KEGG   ORTHOLOGY: K20546
Entry
K20546            Tight     KO                                     
Symbol
CYP716A53
Name
protopanaxadiol 6-hydroxylase [EC:1.14.14.121]
Pathway
map00999  Biosynthesis of various plant secondary metabolites
map01110  Biosynthesis of secondary metabolites
Reaction
R10591  protopanaxadiol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00999 Biosynthesis of various plant secondary metabolites
    K20546  CYP716A53; protopanaxadiol 6-hydroxylase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K20546  CYP716A53; protopanaxadiol 6-hydroxylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.121  protopanaxadiol 6-hydroxylase
     K20546  CYP716A53; protopanaxadiol 6-hydroxylase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP716 family
   K20546  CYP716A53; protopanaxadiol 6-hydroxylase
Genes
AG: AFO63031
Reference
PMID:22875608
  Authors
Han JY, Hwang HS, Choi SW, Kim HJ, Choi YE
  Title
Cytochrome P450 CYP716A53v2 catalyzes the formation of protopanaxatriol from protopanaxadiol during ginsenoside biosynthesis in Panax ginseng.
  Journal
Plant Cell Physiol 53:1535-45 (2012)
DOI:10.1093/pcp/pcs106
  Sequence
[ag:AFO63031]
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