KEGG   ORTHOLOGY: K20501
Entry
K20501            Tight     KO                                     
Symbol
THCAS
Name
tetrahydrocannabinolic acid synthase [EC:1.21.3.7]
Pathway
map00999  Biosynthesis of various plant secondary metabolites
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00894  Cannabidiol biosynthesis, malonyl-CoA => cannabidiol/dronabinol
Reaction
R12101  cannabigerolate:oxygen oxidoreductase (cyclizing, Delta9-tetrahydrocannabinolate-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00999 Biosynthesis of various plant secondary metabolites
    K20501  THCAS; tetrahydrocannabinolic acid synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.21  Catalysing the reaction X-H + Y-H = X-Y
   1.21.3  With oxygen as acceptor
    1.21.3.7  tetrahydrocannabinolic acid synthase
     K20501  THCAS; tetrahydrocannabinolic acid synthase
Genes
CSAV: 115696884 115697880
AG: BAC41356(THCAS)
Reference
PMID:15190053
  Authors
Sirikantaramas S, Morimoto S, Shoyama Y, Ishikawa Y, Wada Y, Shoyama Y, Taura F
  Title
The gene controlling marijuana psychoactivity: molecular cloning and heterologous expression of Delta1-tetrahydrocannabinolic acid synthase from Cannabis sativa L.
  Journal
J Biol Chem 279:39767-74 (2004)
DOI:10.1074/jbc.M403693200
  Sequence
[ag:BAC41356]
LinkDB

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