KEGG   ORTHOLOGY: K19889
Entry
K19889            Tight     KO                                     
Symbol
rebM
Name
demethylrebeccamycin-D-glucose O-methyltransferase [EC:2.1.1.164]
Pathway
map00404  Staurosporine biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00789  Rebeccamycin biosynthesis, tryptophan => rebeccamycin
Reaction
R09569  S-adenosyl-L-methionine:demethylrebeccamycin-D-glucose O-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00404 Staurosporine biosynthesis
    K19889  rebM; demethylrebeccamycin-D-glucose O-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.164  demethylrebeccamycin-D-glucose O-methyltransferase
     K19889  rebM; demethylrebeccamycin-D-glucose O-methyltransferase
Genes
AG: BAC10678(rebM)
Reference
  Authors
Singh S, McCoy JG, Zhang C, Bingman CA, Phillips GN Jr, Thorson JS
  Title
Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM.
  Journal
J Biol Chem 283:22628-36 (2008)
DOI:10.1074/jbc.M800503200
  Sequence
LinkDB

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