ORTHOLOGY: K20981
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Entry
K20981 Tight KO
Symbol
LOVB
Name
lovastatin nonaketide synthase [EC:
2.3.1.161
]
Pathway
map00997
Biosynthesis of various other secondary metabolites
map01100
Metabolic pathways
map01110
Biosynthesis of secondary metabolites
Module
M00893
Lovastatin biosynthesis, malonyl-CoA => lovastatin acid
Reaction
R07251
acyl-CoA:malonyl-CoA C-acyltransferase (dihydromonacolin L-[acp]-forming)
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09100 Metabolism
09110 Biosynthesis of other secondary metabolites
00997 Biosynthesis of various other secondary metabolites
K20981 LOVB; lovastatin nonaketide synthase
Enzymes [BR:
ko01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.161 lovastatin nonaketide synthase
K20981 LOVB; lovastatin nonaketide synthase
BRITE hierarchy
Other DBs
GO:
0050637
Genes
AG:
AAD39830
(LOVB)
Taxonomy
UniProt
Reference
PMID:
19900898
Authors
Ma SM, Li JW, Choi JW, Zhou H, Lee KK, Moorthie VA, Xie X, Kealey JT, Da Silva NA, Vederas JC, Tang Y
Title
Complete reconstitution of a highly reducing iterative polyketide synthase.
Journal
Science 326:589-92 (2009)
DOI:
10.1126/science.1175602
Sequence
[ag:
AAD39830
]
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