KEGG   ORTHOLOGY: K20981
Entry
K20981            Tight     KO                                     
Symbol
LOVB
Name
lovastatin nonaketide synthase [EC:2.3.1.161]
Pathway
map00997  Biosynthesis of various other secondary metabolites
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00893  Lovastatin biosynthesis, malonyl-CoA => lovastatin acid
Reaction
R07251  acyl-CoA:malonyl-CoA C-acyltransferase (dihydromonacolin L-[acp]-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00997 Biosynthesis of various other secondary metabolites
    K20981  LOVB; lovastatin nonaketide synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.161  lovastatin nonaketide synthase
     K20981  LOVB; lovastatin nonaketide synthase
Other DBs
GO: 0050637
Genes
AG: AAD39830(LOVB)
Reference
  Authors
Ma SM, Li JW, Choi JW, Zhou H, Lee KK, Moorthie VA, Xie X, Kealey JT, Da Silva NA, Vederas JC, Tang Y
  Title
Complete reconstitution of a highly reducing iterative polyketide synthase.
  Journal
Science 326:589-92 (2009)
DOI:10.1126/science.1175602
  Sequence
LinkDB

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