| Entry |
|
| Symbol |
livN, parN
|
| Name |
5'''-epimerase [EC:5.1.3.-]
|
| Pathway |
| map00524 | Neomycin, kanamycin and gentamicin biosynthesis |
| map01110 | Biosynthesis of secondary metabolites |
|
| Reaction |
| R11286 | paromomycin-II 5'''-epimerase |
| R11288 | 5'''-epi-lividomycin-B 5'''-epimerase |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
K20588 livN, parN; 5'''-epimerase
|
| Other DBs |
|
| Genes |
|
| Reference |
|
| Authors |
Clausnitzer D, Piepersberg W, Wehmeier UF |
| Title |
The oxidoreductases LivQ and NeoQ are responsible for the different 6'-modifications in the aminoglycosides lividomycin and neomycin. |
| Journal |
|
| Reference |
|
| Authors |
Arya DP (ed). |
| Title |
Aminoglycoside antibiotics: From chemical biology to drug discovery |
| Journal |
Wiley-Interscience (2007) |
| LinkDB |
|