KEGG ORTHOLOGY: K21214

ORTHOLOGY: K21214

Entry

K21214                      KO

Symbol

ncsC4

Name

NDP-hexose 4-ketoreductase

Pathway

map01059

Biosynthesis of enediyne antibiotics

map01110

Biosynthesis of secondary metabolites

Reaction

R11433

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01059 Biosynthesis of enediyne antibiotics
    K21214  ncsC4; NDP-hexose 4-ketoreductase

Other DBs

COG:

COG0451

Genes

RID:	RIdsm_03014(galE_2)

ROH:	FIU89_10510(galE1)

PSEB:

EOK75_07540

PALW:

PSAL_026050

PSHQ:

F3W81_14575

RCP:	RCAP_rcc03225

RHP:	LPB142_14530

PLH:	VT85_20550(rmd_2)

IPA:

Isop_3611

SACI:

Sinac_3094

PBOR:

BSF38_04700(rmd_4)

AGV:	OJF2_59130(rmd_3)

TPLA:

ElP_38840(rmd_3)

SACV:

SPACI_042620(rmd_2)

NBR:	O3I_015220 O3I_015240

NTP:	CRH09_07950

NIE:	KV110_14260 KV110_14280

NVU:	V7968_22980 V7968_23000

SCO:

SCO5176

SALB:

XNR_1627

SMA:	SAVERM_1014 SAVERM_3084 SAVERM_359

SGR:

SGR_2349

SGB:

WQO_23755

SFI:

SFUL_4986

SANL:

KZO11_25185 KZO11_29605

SGRF:

SGFS_013900 SGFS_016230 SGFS_044360

SCYE:

R2B67_10780 R2B67_24680 R2B67_24820

SCB:	SCAB_30871

SSX:	SACTE_4406 SACTE_5594

SVL:	Strvi_1494 Strvi_3807

SHY:

SHJG_6282

SHO:	SHJGH_6043

SRC:	M271_00370 M271_06430 M271_18035

SMAL:

SMALA_5129 SMALA_7126

SAUO:

BV401_29460 BV401_39260

SSOI:

I1A49_29330 I1A49_39410

SANT:

QR300_05450 QR300_16015

SFA:

Sfla_2115

SBH:	SBI_04053 SBI_06868 SBI_06870 SBI_08411(nanG4)

SVE:

SVEN_4826

SDV:	BN159_0781 BN159_3229

SALS:

SLNWT_0675 SLNWT_0805 SLNWT_2131 SLNWT_7315

STRP:

F750_4701

SCI:	B446_13380 B446_13480 B446_24375

SLV:	SLIV_12500

SGU:	SGLAU_01475 SGLAU_22205

SVT:	SVTN_25065

STRE:

GZL_03529

SCW:	TU94_03150 TU94_21510

SLD:	T261_2875 T261_6849 T261_6860 T261_6861

SLC:	SL103_12600 SL103_29955

SXI:	SXIM_37530

STRM:

M444_22660 M444_29345

STRC:

AA958_23410

SAMB:

SAM23877_4959 SAM23877_6984

SPRI:

SPRI_0241 SPRI_2700 SPRI_7112

SCZ:	ABE83_11595

SCX:	AS200_17965

SRW:	TUE45_00734(tal_1) TUE45_05672(tal_3)

STRF:

ASR50_23530

SLE:	sle_25660(sle_25660) sle_62550(sle_62550)

SRN:	A4G23_03788(tal_2)

SPAV:

Spa2297_21845

STRT:

A8713_20845 A8713_30200

SCLF:

BB341_08560

SGS:	AVL59_06620 AVL59_46075 AVL59_46155

STSI:

A4E84_26545 A4E84_39000

SKY:	D0C37_09875

SALW:

CP975_00180 CP975_23520 CP975_28030

SGM:	GCM10017557_27250 GCM10017557_73650 GCM10017557_73980

SCAD:

DN051_14525

SPHW:

NFX46_05870 NFX46_12270

SGRS:

V9K83_10890

SLS:	SLINC_5561

SNR:	SNOUR_15590

SALU:

DC74_5325 DC74_6603 DC74_6615

SALL:

SAZ_28230 SAZ_34330 SAZ_34390

SPLU:

LK06_022090 LK06_031060

STRD:

NI25_13295

SNW:	BBN63_10865 BBN63_25005 BBN63_25015

SSIA:

