348(INVS)

MAEN:

136563443(INVS)

GFR:	102031933(INVS)

FAB:	101813338(INVS)

OMA:	130249752(INVS)

PHI:	102104378(INVS)

PMAJ:

107199690(INVS)

CCAE:

111925287(INVS)

CCW:	104685820(INVS)

CBRC:

103623571(INVS)

ACOE:

138104917(INVS)

ETL:	114058930(INVS)

ZAB:	102066065(INVS)

ZLE:	135444278(INVS)

ACHL:

103805639(INVS)

SVG:	106852494(INVS)

MMEA:

130574866(INVS)

HRT:	120754875(INVS)

SATI:

136366630(INVS)

CFAI:

136290391(INVS)

CCIC:

134048616(INVS)

FPG:	101920337(INVS)

FCH:	102050888(INVS)

FRS:	119145615(INVS)

CCRI:

104160549

NNT:	104406748(INVS)

SHAB:

115618346(INVS)

POCC:

134158713(INVS)

ACUN:

113476991(INVS)

ANOC:

141957591(INVS)

SURA:

141946544(INVS)

TALA:

104365434(INVS)

ACHC:

115340266(INVS)

HALD:

104310603

HLE:	104838298(INVS)

AGEN:

126051188

HHAR:

128142464(INVS)

BBUT:

142028876(INVS)

GCL:

127012812

CSTI:

104558494(INVS)

LDI:	104347246(INVS)

MNB:	103777552(INVS)

DPUB:

104296855(INVS)

PPUS:

135178818(INVS)

IIN:	128967627(INVS)

AVIT:

104279543

BRHI:

104501450(INVS)

EGZ:	104130443(INVS)

NNI:	104018201(INVS)

PCAO:

104043419(INVS)

PARX:

142053212(INVS)

PADL:

103917734(INVS)

AFOR:

103896750(INVS)

FGA:	104083383(INVS)

CBOR:

142078932(INVS)

GSTE:

104255246

CBOY:

140647820(INVS)

MAME:

142405971(INVS)

CLV:	102095274(INVS)

CNIC:

135984906(INVS)

PGUU:

104469695

PLET:

104623338(INVS)

EHS:	104510421(INVS)

CMAC:

104481139(INVS)

CUCA:

104062177(INVS)

PCUR:

138718770(INVS)

TEO:	104379897(INVS)

BREG:

104629651

GAME:

129202117(INVS)

OHA:	104335552(INVS)

ACAR:

104520510(INVS)

CPEA:

104385210(INVS)

CVF:	104287210(INVS)

RTD:	128904987(INVS)

CRID:

134511812(INVS)

LMIC:

141739355(INVS)

NARQ:

141463776(INVS)

AAM:	106496963(INVS)

AROW:

112974898(INVS)

NPD:	112951476(INVS)

TGT:	104572457(INVS)

DNE:	112988250(INVS)

SCAM:

104148971(INVS)

ASN:	102367837 102380671(INVS)

AMJ:	102560593(INVS)

CPOO:

109313373(INVS)

GGN:	109291924(INVS)

PSS:	102461761(INVS)

CIZ:	142009629(INVS)

CMY:	102933425(INVS)

CCAY:

125631930(INVS)

LKP:	140907177(INVS)

NDS:	141982778(INVS)

DCC:	119850489(INVS)

CPIC:

101940197(INVS)

TST:	117872694(INVS)

EOB:	135874426(INVS)

CABI:

116828734(INVS)

MRV:	120398071(INVS)

EMQ:	137167615(INVS)

ACS:	100566170(invs)

ASAO:

132778489(INVS)

PVT:

110085769

SUND:

121935262(INVS)

PBI:	103062207(INVS)

PMUR:

107284062(INVS)

CTIG:

120298196(INVS)

TSR:	106538043(INVS)

PGUT:

117664931(INVS)

APRI:

131197046(INVS)

PTEX:

113437383(INVS)

NSS:	113419098(INVS)

