KEGG ORTHOLOGY: K20187

ORTHOLOGY: K20187

Entry

K20187                      KO

Symbol

BLOC1S5

Name

biogenesis of lysosome-related organelles complex 1 subunit 5

Disease

H00166

Hermansky-Pudlak syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K20187  BLOC1S5; biogenesis of lysosome-related organelles complex 1 subunit 5
Membrane trafficking [BR:ko04131]
Endosome - Lysosome transport
  Others
   BLOC-1 complex
    K20187  BLOC1S5; biogenesis of lysosome-related organelles complex 1 subunit 5

Other DBs

GO:

0031083

Genes

HSA:	63915(BLOC1S5)

PTR:	463205(BLOC1S5)

PPS:	100977762(BLOC1S5)

GGO:	101128471(BLOC1S5)

PON:	100935874(BLOC1S5)

NLE:	100586417(BLOC1S5)

HMH:	116460205(BLOC1S5)

MCC:	100423337(BLOC1S5)

MCF:	102141303(BLOC1S5)

MTHB:

126952665

MNI:	105487399(BLOC1S5)

CSAB:

103222203(BLOC1S5)

CATY:

105572506(BLOC1S5)

PANU:

101014023(BLOC1S5)

TGE:	112623446(BLOC1S5)

MLEU:

105546439(BLOC1S5)

RRO:	104676815(BLOC1S5)

RBB:	108534324(BLOC1S5)

TFN:	117086700(BLOC1S5)

PTEH:

111548615(BLOC1S5)

CANG:

105526617(BLOC1S5)

CJC:	100395062(BLOC1S5)

SBQ:	101035455(BLOC1S5)

CIMI:

108302979(BLOC1S5)

CSYR:

103261082(BLOC1S5)

MMUR:

105865175(BLOC1S5)

LCAT:

123638241(BLOC1S5)

PCOQ:

105806490(BLOC1S5)

OGA:	100955446(BLOC1S5)

MMU:	17828(Bloc1s5)

MCAL:

110308250(Bloc1s5)

MPAH:

110334046(Bloc1s5)

RNO:	306868(Bloc1s5)

MCOC:

116081909(Bloc1s5)

ANU:	117714395(Bloc1s5)

MUN:	110546343(Bloc1s5)

CGE:	100766796(Bloc1s5)

MAUA:

101825377(Bloc1s5)

PROB:

127229326(Bloc1s5)

PLEU:

114710562(Bloc1s5)

MORG:

121433913(Bloc1s5)

MFOT:

126501865

AAMP:

119817732(Bloc1s5)

NGI:	103732903(Bloc1s5)

HGL:	101706841(Bloc1s5)

CPOC:

100721323(Bloc1s5)

CCAN:

109698166(Bloc1s5)

DORD:

105985959(Bloc1s5)

DSP:	122114044(Bloc1s5)

PLOP:

125353045(Bloc1s5)

NCAR:

124988392

MMMA:

107149235(Bloc1s5)

OCU:	100354613 127482726

OPI:	101526450(BLOC1S5)

TUP:	102491220(BLOC1S5)

GVR:	103605565(BLOC1S5)

CFA:	609473(BLOC1S5)

CLUD:

112658622(BLOC1S5)

VVP:	112920557(BLOC1S5)

VLG:	121500838(BLOC1S5)

NPO:	129507476(BLOC1S5)

AML:	100478045(BLOC1S5)

UMR:	103664932(BLOC1S5)

UAH:	113264433(BLOC1S5)

UAR:	123801485(BLOC1S5)

ELK:

111156702

LLV:

125102884

MPUF:

101677195(BLOC1S5)

MNP:	132017591(BLOC1S5)

MLK:	131834509(BLOC1S5)

NVS:	122912636(BLOC1S5)

ORO:	101366110(BLOC1S5)

EJU:	114223919(BLOC1S5)

ZCA:	113927712(BLOC1S5)

