KEGG   ORTHOLOGY: K20512
Entry
K20512            Tight     KO                                     
Symbol
CYP725A3
Name
taxoid 14beta-hydroxylase [EC:1.14.13.146]
Pathway
map00904  Diterpenoid biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R09867  10beta-hydroxytaxa-4(20),11-dien-5alpha-yl-acetate,NADPH:oxygen 14-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00904 Diterpenoid biosynthesis
    K20512  CYP725A3; taxoid 14beta-hydroxylase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K20512  CYP725A3; taxoid 14beta-hydroxylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.146  taxoid 14beta-hydroxylase
     K20512  CYP725A3; taxoid 14beta-hydroxylase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP725 family
   K20512  CYP725A3; taxoid 14beta-hydroxylase
Other DBs
GO: 0036203
Genes
AG: AAO66199
Reference
PMID:12729625
  Authors
Jennewein S, Rithner CD, Williams RM, Croteau R
  Title
Taxoid metabolism: Taxoid 14beta-hydroxylase is a cytochrome P450-dependent monooxygenase.
  Journal
Arch Biochem Biophys 413:262-70 (2003)
DOI:10.1016/S0003-9861(03)00090-0
  Sequence
[ag:AAO66199]
Reference
PMID:24413977
  Authors
Zhao YJ, Cheng QQ, Su P, Chen X, Wang XJ, Gao W, Huang LQ
  Title
Research progress relating to the role of cytochrome P450 in the biosynthesis of terpenoids in medicinal plants.
  Journal
Appl Microbiol Biotechnol 98:2371-83 (2014)
DOI:10.1007/s00253-013-5496-3
LinkDB

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