KEGG ORTHOLOGY: K20188

ORTHOLOGY: K20188

Entry

K20188                      KO

Symbol

BLOC1S6

Name

biogenesis of lysosome-related organelles complex 1 subunit 6

Disease

H00166

Hermansky-Pudlak syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K20188  BLOC1S6; biogenesis of lysosome-related organelles complex 1 subunit 6
Membrane trafficking [BR:ko04131]
Endosome - Lysosome transport
  Others
   BLOC-1 complex
    K20188  BLOC1S6; biogenesis of lysosome-related organelles complex 1 subunit 6

Other DBs

GO:

0031083

Genes

HSA:	26258(BLOC1S6)

PTR:	100615120(BLOC1S6)

PPS:	100984422(BLOC1S6)

GGO:	101142607(BLOC1S6)

PON:	100453142(BLOC1S6)

PPYG:

129013929(BLOC1S6)

NLE:	100599479(BLOC1S6)

HMH:	116482634(BLOC1S6)

SSYN:

129482729(BLOC1S6)

MCC:	713569(BLOC1S6)

MCF:	101866235(BLOC1S6)

MTHB:

126959012

MNI:	105490953(BLOC1S6)

CSAB:

103245692(BLOC1S6)

CATY:

105588188(BLOC1S6)

PANU:

101006309(BLOC1S6)

TGE:	112627465(BLOC1S6)

MLEU:

105548198(BLOC1S6)

RRO:	104674036(BLOC1S6)

RBB:	108530121(BLOC1S6)

TFN:	117070712(BLOC1S6)

PTEH:

111552742(BLOC1S6)

CANG:

105502170(BLOC1S6)

CJC:	100409884(BLOC1S6)

SBQ:	101040129(BLOC1S6)

CIMI:

108315807(BLOC1S6)

ANAN:

105710042(BLOC1S6)

CSYR:

103271192(BLOC1S6)

MMUR:

105872564(BLOC1S6)

LCAT:

123622222(BLOC1S6)

PCOQ:

105814469(BLOC1S6)

OGA:	100954716(BLOC1S6)

MMU:	18457(Bloc1s6)

MCAL:

110288485(Bloc1s6)

MPAH:

110319333(Bloc1s6)

RNO:	317630(Bloc1s6)

MCOC:

116090832(Bloc1s6)

ANU:	117704111(Bloc1s6)

ASYL:

127685831(Bloc1s6)

MUN:	110553261(Bloc1s6)

CGE:	100771201(Bloc1s6)

MAUA:

101823718(Bloc1s6)

PROB:

127221533(Bloc1s6)

PLEU:

114699612(Bloc1s6)

MORG:

121465613(Bloc1s6)

MFOT:

126496568

AAMP:

119814788(Bloc1s6)

NGI:	103746986(Bloc1s6)

HGL:	101707035(Bloc1s6)

CPOC:

100735197(Bloc1s6)

CCAN:

109676806(Bloc1s6)

DORD:

105981161(Bloc1s6)

DSP:	122114513(Bloc1s6)

PLOP:

125340351(Bloc1s6)

NCAR:

124978068 124978075

MMMA:

107138127(Bloc1s6)

ITI:	101969247(Bloc1s6)

OCU:

100354374

OPI:	101525640(BLOC1S6)

TUP:	102492316(BLOC1S6)

GVR:	103600769(BLOC1S6)

CFA:	478288(BLOC1S6)

CLUD:

112675989(BLOC1S6)

VVP:	112920033(BLOC1S6)

VLG:	121484046(BLOC1S6)

NPO:	129504218(BLOC1S6)

AML:	100467020(BLOC1S6)

UMR:	103656584(BLOC1S6)

UAH:	113269575(BLOC1S6)

UAR:	123801948(BLOC1S6)

ELK:

111160190

LLV:

125103894

MPUF:

101680558(BLOC1S6)

MNP:	131999725(BLOC1S6)

MLK:	131836236(BLOC1S6)

NVS:	122893266(BLOC1S6)

ORO:	101362857(BLOC1S6)

ZCA:	113910515(BLOC1S6)

MLX:	118003467(BLOC1S6)

NSU:	110585217(BLOC1S6)

LWW:	102749699(BLOC1S6)

FCA:	101089617(BLOC1S6)

PYU:	121041649(BLOC1S6)

PCOO:

112856226(BLOC1S6)

PBG:	122468688(BLOC1S6)

PVIV:

125167523(BLOC1S6)

LRUF:

124508616

LGF:	123583074(BLOC1S6)