MLX:	118027442(BLOC1S5)

NSU:	110586707(BLOC1S5)

LWW:	102728587(BLOC1S5)

FCA:	101098141(BLOC1S5)

PYU:	121020586(BLOC1S5)

PCOO:

112853504(BLOC1S5)

PBG:	122489253(BLOC1S5) 122489350

PVIV:

125166169(BLOC1S5)

LRUF:

124528663

PTG:	102950709(BLOC1S5)

PPAD:

109249417(BLOC1S5)

PUC:

125939589

AJU:

106971810

HHV:	120246804(BLOC1S5)

BTA:	505520(BLOC1S5)

BOM:	102269508(BLOC1S5)

BIU:	109554850(BLOC1S5)

BBUB:

102410208(BLOC1S5)

BBIS:

104985609(BLOC1S5)

CHX:	102180273(BLOC1S5)

OAS:	101107314(BLOC1S5)

BTAX:

128056201(BLOC1S5) 128069511

ODA:	120865856 120869993(BLOC1S5)

CCAD:

122429348(BLOC1S5)

MBEZ:

129543217

SSC:	100049677(BLOC1S5)

CFR:	102505965(BLOC1S5)

CBAI:

105061629(BLOC1S5)

CDK:	105100691(BLOC1S5)

VPC:	102531979(BLOC1S5)

BMUS:

118904161(BLOC1S5)

LVE:	103087590(BLOC1S5)

OOR:	101272547(BLOC1S5)

DLE:	111173617 111181346(BLOC1S5)

PCAD:

102977595 102984810(BLOC1S5)

PSIU:

116762587(BLOC1S5)

NASI:

112398088(BLOC1S5)

ECB:	100051053(BLOC1S5)

EPZ:	103549318(BLOC1S5)

EAI:	106832086(BLOC1S5)

MYB:	102254881(BLOC1S5)

MYD:	102755833(BLOC1S5)

MMYO:

118676385(BLOC1S5)

MLF:	102419766(BLOC1S5)

PKL:	118722294(BLOC1S5)

EFUS:

103290193(BLOC1S5)

MNA:	107529130(BLOC1S5)

DRO:	112297540(BLOC1S5)

SHON:

118986434(BLOC1S5)

AJM:	119046620(BLOC1S5)

PDIC:

114497448(BLOC1S5)

PHAS:

123820764(BLOC1S5)

MMF:	118626641(BLOC1S5) 118631237

PPAM:

129085530(BLOC1S5)

HAI:	109395511(BLOC1S5)

RFQ:	117027816(BLOC1S5) 117034179

PALE:

102878729(BLOC1S5)

PGIG:

120607667(BLOC1S5)

PVP:	105296752(BLOC1S5)

RAY:	107507204(BLOC1S5)

MJV:	108404309(BLOC1S5)

TOD:	119251592(BLOC1S5) 119256519

SARA:

101544295(BLOC1S5)

SETR:

125996249(BLOC1S5)

LAV:	100660031(BLOC1S5)

TMU:

101354476

ETF:	101655276(BLOC1S5)

DNM:	101427280(BLOC1S5)

MDO:	100020375(BLOC1S5)

GAS:	123240334(BLOC1S5)

SHR:	100929035(BLOC1S5)

AFZ:

127544188

PCW:	110224066(BLOC1S5)

OAA:	100083741(BLOC1S5)

GGA:	420866(BLOC1S5)

PCOC:

116226440(BLOC1S5)

MGP:	100540269(BLOC1S5)

CJO:	107309658(BLOC1S5)

TPAI:

128087914(BLOC1S5)

LMUT:

125690909(BLOC1S5)

NMEL:

110394691(BLOC1S5)

APLA:

101804541(BLOC1S5)

ACYG:

106034870(BLOC1S5)

CATA:

118254773(BLOC1S5)

AFUL:

116486247(BLOC1S5)

TGU:	100227726(BLOC1S5)