A7J05_08860 A7J05_12850

SVU:	B1H20_24260

SPUN:

BFF78_11225 BFF78_15090

SGV:	B1H19_26750

SLAU:

SLA_5004

SALF:

SMD44_05743

SALJ:

SMD11_2378 SMD11_5925

SLX:	SLAV_13735(tal1) SLAV_35705(tal3)

STRO:

STRMOE7_07490 STRMOE7_25430

SFK:

KY5_5288

SNZ:	DC008_02040 DC008_22955

SGE:	DWG14_02971(tal_2)

SRJ:	SRO_2636 SRO_6824

SVQ:	N6Q81_23120 N6Q81_32435

SLK:	SLUN_26235 SLUN_34800

SDX:	C4B68_09665 C4B68_09675 C4B68_13700

SGD:	ELQ87_00885 ELQ87_05695 ELQ87_08075 ELQ87_13535

SQZ:	FQU76_22975

SCYA:

EJ357_30545

SAST:

CD934_11025 CD934_33075

SNQ:	CP978_22220 CP978_29675 CP978_29685

STIR:

DDW44_01145 DDW44_20155 DDW44_27810

SKA:	CP970_14725 CP970_39900

SGZ:	C0216_04780

SVN:	CP980_11765

SNK:	CP967_11145

SHAW:

CEB94_27085 CEB94_39305

SRK:	FGW37_03400 FGW37_21610

SFIC:

EIZ62_02340 EIZ62_10935

SGAL:

CP966_24040 CP966_29040

SSPO:

DDQ41_09645 DDQ41_22850

SVR:	CP971_12665 CP971_17205

SPAD:

DVK44_23435

SFY:	GFH48_15190

SAQU:

EJC51_31875

SGF:	HEP81_02847 HEP81_07163

SCAV:

CVT27_23005

SSEO:

D0Z67_19290

SBY:	H7H31_10535 H7H31_32290

SRIM:

CP984_13550

SSUB:

CP968_11950

SPHV:

F9278_03140 F9278_32960

SCIN:

CP977_22800 CP977_28085 CP977_29070

SFUG:

CNQ36_23445

SPAC:

B1H29_02095 B1H29_12690

STSU:

B7R87_21960 B7R87_22000 B7R87_22720

SCHA:

CP983_14850 CP983_41995

SGX:	H4W23_26600

SCOE:

CP976_28390 CP976_32985

SBAT:

G4Z16_10205

SSPB:

CP982_27460 CP982_31720

SNF:	JYK04_05532(tal_2)

SPLA:

CP981_25700

SBRO:

GQF42_05200 GQF42_28450

STUI:

GCM10017668_46990 GCM10017668_68090

SATA:

C5746_27410

SCHF:

IPT68_23815 IPT68_29245 IPT68_29255

SHUN:

DWB77_01258(tal_1) DWB77_02734(tal_2) DWB77_05141(tal_3) DWB77_05161(galE_7)

SHAR:

HUT13_18570 HUT13_24955

SCYG:

S1361_04980(tal1) S1361_25635(tal3) S1361_29915(rmd) S1361_29980(tal4)

SFEU:

IM697_37660 IM697_37980

SLIA:

HA039_05660 HA039_05780 HA039_11150

SDW:	K7C20_24455 K7C20_32600

SVD:	CP969_04520 CP969_25295

SCAL:

I6J39_24010 I6J39_34730

SAUH:

SU9_023185 SU9_032925 SU9_033045

SFB:	CP974_20530

SMOB:

J7W19_02895 J7W19_17595 J7W19_21335

SPRA:

CP972_23620 CP972_29255

SPEU:

CGZ69_24385

SROI:

IAG44_13445

SXN:	IAG42_11905 IAG42_35890

SGJ:	IAG43_21165

SHK:	J2N69_24515 J2N69_28820 J2N69_29320

SANU:

K7396_04495 K7396_12395 K7396_33560 K7396_33605

SDD:	D9753_12190 D9753_33715

SACT:

DMT42_25730

SMAO:

CAG99_07570

SGOB:

test1122_18430

SINE:

KI385_25285 KI385_29600

SLF:	JEQ17_16760

SDEC:

L3078_04685 L3078_30345

SAOV:

G3H79_07760 G3H79_11995

SDUR:

M4V62_06350 M4V62_15755

SYAN:

