KEGG   ORTHOLOGY: K21173
Entry
K21173                      KO                                     
Symbol
calE6
Name
methionine gamma-lyase
Pathway
map01059  Biosynthesis of enediyne antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00825  10-membered enediyne core biosynthesis, malonyl-CoA => 3-hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-ACP => 10-membered enediyne core
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01059 Biosynthesis of enediyne antibiotics
    K21173  calE6; methionine gamma-lyase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K21173  calE6; methionine gamma-lyase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Others
   K21173  calE6; methionine gamma-lyase
Other DBs
COG: COG0626
Genes
NBR: O3I_023140
NOZ: DMB37_04420
NAH: F5544_22930
NVU: V7968_30920
SBRO: GQF42_15220
SAKB: K1J60_26375
SXT: KPP03845_102886(metC)
ACTW: F7P10_19345
ACIR: OG979_40420
SPIQ: OHA34_04140
AMYC: CU254_17400
SAQ: Sare_2181
MICB: MicB006_4953
MCRA: ID554_11805
MCHL: PVK74_00410
PSUU: Psuf_058470(metB)
PRY: Prubr_36610(metB)
AG: AAM94792(calE6)
 » show all
Reference
PMID:12183629
  Authors
Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS
  Title
The calicheamicin gene cluster and its iterative type I enediyne PKS.
  Journal
Science 297:1173-6 (2002)
DOI:10.1126/science.1072105
  Sequence
[ag:AAM94792]
Reference
PMID:25404066
  Authors
Song H, Xu R, Guo Z
  Title
Identification and characterization of a methionine gamma-lyase in the calicheamicin biosynthetic cluster of Micromonospora echinospora.
  Journal
Chembiochem 16:100-9 (2015)
DOI:10.1002/cbic.201402489
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