LSR:	110472659(BLOC1S5)

SCAN:

103815133(BLOC1S5)

PMOA:

120503550(BLOC1S5)

OTC:	121340469(BLOC1S5)

PRUF:

121357806(BLOC1S5)

GFR:	102041978(BLOC1S5)

OMA:	130249227(BLOC1S5)

PHI:	102108152(BLOC1S5)

PMAJ:

107200864(BLOC1S5)

CCAE:

111923935(BLOC1S5)

CCW:	104691382(BLOC1S5)

CBRC:

103624242(BLOC1S5)

ETL:	114065664(BLOC1S5)

ZAB:	102073796(BLOC1S5)

ACHL:

103800377(BLOC1S5)

SVG:	106858926(BLOC1S5)

MMEA:

130575306(BLOC1S5)

HRT:	120760417(BLOC1S5)

FPG:	101914115(BLOC1S5)

FCH:	102056991(BLOC1S5)

CLV:	102086740(BLOC1S5)

EGZ:	104127704(BLOC1S5)

NNI:	104021900(BLOC1S5)

PCRI:

104030048(BLOC1S5)

PLET:

104621506

ACUN:

113476049(BLOC1S5)

TALA:

104365840(BLOC1S5)

PADL:

103919081(BLOC1S5)

AFOR:

103898854(BLOC1S5)

ACHC:

115352991(BLOC1S5)

HALD:

104312077

HLE:	104835315(BLOC1S5)

AGEN:

126048751

GCL:

127012797

CCRI:

104155746(BLOC1S5)

CSTI:

104558894

CMAC:

104481292(BLOC1S5)

MUI:	104537634(BLOC1S5)

FGA:

104076911

GSTE:

104258302

LDI:	104345266(BLOC1S5)

MNB:	103782445(BLOC1S5)

OHA:	104326767(BLOC1S5)

NNT:	104412065(BLOC1S5)

SHAB:

115605246(BLOC1S5)

DPUB:

104308915(BLOC1S5)

PGUU:

104472090(BLOC1S5)

ACAR:

104519302(BLOC1S5)

CPEA:

104391651(BLOC1S5)

AVIT:

104280223

CVF:	104286793(BLOC1S5)

RTD:	128905386(BLOC1S5)

CUCA:

104062147(BLOC1S5)

TEO:	104384442(BLOC1S5)

BRHI:

104501313

AAM:	106500439(BLOC1S5)

AROW:

112969493(BLOC1S5)

NPD:	112947291(BLOC1S5)

TGT:	104573068(BLOC1S5)

DNE:	112992007(BLOC1S5)

ASN:	102377579(BLOC1S5)

AMJ:	102567933(BLOC1S5)

CPOO:

109315406(BLOC1S5)

GGN:	109301296(BLOC1S5)

PSS:	102448063(BLOC1S5)

CMY:	102931168(BLOC1S5)

CCAY:

125632124(BLOC1S5)

DCC:	119851578(BLOC1S5)

CPIC:

101933184(BLOC1S5)

TST:	117873192(BLOC1S5)

CABI:

116818027(BLOC1S5)

MRV:	120398766(BLOC1S5)

ACS:	100557237(bloc1s5)

ASAO:

132774579(BLOC1S5)

PVT:	110080869(BLOC1S5)

SUND:

121929277(BLOC1S5)

PBI:	103060782(BLOC1S5)

PMUR:

107282993(BLOC1S5)

CTIG:

120311099(BLOC1S5)

TSR:	106543119(BLOC1S5)

PGUT:

117672470(BLOC1S5)

APRI:

131194624

PTEX:

113445706(BLOC1S5)

NSS:	113418025(BLOC1S5)

VKO:	123036385(BLOC1S5)

PMUA:

114600918(BLOC1S5)

PRAF:

128417790(BLOC1S5)

ZVI:	118090454(BLOC1S5)

HCG:	128324679(BLOC1S5)

