KEGG ORTHOLOGY: K20351

ORTHOLOGY: K20351

Entry

K20351                      KO

Symbol

TMED6

Name

p24 family protein gamma-5

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K20351  TMED6; p24 family protein gamma-5
Membrane trafficking [BR:ko04131]
Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   p24 family proteins
    K20351  TMED6; p24 family protein gamma-5

Other DBs

TC:

9.B.188

Genes

HSA:	146456(TMED6)

PTR:	744308(TMED6)

PPS:	100980401(TMED6)

GGO:	101148046(TMED6)

PON:	100432826(TMED6)

PPYG:

129015687(TMED6)

NLE:	100600803(TMED6)

HMH:	116471443(TMED6)

SSYN:

129492569(TMED6)

MCC:	704771(TMED6)

MCF:	102118712(TMED6)

MTHB:

126944099

MNI:	105491355(TMED6)

CSAB:

103233213(TMED6)

CATY:

105581268(TMED6)

PANU:

101009085(TMED6)

TGE:	112614438(TMED6)

MLEU:

105537175(TMED6)

RRO:	104655877(TMED6)

RBB:	108514503(TMED6)

TFN:	117087971(TMED6)

PTEH:

111541406(TMED6)

CANG:

105504526(TMED6)

CJC:	100402679(TMED6)

SBQ:	101039760(TMED6)

CIMI:

108311769(TMED6)

ANAN:

105706776(TMED6)

CSYR:

103272543(TMED6)

MMUR:

105858970(TMED6)

LCAT:

123625156(TMED6)

PCOQ:

105823381(TMED6)

OGA:	100946624(TMED6)

MMU:	66269(Tmed6)

MCAL:

110300905(Tmed6)

MPAH:

110337299(Tmed6)

RNO:	291991(Tmed6)

MCOC:

116070115(Tmed6)

ANU:	117723353(Tmed6)

ASYL:

127671674(Tmed6)

MUN:	110546099(Tmed6)

CGE:	100760131(Tmed6)

MAUA:

121136313(Tmed6)

PROB:

127234496(Tmed6)

PLEU:

114683441(Tmed6)

MORG:

121446710(Tmed6)

MFOT:

126502996

AAMP:

119802252(Tmed6)

NGI:	103734743(Tmed6)

HGL:	101715666(Tmed6)

CPOC:

100723830(Tmed6)

CCAN:

109693767(Tmed6)

DORD:

105983038(Tmed6)

DSP:	122126192(Tmed6)

PLOP:

125358247(Tmed6)

NCAR:

124967488

MMMA:

107150949(Tmed6)

ITI:	101971871(Tmed6)

OCU:	100339894 127491366

OPI:	101531174(TMED6)

TUP:	102491643(TMED6)

GVR:	103586585(TMED6)

CFA:	610951(TMED6)

CLUD:

112646553(TMED6)

VVP:	112929470(TMED6)

VLG:	121500327(TMED6)

NPO:	129497046(TMED6)

AML:	100474052(TMED6)

UMR:	103673615(TMED6)

UAH:	113252429(TMED6)

UAR:	123803528(TMED6)

ELK:

111152781

LLV:

125089364

MPUF:

101683905(TMED6)

MNP:	132005377(TMED6)

MLK:	131818408(TMED6)

NVS:	122911295(TMED6)

ORO:	101371333(TMED6)

EJU:	114201687(TMED6)

ZCA:	113935989(TMED6)

MLX:	118023624(TMED6)

NSU:	110592337(TMED6)

LWW:	102725873(TMED6)

FCA:	101097195(TMED6)

PYU:	121009719(TMED6)

PCOO:

112857492(TMED6)

PBG:	122494396(TMED6)

PVIV:

125153055(TMED6)

LRUF:

124511440

LGF:	123579374(TMED6)

AJU:

106972114

PTG:	102955261(TMED6)

PPAD:

109270704(TMED6)

PUC:

125916300

PLEZ:

122209113(TMED6)

HHV:	120223807(TMED6)

BTA:	533277(TMED6)

