| Entry |
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| Symbol |
LOVF
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| Name |
2-methylbutanoate polyketide synthase [EC: 2.3.1.244]
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| Pathway |
| map00997 | Biosynthesis of various other secondary metabolites |
| map01110 | Biosynthesis of secondary metabolites |
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| Module |
| M00893 | Lovastatin biosynthesis, malonyl-CoA => lovastatin acid |
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| Reaction |
| R11445 | malonyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, methylating, 2-methylbutanoate-forming) |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09110 Biosynthesis of other secondary metabolites
00997 Biosynthesis of various other secondary metabolites
K20984 LOVF; 2-methylbutanoate polyketide synthase
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins
K20984 LOVF; 2-methylbutanoate polyketide synthase
Enzymes [BR:ko01000]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.244 2-methylbutanoate polyketide synthase
K20984 LOVF; 2-methylbutanoate polyketide synthase
Polyketide biosynthesis proteins [BR:ko01008]
Polyketide synthase (PKS)
Iterative type I PKS
Fungal nonreducing PKS (NR-PKS)
K20984 LOVF; 2-methylbutanoate polyketide synthase
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| Genes |
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| Reference |
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| Authors |
Kennedy J, Auclair K, Kendrew SG, Park C, Vederas JC, Hutchinson CR |
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| Title |
Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis. |
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| Journal |
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| Sequence |
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| LinkDB |
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