GJA:	107112942(BLOC1S5)

STOW:

125439285(BLOC1S5)

XLA:	100037008(bloc1s5.L)

XTR:	100101667(bloc1s5)

NPR:	108790132(BLOC1S5)

RTEM:

120940701(BLOC1S5)

BBUF:

121001164(BLOC1S5)

BGAR:

122938628(BLOC1S5)

MUO:	115473838(BLOC1S5)

GSH:	117355740(BLOC1S5)

DRE:	324781(bloc1s5)

SRX:	107730006 107742256(bloc1s5)

SANH:

107664638 107678529(bloc1s5)

SGH:	107550015(bloc1s5) 107572672

CCAR:

109075472 109075473

CAUA:

113042188(bloc1s5)

CGIB:

128013500

PTET:

122329424(bloc1s5)

LROH:

127155362(bloc1s5)

OMC:	131533251(bloc1s5)

PPRM:

120475826(bloc1s5)

RKG:	130084395(bloc1s5)

MAMB:

125245028 125258259(bloc1s5)

CIDE:

127506477

MASI:

127431873 127434205

TROS:

130547123(bloc1s5)

TDW:	130412848(bloc1s5)

MANU:

129426471(bloc1s5)

IPU:

108256219

IFU:	128599892(bloc1s5)

PHYP:

113532528(bloc1s5)

SMEO:

124403708(bloc1s5)

TFD:	113659664(bloc1s5)

TVC:	132840482(bloc1s5)

AMEX:

103029882(bloc1s5)

CMAO:

118800445(bloc1s5)

EEE:	113579558(bloc1s5)

CHAR:

105890269(bloc1s5)

TRU:	101079673(bloc1s5)

TFS:	130513721(bloc1s5)

TNG:	GSTEN00010402G001

LCO:	109136781(bloc1s5)

NCC:	104953926(bloc1s5)

TBEN:

117483892(bloc1s5)

CGOB:

115025501(bloc1s5)

PGEO:

117465726(bloc1s5)

GACU:

117543642(bloc1s5)

EMAC:

134883745(bloc1s5)

ELY:	117264496(bloc1s5)

EFO:	125881565(bloc1s5)

PLEP:

121960570(bloc1s5)

SLUC:

116046272(bloc1s5)

ECRA:

117938203(bloc1s5)

ESP:	116672190(bloc1s5)

PFLV:

114549252(bloc1s5)

GAT:	120811944(bloc1s5)

PPUG:

119198943(bloc1s5)

AFB:	129110977(bloc1s5)

CLUM:

117749931(bloc1s5)

PSWI:

130206195(bloc1s5)

MSAM:

119908039(bloc1s5)

SCHU:

122866935(bloc1s5)

CUD:	121527677(bloc1s5)

ALAT:

119008940(bloc1s5)

MZE:	101476696(bloc1s5)

ONL:	100694853(bloc1s5)

OAU:	116332550(bloc1s5)

OLA:	101160365(bloc1s5)

OML:	112150999(bloc1s5)

CSAI:

133423084(bloc1s5)

XMA:	102227751(bloc1s5)

XCO:	114136390(bloc1s5)

XHE:	116711569(bloc1s5)

PRET:

103482502(bloc1s5)

PFOR:

103135284(bloc1s5)

PLAI:

106963902(bloc1s5)

PMEI:

106907555(bloc1s5)

GAF:	122824014(bloc1s5) 122824015 122824673

PPRL:

129364657(bloc1s5)

CVG:	107094066(bloc1s5)

CTUL:

119784597(bloc1s5)

GMU:	124857668(bloc1s5)

NFU:	107383028(bloc1s5)

KMR:	108243998(bloc1s5)

ALIM:

106517540(bloc1s5)

NWH:	119426304(bloc1s5)

AOCE:

111589150(bloc1s5)

MCEP:

124996020(bloc1s5)

CSEM:

103376946(bloc1s5)

