KEGG   ORTHOLOGY: K19884
Entry
K19884            Tight     KO                                     
Symbol
rebO
Name
7-chloro-L-tryptophan oxidase [EC:1.4.3.23]
Pathway
map00404  Staurosporine biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00789  Rebeccamycin biosynthesis, tryptophan => rebeccamycin
Reaction
R09560  7-chloro-L-tryptophan:oxygen oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00404 Staurosporine biosynthesis
    K19884  rebO; 7-chloro-L-tryptophan oxidase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.4  Acting on the CH-NH2 group of donors
   1.4.3  With oxygen as acceptor
    1.4.3.23  7-chloro-L-tryptophan oxidase
     K19884  rebO; 7-chloro-L-tryptophan oxidase
Other DBs
COG: COG1231
Genes
AG: BAC10674(rebO)
Reference
  Authors
Nishizawa T, Aldrich CC, Sherman DH
  Title
Molecular analysis of the rebeccamycin L-amino acid oxidase from Lechevalieria aerocolonigenes ATCC 39243.
  Journal
J Bacteriol 187:2084-92 (2005)
DOI:10.1128/JB.187.6.2084-2092.2005
  Sequence
Reference
  Authors
Howard-Jones AR, Walsh CT
  Title
Enzymatic generation of the chromopyrrolic acid scaffold of rebeccamycin by the tandem action of RebO and RebD.
  Journal
Biochemistry 44:15652-63 (2005)
DOI:10.1021/bi051706e
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