KEGG   ORTHOLOGY: K21046
Entry
K21046            Tight     KO                                     

Name
UL146
Definition
HCMV chemokine vCXCL1
Pathway
ko04061  Viral protein interaction with cytokine and cytokine receptor
ko05163  Human cytomegalovirus infection
Network
nt06124  Chemokine signaling (viruses)
nt06150  Cytokine-cytokine receptor interaction (viruses)
nt06167  Human cytomegalovirus (HCMV)
  Element
N00427  HCMV vCXCL to CXCR-GNB/G-PI3K-AKT signaling pathway
N01237  HCMV vCXCL1 to CXCR1 signaling
N01264  HCMV vCXCL1 to CX3CR1 signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04061 Viral protein interaction with cytokine and cytokine receptor
    K21046  UL146; HCMV chemokine vCXCL1
 09160 Human Diseases
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    K21046  UL146; HCMV chemokine vCXCL1
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K21046  UL146; HCMV chemokine vCXCL1
Viral proteins [BR:ko03200]
 dsDNA viruses
  Human cytomegalovirus (Human herpesvirus 5)
   K21046  UL146; HCMV chemokine vCXCL1
Genes
VG: 3077566(UL146)
Reference
  Authors
Penfold ME, Dairaghi DJ, Duke GM, Saederup N, Mocarski ES, Kemble GW, Schall TJ
  Title
Cytomegalovirus encodes a potent alpha chemokine.
  Journal
Proc Natl Acad Sci U S A 96:9839-44 (1999)
DOI:10.1073/pnas.96.17.9839
  Sequence
[vg:3077566]
Reference
  Authors
Luttichau HR
  Title
The cytomegalovirus UL146 gene product vCXCL1 targets both CXCR1 and CXCR2 as an agonist.
  Journal
J Biol Chem 285:9137-46 (2010)
DOI:10.1074/jbc.M109.002774
  Sequence
[vg:3077566]
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