KEGG   ORTHOLOGY: K20545
Entry
K20545            Tight     KO                                     
Symbol
CYP716A47, PPDS
Name
dammarenediol 12-hydroxylase [EC:1.14.14.120]
Pathway
map00999  Biosynthesis of various plant secondary metabolites
map01110  Biosynthesis of secondary metabolites
Reaction
R10540  dammarenediol-II,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12beta-hydroxylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00999 Biosynthesis of various plant secondary metabolites
    K20545  CYP716A47, PPDS; dammarenediol 12-hydroxylase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K20545  CYP716A47, PPDS; dammarenediol 12-hydroxylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.120  dammarenediol 12-hydroxylase
     K20545  CYP716A47, PPDS; dammarenediol 12-hydroxylase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP716 family
   K20545  CYP716A47, PPDS; dammarenediol 12-hydroxylase
Genes
AG: AEY75212(PPDS)
Reference
PMID:22039120
  Authors
Han JY, Kim HJ, Kwon YS, Choi YE
  Title
The Cyt P450 enzyme CYP716A47 catalyzes the formation of protopanaxadiol from dammarenediol-II during ginsenoside biosynthesis in Panax ginseng.
  Journal
Plant Cell Physiol 52:2062-73 (2011)
DOI:10.1093/pcp/pcr150
  Sequence
[ag:AEY75212]
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