BOM:	102281709(TMED6)

BIU:	109571989(TMED6)

BBUB:

102395475(TMED6)

BBIS:

104996652(TMED6)

CHX:	102172570(TMED6)

OAS:	101121367(TMED6)

BTAX:

128063345(TMED6) 128071123

CSUM:

138096172(TMED6)

ODA:	120872693(TMED6)

CCAD:

122420300(TMED6)

MREE:

136161123(TMED6)

OVR:	110129642(TMED6)

MBEZ:

129546957(TMED6)

SSC:	100517589(TMED6)

CFR:	102515921(TMED6)

CBAI:

105074874(TMED6)

CDK:	105088398(TMED6)

VPC:	102542606(TMED6)

BACU:

103002105(TMED6)

BMUS:

118884984(TMED6)

LVE:	103070889(TMED6)

OOR:	101269227(TMED6)

LALB:

132510427(TMED6)

DLE:	111179585(TMED6)

PCAD:

102977816(TMED6)

PSIU:

116743581(TMED6)

NASI:

112411780(TMED6)

ECB:	100054050(TMED6)

EPZ:	103563763(TMED6)

EAI:	106822463(TMED6)

MYB:	102240797(TMED6)

MYD:	102766727(TMED6)

MMYO:

118674523(TMED6)

MLF:	102433582(TMED6)

MDT:	132217413(TMED6)

MYUM:

138996855(TMED6)

PKL:	118720928(TMED6)

EFUS:

103284624(TMED6)

MNA:	107527908(TMED6)

DRO:	112300790(TMED6)

SHON:

118983803(TMED6)

AJM:	119061878(TMED6)

PDIC:

114488247(TMED6)

PHAS:

123805802(TMED6)

MMF:	118638686(TMED6)

PPAM:

129075238(TMED6)

HAI:	109389252(TMED6)

RFQ:	117035558(TMED6)

PALE:

102888404(TMED6)

PGIG:

120593917(TMED6)

PVP:	105307202(TMED6)

RAY:	107520725(TMED6)

MJV:	108405298(TMED6)

TOD:	119249004(TMED6)

SARA:

101545537(TMED6)

SFUM:

130044523(TMED6)

SETR:

126027442(TMED6)

LAV:	100661846(TMED6)

TMU:

101349564

ETF:	101656063(TMED6)

DNM:	101415625(TMED6)

MDO:	100028032(TMED6)

GAS:	123234588(TMED6)

SHR:	100915991(TMED6)

AFZ:

127547741

PCW:	110210256(TMED6)

TVP:	118841836(TMED6)

PBRV:

138159278(TMED6)

OAA:	100079153(TMED6)

TACU:

119934801(TMED6)

GGA:	101750075(TMED6)

PCOC:

116243698(TMED6)

MGP:	100547949(TMED6)

CJO:	107319483(TMED6)

TPAI:

128081978(TMED6)

LMUT:

125699259(TMED6)

NMEL:

110404179(TMED6)

APLA:

119718131(TMED6)

ACYG:

106046631(TMED6)

CATA:

118257878(TMED6)

AFUL:

116493824(TMED6)

TGU:	100223840(TMED6)

LSR:	110468814(TMED6)

SCAN:

103816772(TMED6)

PMOA:

120496212(TMED6)

OTC:	121333776(TMED6)

PRUF:

121362382(TMED6)

ATRC:

139596539(TMED6)

GFR:	102044808(TMED6)

FAB:	101821465(TMED6)

OMA:	130257646(TMED6)

PHI:	102105212(TMED6)

PMAJ:

107209943(TMED6)

CCAE:

111934385(TMED6)

CCW:	104691952(TMED6)

CBRC:

103620536(TMED6)

ACOE:

138117141(TMED6)

ETL:	114068306(TMED6)

ZAB:	102070915(TMED6)

ZLE:	135452767(TMED6)

ACHL:

103799215(TMED6)

SVG:	106861282(TMED6)

MMEA:

130584793(TMED6)

HRT:	120757864(TMED6)