AJU:

106986282

PTG:	102969843(BLOC1S6)

PPAD:

109263036(BLOC1S6)

PLEZ:

122222082(BLOC1S6)

HHV:	120243828(BLOC1S6)

BTA:	614408(BLOC1S6)

BOM:	102273093(BLOC1S6)

BIU:	109565158(BLOC1S6)

BBUB:

102408289(BLOC1S6)

BBIS:

104994240(BLOC1S6)

CHX:	102183796(BLOC1S6)

OAS:	101113763(BLOC1S6)

BTAX:

128053842(BLOC1S6)

CSUM:

138073205(BLOC1S6)

ODA:	120852947(BLOC1S6)

CCAD:

122443643(BLOC1S6)

MREE:

136172260(BLOC1S6)

OVR:	110150075(BLOC1S6)

MBEZ:

129562986(BLOC1S6)

SSC:	100049678(BLOC1S6)

CFR:	102506585(BLOC1S6)

CBAI:

105076996(BLOC1S6)

CDK:	105104958(BLOC1S6)

VPC:	102545434(BLOC1S6)

BACU:

103018632(BLOC1S6)

BMUS:

118890164(BLOC1S6)

LVE:	103075036(BLOC1S6)

OOR:	101282599(BLOC1S6)

LALB:

132520605(BLOC1S6)

DLE:	111181634(BLOC1S6)

PCAD:

102993733(BLOC1S6)

PSIU:

116748414(BLOC1S6)

NASI:

112410640(BLOC1S6)

ECB:	100060806 111767411(BLOC1S6)

EPZ:	103554022(BLOC1S6) 139078012

EAI:	106834986(BLOC1S6) 106840341

MYB:	102240777(BLOC1S6)

MYD:	102770074(BLOC1S6)

MMYO:

118651366(BLOC1S6)

MLF:	102436023(BLOC1S6)

MDT:	132237725(BLOC1S6)

MYUM:

139015768(BLOC1S6)

PKL:	118721919(BLOC1S6)

EFUS:

103287397(BLOC1S6)

MNA:	107535746(BLOC1S6)

DRO:	112311876(BLOC1S6)

SHON:

118992587(BLOC1S6)

AJM:	119057629(BLOC1S6)

PDIC:

114493280(BLOC1S6)

PHAS:

123808664(BLOC1S6)

MMF:	118615371(BLOC1S6)

PPAM:

129064275(BLOC1S6)

HAI:	109396651(BLOC1S6)

RFQ:	117023983(BLOC1S6)

PALE:

102893275(BLOC1S6)

PGIG:

120622684(BLOC1S6)

PVP:	105288723(BLOC1S6)

RAY:	107514963(BLOC1S6)

TOD:	119238585(BLOC1S6)

SARA:

101546550(BLOC1S6)

SFUM:

130043065(BLOC1S6)

SETR:

126020911(BLOC1S6)

LAV:	100675698(BLOC1S6)

TMU:

101352566

ETF:	101651488(BLOC1S6)

DNM:	101425387(BLOC1S6)

MDO:	100013484(BLOC1S6)

GAS:	123237874(BLOC1S6)

SHR:	100934913(BLOC1S6)

AFZ:

127549345

PCW:	110223655(BLOC1S6)

TVP:	118829220(BLOC1S6)

PBRV:

138175495(BLOC1S6)

OAA:	100076406(BLOC1S6)

TACU:

119946052(BLOC1S6)

GGA:	415447(BLOC1S6)

PCOC:

116225328(BLOC1S6)

MGP:	100542182(BLOC1S6)

CJO:	107318742(BLOC1S6)

TPAI:

128075568(BLOC1S6)

LMUT:

125698107(BLOC1S6)

NMEL:

110404058(BLOC1S6)

APLA:

101794548(BLOC1S6)

ACYG:

106033609(BLOC1S6)

CATA:

118251551(BLOC1S6)

AFUL:

116493672(BLOC1S6)

TGU:	100226487(BLOC1S6)

LSR:	110474255(BLOC1S6)

SCAN:

103816193(BLOC1S6)

PMOA:

120508921(BLOC1S6)

OTC:	121343573(BLOC1S6)

PRUF:

121354496(BLOC1S6)

ATRC:

139596851(BLOC1S6)

GFR:	102040198(BLOC1S6)

FAB:	101808864(BLOC1S6)

OMA:	130257300(BLOC1S6)

PHI:	102100476(BLOC1S6)

PMAJ:

107209457(BLOC1S6)