VKO:	123035084(INVS)

PMUA:

114581705(INVS)

PRAF:

128400645(INVS)

ZVI:	118094161(INVS)

HCG:	128330261(INVS)

GJA:	107112855(INVS)

STOW:

125440552(INVS)

EMC:	129337680(INVS)

XLA:	378491(invs.S) 398717(invs.L)

XTR:	100487895(invs)

NPR:	108791353(INVS)

RTEM:

120914603

ACAT:

141108617(INVS)

PADS:

140344463(INVS)

BBUF:

121009138(INVS)

BGAR:

122946399(INVS)

DTC:	141101677(INVS)

PWL:	138299169(INVS)

MUO:	115471409(INVS)

GSH:	117353564(INVS)

DRE:	245946(invS)

DAES:

130243706(invs)

SRX:	107706121 107723456

SANH:

107657729 107689904

SGH:	107593695 107596027

CCAR:

109104931(invs)

CAUA:

113059849(invs)

CGIB:

128030626

PTET:

122360433(invs)

LROH:

127179014(invs)

GRF:	141342776(invs)

OMC:	131522408(invs)

PPRM:

120484328(invs)

RKG:	130084223(invs)

MAMB:

125242964(invs)

CIDE:

127497588

CERY:

137034922(invs)

MASI:

127452994

TROS:

130557442(invs)

TDW:	130432638(invs)

MANU:

129448071(invs)

PDAB:

135743227(invs)

IPU:

108256412

IFU:	128599899(invs)

PHYP:

113533056(invs)

SMEO:

124403831(invs)

TFD:	113659316(invs)

TVC:	132840000(invs)

CGAR:

128513902(invs)

NGRA:

132867333(invs)

TRN:	134300871(invs)

AMEX:

103026533(invs)

CMAO:

118798614(invs)

EEE:	113567952 113590838(invs)

CHAR:

105893955(invs)

SPIL:

134083298(invs)

ASAD:

121720324(invs)

TRU:	101070892(invs)

TFS:	130533207(invs)

TNG:	GSTEN00034032G001

LCO:	104923026(invs)

NCC:

104952997

TBEN:

117480373(invs)

CGOB:

115020764(invs)

PGEO:

117460873(invs)

GACU:

117553982(invs)

EMAC:

134862146(invs)

ELY:	117265797(invs)

EFO:	125893659(invs)

PLEP:

121945440

SLUC:

116049478(invs)

ECRA:

117946405(invs)

ESP:	116691617(invs)

PFLV:

114557572(invs)

GAT:	120810890(invs)

PPUG:

119198162(invs)

AFB:	129109381(invs)

CLUM:

117745073(invs)

PSWI:

130212793(invs)

CANA:

137780945(invs)

CVE:	137891486(invs)

MSAM:

119897665(invs)

SCHU:

122881899(invs)

EARM:

139290455(invs)

CUD:	121513285(invs)

SPUL:

138584313(invs)

LMIX:

132983978(invs)

HTC:	141801431(invs)

ALAT:

119005602(invs)

ASTR:

137602032(invs)

PKLU:

139205193(invs)

MZE:	101482273(invs)

ONL:	100692462(invs)

OAU:	116331368(invs)

OLA:	101168237(invs)

OML:	112143201(invs)

CSAI:

133441001(invs)

XMA:	102226426(invs)

XCO:	114141643(invs)

XHE:	116717666(invs)

PRET:

103478654(invs)

PFOR:

103140867(invs)

PLAI:

106945870(invs)

PMEI:

106923147(invs)

GAF:	122831604(invs)

PPRL:

129371266(invs)

CVG:	107082124(invs)

CTUL:

119787280(invs)

GMU:	124865402(invs)

NFU:	107379726(invs)

KMR:	108241157(invs)

ALIM:

106515106(invs)

NWH:	119409418(invs)

LTU:	140316479(invs)

AOCE:

111577815(invs)

EJA:	138194268(invs)

BFRE:

138619512(invs)

MCEP:

125016315(invS)

CSEM:

103388142(invs)

POV:	109633387(invs)

SSEN:

122764068(invs)

SSOE:

131471159(invs)

HHIP:

117777243(invs)

HSP:	118113583(invs)

PPLT:

128449457(invs)

SMAU:

118311725(invs)

LCF:

108889603

SDU:	111236923(invs)

SLAL:

111650849(invs)

XGL:	120783800(invs)

HCQ:	109528997(invs)

SSCV:

125975354(invs)

SBIA:

133500480(invs)

PEE:	133401635(invs)

PTAO:

133478992(invs)

BPEC:

110171540(invs)

ENY:	140373929(invs)

MALB:

109964089(invs)

BSPL:

114842514(invs)

SJO:	128367117(invs)

SSCO:

133983167(invs)

TTY:	137191475(invs)

GMH:	115553503(invs)

SASA:

106593616(invs) 106605926

STRU:

115180994 115181004

OTW:

112222496

OMY:	110534148 110535632

OGO:	123998307 124017028

ONE:	115126885(invs)

OKI:	109883489(invs) 116356745

OKE:	118376519 118382091

OMM:	135520790(invs) 135521708

OCLA:

139387726 139420365

SALP:

112072885(invs)

SNH:	120030987(invs) 120039642

SFON:

129838129 129857023(invs)

CCLU:

121543893(invs)

ELS:	105018949(invs)

OEP:	134023740(invs)

SFM:	108940671(invs)

PKI:	111845557(invs)

AANG:

118207020(invs)

AROT:

135257238(invs)

CCOG:

133117892(invs)

LOC:	102691030(invs)

PSPA:

121314683(invs)

ARUT:

117394706(invs)

PSEX:

120516049(invs)

LCM:	102346790(INVS) 102353332

CMK:	103181166(invs)

RTP:	109914041(invs)

CPLA:

122549865(invs)

CPUN:

140480556(invs)

HOC:	132815717(invs)

SCAU:

119966253(invs)

LERI:

129713813(invs)

HAKA:

140732107(invs)

PMRN:

116938650(INVS)

LRJ:	133345991(INVS)

BFO:

BBEL:

CIN:

SCLV:

CLEP:

SPU:	115926637 589721

LPIC:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

IEL:

EAF:

TCF:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

PTRU:

SPRM:

ESN:

MNZ:	135221980 135221981

MRJ:

PORN:

DALB:

RSAN:

CSCU:

ABRU:

UDV:

SDM:

LPOL:

PVUL:

PCAN:

LSAX:

BARL:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

YBA:

MCAF:

127710421 127718071 127736586

MMER:

123539137

RPHI:

132750860 132751176

DPOL:

127847285 127847286 127847622 127848196

MAEA:

OBI:

OSN:

LJP:

LAK:

LLON:

NVE:	116601545 5516650

EPA:

110241812

ATEN:

116307580

ADF:	107341827 107344404

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

AQU:	105312727 105316553 109582743

CCLM:

134193596 134196705

MBR:	MONBRDRAFT_7731

SRE:	PTSG_03687 PTSG_05580 PTSG_08810 PTSG_12654 PTSG_12949

TAN:

TA05515

TPV:

TP03_0180

» show all

Reference

PMID:22206729

Authors

Lienkamp S, Ganner A, Walz G

Title

Inversin, Wnt signaling and primary cilia.

Journal

Differentiation 83:S49-55 (2012)
DOI:10.1016/j.diff.2011.11.012

Reference

PMID:20798123

Authors

Bellavia S, Dahan K, Terryn S, Cosyns JP, Devuyst O, Pirson Y

Title

A homozygous mutation in INVS causing juvenile nephronophthisis with abnormal reactivity of the Wnt/beta-catenin pathway.

Journal

Nephrol Dial Transplant 25:4097-102 (2010)
DOI:10.1093/ndt/gfq519

Sequence

[hsa:27130]

LinkDB

DBGET integrated database retrieval system