POV:	109629659(bloc1s5)

SSEN:

122781724(bloc1s5)

HHIP:

117754113(bloc1s5)

HSP:	118098895(bloc1s5)

SMAU:

118291380(bloc1s5)

LCF:

108884010

SDU:	111237219(bloc1s5)

SLAL:

111657375(bloc1s5) 111660512

XGL:	120789592(bloc1s5)

HCQ:	109519177(bloc1s5)

SSCV:

125985761

SBIA:

133492520(bloc1s5)

PEE:	133396470(bloc1s5)

PTAO:

133470206(bloc1s5)

BPEC:

110161011(bloc1s5)

MALB:

109968788(bloc1s5)

BSPL:

114854188(bloc1s5)

SJO:	128382680(bloc1s5)

SASA:

106590249(bloc1s5)

STRU:

115195597(bloc1s5)

OTW:	112227802(bloc1s5)

OMY:	110489761(bloc1s5)

OGO:	124039153(bloc1s5)

ONE:	115130219(bloc1s5)

OKI:	109899339(bloc1s5)

OKE:	118371345(bloc1s5)

SALP:

111953615(bloc1s5)

SNH:	120028075 120050363(bloc1s5)

CCLU:

121549681 121570443

ELS:	105019527(bloc1s5)

SFM:	108927578(bloc1s5)

PKI:	111840815(bloc1s5)

AANG:

118226626(bloc1s5)

LOC:	102694363(bloc1s5)

PSPA:

121313057(bloc1s5)

ARUT:

117399655(bloc1s5)

PSEX:

120529841(bloc1s5)

LCM:	102352960(BLOC1S5)

CMK:	103185075(bloc1s5)

RTP:	109930108(bloc1s5)

CPLA:

122549195(bloc1s5)

HOC:	132815373(bloc1s5)

LERI:

129696679(bloc1s5)

PMRN:

116946613(BLOC1S5)

LRJ:	133352950(BLOC1S5)

BFO:

BBEL:

LPIC:

APLC:

SKO:

DME:	Dmel_CG34131(Muted)

DER:

26526538

DSE:

6607403

DSI:	Dsimw501_GD20937(Dsim_GD20937)

DYA:	Dyak_GE10287

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI10477

DAZ:

DNV:

DHE:

DVI:

CCAT:

BDR:

AOQ:

TDA:	119679613 119683447

MDE:

LCQ:

LSQ:

GFS:

CNS:

AME:

ALAB:

BIM:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PFUC:

VPS:

VCRB:

VVE:

CSOL:

TPRE:

LHT:

LBD:

MDL:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

NVL:

APLN:

PPYR:

BMOR:

BMAN:

BANY:

MJU:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

TNL:

SLIU:

PGW:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

DCI:

NLU:

HVI:

TPAL:

ZNE:

CSEC:

BROR:

IEL:

FCD:

DMK:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

EAF:

TCF:

PPOI:

DSV:

RSAN:

RMP:

TUT:

CSCU:

PTEP:

ABRU:

SDM:

LPOL:

HRO:	HELRODRAFT_162130

LGI:	LOTGIDRAFT_202237

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MMER:

RPHI:

DPOL:

127845731 127845732 127848688 127854963

OBI:

OSN:

LAK:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:	114525073 114540974

XEN:

124451882

HMG:

101235404

HSY:

130629730

TAD:	TRIADDRAFT_61049

AQU:

105312285

» show all

Reference

PMID:17182842

Authors

Setty SR, Tenza D, Truschel ST, Chou E, Sviderskaya EV, Theos AC, Lamoreux ML, Di Pietro SM, Starcevic M, Bennett DC, Dell'Angelica EC, Raposo G, Marks MS

Title

BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles.

Journal

Mol Biol Cell 18:768-80 (2007)
DOI:10.1091/mbc.E06-12-1066

Sequence

[hsa:63915]

LinkDB

DBGET integrated database retrieval system