CCAE:

111933881(BLOC1S6)

CCW:	104684104(BLOC1S6)

CBRC:

103621328(BLOC1S6)

ACOE:

138116674(BLOC1S6)

ETL:	114059948(BLOC1S6)

ZAB:	102063821(BLOC1S6)

ZLE:	135452467(BLOC1S6)

ACHL:

103802576(BLOC1S6)

SVG:	106860053(BLOC1S6)

MMEA:

130575782(BLOC1S6)

HRT:	120758970(BLOC1S6)

SATI:

136367043(BLOC1S6)

CCIC:

134049263(BLOC1S6)

FPG:	101915346(BLOC1S6)

FCH:	102055538(BLOC1S6)

CCRI:

104159538(BLOC1S6)

NNT:	104400784(BLOC1S6)

SHAB:

115613099(BLOC1S6)

ACUN:

113484005(BLOC1S6)

TALA:

104356427(BLOC1S6)

ACHC:

115341498(BLOC1S6)

HALD:

104323285(BLOC1S6)

HLE:	104834511(BLOC1S6)

AGEN:

126044119

HHAR:

128150966(BLOC1S6)

GCL:

127020847

CSTI:

104551748(BLOC1S6)

LDI:	104341488(BLOC1S6)

MNB:	103775403(BLOC1S6)

DPUB:

104297383(BLOC1S6)

PPUS:

135182994(BLOC1S6)

AVIT:

104269301(BLOC1S6)

BRHI:

104489997(BLOC1S6)

EGZ:	104130791(BLOC1S6)

NNI:	104017262(BLOC1S6)

PCRI:

104026183(BLOC1S6)

PCAO:

104049185(BLOC1S6)

PADL:

103922787(BLOC1S6)

AFOR:

103896705(BLOC1S6)

FGA:	104071430(BLOC1S6)

GSTE:

104252631(BLOC1S6)

CBOY:

140655851(BLOC1S6)

CLV:	102085832(BLOC1S6)

MUI:	104539764(BLOC1S6)

PGUU:

104459874(BLOC1S6)

PLET:

104615496(BLOC1S6)

EHS:	104504745(BLOC1S6)

CMAC:

104474819(BLOC1S6)

CUCA:

104055745(BLOC1S6)

TEO:	104371212(BLOC1S6)

BREG:

104630990(BLOC1S6)

OHA:	104334637(BLOC1S6)

ACAR:

104521747(BLOC1S6)

CPEA:

104386023(BLOC1S6)

CVF:	104287464(BLOC1S6)

RTD:	128914592(BLOC1S6)

CRID:

134521066(BLOC1S6)

AAM:	106496402(BLOC1S6)

AROW:

112963527(BLOC1S6)

NPD:	112952872(BLOC1S6)

TGT:	104567429(BLOC1S6)

DNE:	112995971(BLOC1S6)

SCAM:

104148408(BLOC1S6)

ASN:	102372905(BLOC1S6)

AMJ:	102570847(BLOC1S6)

CPOO:

109309057(BLOC1S6)

GGN:	109288577(BLOC1S6)

PSS:	102450590(BLOC1S6)

CMY:	102937293(BLOC1S6)

CCAY:

125643899(BLOC1S6)

DCC:	119862883(BLOC1S6)

CPIC:

101943150(BLOC1S6)

TST:	117883952(BLOC1S6)

CABI:

116830916(BLOC1S6)

MRV:	120374018(BLOC1S6)

ASAO:

132762352(BLOC1S6)

PVT:	110077266(BLOC1S6)

SUND:

121933410(BLOC1S6)

PBI:	112540507(BLOC1S6)

PMUR:

107300699(BLOC1S6)

CTIG:

120315133(BLOC1S6)

PGUT:

117675731(BLOC1S6)

APRI:

131184807(BLOC1S6)

PTEX:

113442406(BLOC1S6)

NSS:	113418283(BLOC1S6)

VKO:	123027666(BLOC1S6)

PMUA:

114584151(BLOC1S6)

PRAF:

128401737(BLOC1S6)

ZVI:	118093195(BLOC1S6)

HCG:	128334983(BLOC1S6)

GJA:	107124457(BLOC1S6)

STOW:

125446134(BLOC1S6)

EMC:	129345854(BLOC1S6)

XLA:	108711404 734279(bloc1s6.S)

XTR:	549256(bloc1s6)

NPR:	108796987(BLOC1S6)

RTEM:

120931312(BLOC1S6)

BBUF:

120985844(BLOC1S6)