SATI:

136366380(TMED6)

CCIC:

134048511(TMED6)

FPG:	101912738(TMED6)

FCH:	102049962(TMED6)

CCRI:

104157421(TMED6)

NNT:	104402274(TMED6)

ACUN:

113484640(TMED6)

TALA:

104365295(TMED6)

ACHC:

115346359(TMED6)

HALD:

104316478(TMED6)

HLE:	104839318(TMED6)

AGEN:

126040231

HHAR:

128145789(TMED6)

GCL:

127021291

CSTI:

104554028(TMED6)

LDI:	104340140(TMED6)

MNB:	103772466(TMED6)

DPUB:

104303810(TMED6)

PPUS:

135184435(TMED6)

AVIT:

104273228

BRHI:

104497135(TMED6)

EGZ:	104129693(TMED6)

NNI:	104023560(TMED6)

PCRI:

104037647(TMED6)

PCAO:

104052108(TMED6)

AFOR:

103907303(TMED6)

FGA:	104072640(TMED6)

GSTE:

104260756(TMED6)

CBOY:

140657132(TMED6)

CLV:	102094846(TMED6)

MUI:	104533182(TMED6)

PGUU:

104457707(TMED6)

PLET:

104627245(TMED6)

EHS:	104502870(TMED6)

CUCA:

104054987(TMED6)

TEO:	104378931(TMED6)

OHA:	104330244(TMED6)

ACAR:

104517890(TMED6)

CPEA:

104398330(TMED6)

CVF:	104294430(TMED6)

RTD:	128908540(TMED6)

CRID:

134515679(TMED6)

AROW:

112971739(TMED6)

NPD:	112947522(TMED6)

TGT:	104577252(TMED6)

DNE:	112994434(TMED6)

SCAM:

104151927(TMED6)

ASN:	102372736(TMED6)

AMJ:	102563467(TMED6)

CPOO:

109310742(TMED6)

GGN:	109289362(TMED6)

PSS:	102452561(TMED6)

CMY:	102931315(TMED6)

CCAY:

125645317(TMED6)

DCC:	119841392(TMED6)

CPIC:

101949986(TMED6)

TST:	117886837(TMED6)

CABI:

116819576(TMED6)

MRV:	120384186(TMED6)

ACS:	100560744(tmed6)

ASAO:

132782973(TMED6)

PVT:	110076297(TMED6)

PBI:	103055705(TMED6)

PMUR:

107283548(TMED6)

CTIG:

120302486(TMED6)

TSR:	106555897(TMED6)

PGUT:

117671061(TMED6)

APRI:

131184370(TMED6)

PTEX:

113448931(TMED6)

NSS:	113423431(TMED6)

VKO:	123022181(TMED6)

PMUA:

114602078(TMED6)

PRAF:

128419326(TMED6)

ZVI:	118086482(TMED6)

HCG:	128334200(TMED6)

GJA:	107106557(TMED6)

STOW:

125443886(TMED6)

EMC:	129344296(TMED6)

XLA:	108714065(tmed6.L) 108715089(tmed6.S)

XTR:	496652(tmed6)

NPR:	108798647(TMED6)

RTEM:

120917962(TMED6)

BBUF:

120980539(TMED6)

BGAR:

122920557(TMED6)

PWL:	138267820(TMED6)

MUO:	115459193 115470992(TMED6)

DRE:	101884766(tmed6)

SRX:	107723965 107750000 107754984

SANH:

107677821(tmed6) 107688864

SGH:	107572224 107574411 107579002

CCAR:

109072885 109083685

CAUA:

113043782 113067236

CGIB:

127947153 128013752

PTET:

122331229(tmed6)

LROH:

127156317(tmed6)

OMC:	131534156(tmed6)

PPRM:

120468077 120481144(tmed6)

RKG:	130083296(tmed6)

MAMB:

125247540(tmed6)

CIDE:

127506792 127506793 127507694 127507749

CERY:

137014827 137015178(tmed6)

MASI:

127436313

TROS:

130552001(tmed6)

