KEGG   ORTHOLOGY: K19700
Entry
K19700                      KO                                     
Symbol
sap
Name
3-succinoylsemialdehyde-pyridine dehydrogenase [EC:1.2.1.83]
Pathway
map00760  Nicotinate and nicotinamide metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Module
M00811  Nicotine degradation, pyrrolidine pathway, nicotine => succinate semialdehyde
Reaction
R10105  4-oxo-4-(pyridin-3-yl)butanal:NADP+ oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    K19700  sap; 3-succinoylsemialdehyde-pyridine dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.83  3-succinoylsemialdehyde-pyridine dehydrogenase
     K19700  sap; 3-succinoylsemialdehyde-pyridine dehydrogenase
Other DBs
COG: COG1012
Genes
PPT: PPS_4079
PMON: X969_19985
PMOT: X970_19620
PMED: E3Z27_20795
PVK: EPZ47_21945
PSJY: AA098_04090
ALCA: ASALC70_03936(ald_1)
GSO: PH603_02990
AG: AFD54464(sap)
Reference
PMID:22267672
  Authors
Qiu J, Ma Y, Wen Y, Chen L, Wu L, Liu W
  Title
Functional identification of two novel genes from Pseudomonas sp. strain HZN6 involved in the catabolism of nicotine.
  Journal
Appl Environ Microbiol 78:2154-60 (2012)
DOI:10.1128/AEM.07025-11
  Sequence
[ag:AFD54464]
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