BGAR:

122927614(BLOC1S6)

PWL:	138284098(BLOC1S6)

MUO:	115459798 115459800

GSH:	117348454(BLOC1S6)

DRE:	791215(bloc1s6)

SRX:	107710813 107713042(bloc1s6)

SANH:

107663466 107690137(bloc1s6)

SGH:	107595357(bloc1s6)

CCAR:

109064163(bloc1s6)

CAUA:

113061339(bloc1s6)

CGIB:

127934134 128021954

PTET:

122362537(bloc1s6)

LROH:

127157446(bloc1s6)

OMC:	131524465(bloc1s6)

PPRM:

120484860(bloc1s6)

RKG:	130077521(bloc1s6)

MAMB:

125254617(bloc1s6)

CIDE:

127499804

CERY:

137023003(bloc1s6)

MASI:

127416792 127455942

TDW:	130417158 130435299(bloc1s6)

MANU:

129419243(bloc1s6)

PDAB:

135739874 135773935

IPU:

108264504

IFU:	128607156(bloc1s6)

SMEO:

124395609(bloc1s6)

TFD:	113650483(bloc1s6)

TVC:	132851540(bloc1s6)

CGAR:

128527532(bloc1s6)

NGRA:

132888228(bloc1s6)

TRN:	134323230(bloc1s6)

AMEX:

103023901(bloc1s6)

CMAO:

118803972(bloc1s6)

EEE:	113585350(bloc1s6)

CHAR:

122130284(bloc1s6)

SPIL:

134095226(bloc1s6)

TRU:	101079755(bloc1s6)

TFS:	130514416(bloc1s6)

TNG:	GSTEN00018090G001

LCO:	104930534(bloc1s6)

NCC:	104951147(bloc1s6)

TBEN:

117471201(bloc1s6)

CGOB:

115026274(bloc1s6)

PGEO:

117464885(bloc1s6)

GACU:

117549388(bloc1s6)

EMAC:

134863247(bloc1s6)

ELY:	117253189(bloc1s6)

EFO:	125880391(bloc1s6)

PLEP:

121947072(bloc1s6)

SLUC:

116054591(bloc1s6)

ECRA:

117942803(bloc1s6)

ESP:	116705510(bloc1s6)

PFLV:

114552975(bloc1s6)

GAT:	120835521(bloc1s6)

PPUG:

119199555(bloc1s6)

AFB:	129099943(bloc1s6)

CLUM:

117749477(bloc1s6)

PSWI:

130192822(bloc1s6)

CANA:

137781964(bloc1s6)

CVE:	137888704(bloc1s6)

MSAM:

119890058(bloc1s6)

SCHU:

122873040(bloc1s6)

CUD:	121511397(bloc1s6)

SPUL:

138588428(bloc1s6)

LMIX:

132964865(bloc1s6)

ALAT:

119017866(bloc1s6)

ASTR:

137593368(bloc1s6)

MZE:	101477614(bloc1s6)

ONL:	100693914(bloc1s6)

OAU:	116311638(bloc1s6)

OLA:	101172565(bloc1s6)

OML:	112160894(bloc1s6)

CSAI:

133459741(bloc1s6)

XMA:	102233834(bloc1s6)

XCO:	114143529(bloc1s6)

XHE:	116718946(bloc1s6)

PRET:

103462092(bloc1s6)

PFOR:

103146164(bloc1s6)

PLAI:

106934395(bloc1s6)

PMEI:

106924770(bloc1s6)

GAF:	122841562(bloc1s6)

PPRL:

129369582(bloc1s6)

CVG:	107085370(bloc1s6)

CTUL:

119782436(bloc1s6)

GMU:	124866758(bloc1s6)

NFU:	107381734(bloc1s6)

KMR:	108251192(bloc1s6)

ALIM:

106532966(bloc1s6)

NWH:	119429544(bloc1s6)

AOCE:

111565742(bloc1s6)

EJA:	138212912(bloc1s6)

BFRE:

138625023(bloc1s6)

MCEP:

125005297(bloc1s6)

CSEM:

103379091(bloc1s6)

POV:	109637273(bloc1s6)

SSEN:

122772894(bloc1s6)

SSOE:

131459620(bloc1s6)

HHIP:

117755534(bloc1s6)

HSP:	118112352(bloc1s6)

PPLT:

128447636(bloc1s6)

SMAU:

118302490(bloc1s6)

LCF:

108887890

SDU:	111238641(bloc1s6)

SLAL:

111661146(bloc1s6)