TDW:	130414275(tmed6)

MANU:

129433972(tmed6)

PDAB:

135780931 135787994

IPU:	108269147 108269330

IFU:	128611704 128611804

PHYP:

113528813 113529292

SMEO:

124386236 124386328

TFD:	113636184 113636185

TVC:	132855872 132855969

CGAR:

128531812 128531813

NGRA:

132890224 132890225

TRN:	134318724 134319034

AMEX:

103024064(tmed6) 111195796

CMAO:

118806809 118806812

EEE:	113585287 113585322

CHAR:

105900731 105900732

SPIL:

134094091 134094736

TRU:	101075014(tmed6)

TFS:	130536230(tmed6)

TNG:	GSTEN00019713G001

LCO:	104927016 109142065 109143165

TBEN:

117479800 117479810

CGOB:

115009234 115009236

PGEO:

117447578 117447579 117448544

GACU:

117541373

EMAC:

134881036 134883843

ELY:	117261592 117262647

EFO:	125887781(tmed6) 125887784

PLEP:

121964932 121964933

SLUC:

116036355(tmed6) 116036356

ECRA:

117949755 117949757

ESP:	116693769 116693789

PFLV:

114559628 114560113

GAT:	120809332(tmed6) 120809333

PPUG:

119196698 119196699

AFB:	129108836 129108854

CLUM:

117732609 117732692

PSWI:

130194924(tmed6) 130195119

CANA:

137799590 137799593 137804076(tmed6)

CVE:	137881421 137881672(tmed6)

MSAM:

119893924 119894007

SCHU:

122874902 122874925

CUD:	121515408(tmed6)

SPUL:

138612618(tmed6)

LMIX:

132973559(tmed6)

ALAT:

119024631 119024878(tmed6)

ASTR:

137593893(tmed6)

MZE:	101465737(tmed6)

ONL:

100702597

OAU:	116334533(tmed6)

OLA:	101160497(tmed6)

OML:	112163187(tmed6)

CSAI:

133444803(tmed6)

XMA:	102222126(tmed6)

XCO:	114160095(tmed6)

XHE:	116709111(tmed6)

PRET:

103470749(tmed6)

PFOR:

103137591(tmed6)

PLAI:

106942815(tmed6)

PMEI:

106910767(tmed6)

GAF:	122835207(tmed6)

PPRL:

129376848(tmed6)

CVG:	107099720(tmed6)

CTUL:

119776072(tmed6)

GMU:	124879607(tmed6)

NFU:	107396687(tmed6)

KMR:	108249509(tmed6)

ALIM:

106527561(tmed6)

AOCE:

111564072(tmed6)

EJA:	138206399(tmed6)

BFRE:

138633425(tmed6)

MCEP:

125014650 125014905

CSEM:

103379905(tmed6)

POV:	109624096 109624295

SSEN:

122776425(tmed6)

SSOE:

131470354(tmed6)

HHIP:

117762797(tmed6) 117762801

HSP:	118109889(tmed6)

PPLT:

128444844(tmed6) 128445000

SMAU:

118315375 118315400

LCF:	108872663 108872676(tmed6)

SDU:	111235985 111235986

SLAL:

111651041 111665395(tmed6)

XGL:	120793387 120793394

HCQ:	109507920(tmed6)

SSCV:

137839520(tmed6)

SBIA:

133511761(tmed6)

PTAO:

133478222(tmed6)

BPEC:

110166784(tmed6)

ENY:	140349023(tmed6)

MALB:

109952784 109952785

BSPL:

114857102(tmed6) 114857354 114857355

SJO:	128358996 128359173

SSCO:

133977142 133977143

GMH:	115551000 115551510

SASA:

106561071 106561072

STRU:

115197073 115197074

OTW:	112218254 112218255

OMY:	110492368 110492381

OGO:	124039417 124039424(tmed6)

ONE:	115134498 115134499

OKI:	109867648 109867822

OKE:	118396434 118396436(tmed6)

OMM:	135508860 135509595

OCLA:

139381435 139381443

SALP:

111962136 111962137

SNH:	120066110 120066111

CCLU:

121531202 121531383

ELS:	105018645 105018656

OEP:	134021747 134021748

SFM:	108926288 108926293

PKI:	111843564 111843569(tmed6)

AANG:

118215051 118228269

AROT:

135241547 135255527

CCOG:

133111450 133131734

LOC:	102688074(tmed6)

PSPA:

121296503 121326277

ARUT:

117425081(tmed6)

PSEX:

120535518(tmed6)

LCM:	102357292(TMED6) 106705352

CMK:	103175971(tmed6)

RTP:	109938037(tmed6)

CPLA:

122558719(tmed6)

HOC:	132824061(tmed6)

LERI:

129705413(tmed6)

LRJ:	133344459(TMED6)

BFO:	118407982 118407983 118423749 118423754 118424438 118424535 118424840

BBEL:

109477977 109478147 109478721 109478722 109478723 109478725 109478734

CIN:	100175125 100176919

SCLV:

120329083 120329084 120330912

SPU:

100888120

LPIC:

129276319

AJJ:	139975952 139976277

APLC:

ARUN:

AAMU:

AFIL:

SKO:	100366413 100373288 102804906

PFLL:

139137550

DME:	Dmel_CG10733(loj)

DER:

6545283

DSI:	Dsimw501_GD13935(Dsim_GD13935)

DYA:	Dyak_GE21539

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI12612

DAZ:

DNV:

DHE:

CCAT:

BOD:

BDR:

RZE:

AOQ:	129240917 129242766

ALUD:

128862286

TDA:

119668582

MDE:	101887571 131801302

SCAC:

106092911

LCQ:

111690712

LSQ:

119601945

CVJ:	135953383(loj)

GFS:

ECOE:

CLON:

HIS:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ000287

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

TLN:

HST:

DQU:

CFO:

FEX:	115243283 115243284

PMEC:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

138125546(loj)

DPA:

109545420

ESIM:

136413511(loj)

EFOR:

136342569(loj)

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_212440

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137930488(loj)

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

CSTB:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106678406(loj)

NLU:

111048715

HVI:	124366210 124366214

MQU:	129002372 129002496

PHU:	Phum_PHUM045400

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138696418(loj)

SGRE:

126353940

BROR:

134538884

IEL:

124159073

HAMR:

139691844(loj)

FCD:

110856904

DPX:	DAPPUDRAFT_45190

DMK:

116931365

AFRA:

136041479

PVM:	113816890(loj)

PJA:

PCHN:

PMOO:

HAME:

PCLA:

123762991(loj)

PTRU:

123517484

MNZ:

135195531

MRJ:	136852014(loj)

PORN:

139763517(loj)

HAZT:

108680519

EAF:

111695116

LSM:	121115935(loj)

TCF:

131879807

PPOI:

119109727 119110202 119110602

ISC:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

CVS:	136982147(loj)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

HRO:	HELRODRAFT_77167

LGI:	LOTGIDRAFT_142774

PCAN:

112558124

BGT:

106064585

GAE:	121389953 121390364

HRF:	124137879 124137880 124144976

HRJ:	124265919 124277653 124277654

HASI:

137255609 137255615 137268349

HCRA:

139477391 139477431 139477764

CRG:	105343118 105346999 105348837

CANU:

128187185 128188143 128188923

CVN:	111134617 111135469 111135919 111137340

OED:	125664801 125675660 125677571

MYI:

PMAX:

AIRR:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

LLON:

Reference

PMID:22129529

Authors

Wang X, Yang R, Jadhao SB, Yu D, Hu H, Glynn-Cunningham N, Sztalryd C, Silver KD, Gong DW

Title

Transmembrane emp24 protein transport domain 6 is selectively expressed in pancreatic islets and implicated in insulin secretion and diabetes.

Journal

Pancreas 41:10-4 (2012)
DOI:10.1097/MPA.0b013e318223c7e4

Sequence

[mmu:66269]

LinkDB

DBGET integrated database retrieval system