XGL:	120789706(bloc1s6)

HCQ:	109525882(bloc1s6)

SSCV:

125967752(bloc1s6)

SBIA:

133497728(bloc1s6)

PEE:	133399359(bloc1s6)

PTAO:

133467005(bloc1s6)

BPEC:

110172879(bloc1s6)

ENY:	140381009(bloc1s6)

MALB:

109963343(bloc1s6)

BSPL:

114843169(bloc1s6)

SJO:	128357485(bloc1s6)

SSCO:

133985278(bloc1s6)

GMH:	115558297(bloc1s6)

SASA:

106562462(PLDN) 106562500(PLDN) 106587685(PLDN)

STRU:

115166967 115203346

OTW:	112248022(bloc1s6)

OMY:	100301760(pldn) 110518754

OGO:	124033533(bloc1s6)

ONE:	115119358(bloc1s6)

OKI:	109881714(bloc1s6)

OKE:	118381697(bloc1s6)

OMM:	135556731(bloc1s6)

OCLA:

139411646

SALP:

111969546(bloc1s6)

SNH:	120025006(bloc1s6)

CCLU:

121579858(bloc1s6)

ELS:	105022654(bloc1s6)

OEP:	134028478(bloc1s6)

SFM:	108942061(bloc1s6)

PKI:	111846666(bloc1s6)

AANG:

118227082(bloc1s6)

AROT:

135255399(bloc1s6)

CCOG:

133130653(bloc1s6)

LOC:	102683170(bloc1s6)

PSPA:

121294593(bloc1s6)

ARUT:

117428183 117429279

PSEX:

120541331(bloc1s6)

LCM:	102345479(BLOC1S6)

CMK:	103186590(bloc1s6)

RTP:	109911875(bloc1s6)

HOC:	132834243(bloc1s6)

LERI:

129712687(bloc1s6)

PMRN:

116955755(BLOC1S6)

BFO:

BBEL:

CIN:

SCLV:

SPU:	115919024 762368

LPIC:

AJJ:

APLC:

AAMU:

AFIL:

SKO:

PFLL:

DME:	Dmel_CG14133(Pldn)

DER:

6544570

DSE:

6605317

DSI:	Dsimw501_GD12785(Dsim_GD12785)

DYA:	Dyak_GE20189

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI11582

DAZ:

108613637

DNV:

108651884

DHE:

111592788

DVI:	6623642(Pldn)

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:

MDE:	101895098 131806353

SCAC:

106082933

LCQ:

111687023

LSQ:

119600235

CVJ:	135954052(Pldn)

GFS:

ECOE:

CLON:

AGA:

ACOZ:

AARA:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ020225

CPII:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

139109570(Pldn)

TLN:	139823092(Pldn)

HST:

105189514

DQU:

106743009

CFO:

105249057

PMEC:

138933396(Pldn)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124215933(Pldn)

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

ESIM:

136410875(Pldn)

EFOR:

136344875(Pldn)

SOY:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_209875

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137925617(Pldn)

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106692818(Pldn)

NLU:

111053675

HVI:

124368844

MQU:	128998207 128998217

PHU:	Phum_PHUM602260

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138706737(Pldn)

SGRE:

126297888

BROR:

134539526

IEL:

124169029

HAMR:

139697426(Pldn)

FCD:

110847162

DPX:	DAPPUDRAFT_231329

DMK:	116920994 123472558

DPZ:

124337562

PVM:	113800793(Pldn)

PJA:

PCHN:

PMOO:

HAME:

CQD:

PTRU:

ESN:

MNZ:	135225773 135225797

MRJ:	136839517(Pldn)

PORN:

139760899(Pldn)

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

DPTE:

DFR:

CSCU:

CVS:	136978665(Pldn)

ABRU:

UDV:

SDM:

LPOL:

LGI:	LOTGIDRAFT_105900

PCAN:

112556203

LSAX:

138950162

BGT:	106075465 106079112

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:	111111093 111116745

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

LLON:

NVE:

EPA:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_60322

» show all

Reference

PMID:17182842

Authors

Setty SR, Tenza D, Truschel ST, Chou E, Sviderskaya EV, Theos AC, Lamoreux ML, Di Pietro SM, Starcevic M, Bennett DC, Dell'Angelica EC, Raposo G, Marks MS

Title

BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles.

Journal

Mol Biol Cell 18:768-80 (2007)
DOI:10.1091/mbc.E06-12-1066

Sequence

[hsa:26258]

LinkDB

DBGET integrated database retrieval system