NRK68_22490

SRUG:

F0345_19955

SAKB:

K1J60_14950 K1J60_41445

STAA:

LDH80_09640 LDH80_14365

SNIG:

HEK616_47310 HEK616_58810

SVIO:

HWN34_08820

SCAE:

IHE65_14470 IHE65_41630

STUB:

MMF93_21910 MMF93_33215

SSPN:

LXH13_14090 LXH13_26315

SCIR:

STRCI_005360 STRCI_007640

SXT:	KPP03845_104939(tal_3)

SLON:

LGI35_28605 LGI35_31695

SDRZ:

NEH16_10545

STUD:

STRTU_002340 STRTU_005086 STRTU_006755

STEE:

F3L20_05395

SGK:	PET44_21390 PET44_27860

SYUN:

MOV08_15430

SARG:

HKX69_11800

SJN:	RI060_04570 RI060_13875 RI060_18310

SCYN:

N8I84_26105

SOV:	QZH56_10815 QZH56_32440

SFIY:

F0344_11165

SHAU:

K9S39_16540 K9S39_40600

SKG:	KJK29_11725 KJK29_16110

SCOA:

QU709_13675

SLAI:

P8A22_08915 P8A22_08985 P8A22_12985

SROC:

RGF97_10390

SFP:	QUY26_12805

SCHG:

NRO40_19770

STTN:

BSL84_22055

SINN:

ABB07_13275

STRZ:

OYE22_10160 OYE22_32280

SCAY:

PYS65_06650 PYS65_12195

KBU:	Q4V64_34665

SARM:

DVA86_01045 DVA86_01725

SPRF:

K4G22_08960

SLUO:

PS467_26950

STPB:

QR97_21740 QR97_36115

SRPA:

HEP86_26725

SMIB:

SMIR_11885

SCAJ:

O1G22_14760

STRW:

QHG49_02705 QHG49_12720

STRL:

HEP84_02945 HEP84_33270

STSD:

HEP87_34410

SRPZ:

HEP85_00615 HEP85_26365 HEP85_42160

SCHE:

QRN89_03205 QRN89_14780 QRN89_22785

SGLY:

P8A20_12265

SCAT:

P8A18_23115 P8A18_33650

STII:

DRB96_29305

STIC:

DRB89_07955

SABD:

N8I86_03655 N8I86_24920

STRV:

SPAZ:

SPIH:

SMOD:

SPOF:

STBR:

SGRO:

STAC:

ABII15_25335 ABII15_31655 ABII15_31665

STVB:

OH133_10825 OH133_12455 OH133_33490

SSOC:

ABZO31_22195 ABZO31_28340

SSLI:

R2D22_12665

STYI:

C9F11_26735(tal2) C9F11_30690(tal3)

SCIT:

V2W30_26045

SSIR:

WAB15_27055

STRJ:

H7827_09190

SEXP:

SLV14_000461 SLV14_000473 SLV14_002651

SFLU:

ACKTSN_16540

SOKE:

ACE1N8_23300

SSTO:

ACE1OC_14300

SLUA:

AB8735_06360 AB8735_24445

STGO:

KBP30_15345

STCM:

SCMC78_21670

STID:

G7Z12_01795 G7Z12_12285

STCZ:

JHY03_48070

STSG:

B6R96_12695

STHU:

M1P56_11700 M1P56_28695

STRQ:

CGL27_30620

SSEC:

ABZO29_16540

SHUG:

ABVG11_04380 ABVG11_13420

STRK:

R2B38_27840

STJL:

ACE1OA_12195

STPG:

C1703_26015(tal3)

STPJ:

R1Y80_25075

SCT:	SCAT_4035 SCAT_5772

SCY:	SCATT_40210 SCATT_57750

KSK:

KSE_48810

KAB:	B7C62_24695 B7C62_31120

KAU:	B6264_07720 B6264_12210

KIT:	CFP65_4839

KIS:	HUT16_22410 HUT16_23810

KCH:	O1G21_15710 O1G21_20535

KCM:	ABWK59_21380

KNB:	ACF9IK_13625 ACF9IK_18605

KIC:	KCMC57_up25370

KPUR:

ACFCLZ_15845 ACFCLZ_18460

STRI:

C7M71_011570 C7M71_019870 C7M71_025895

PPOD:

AB0761_15120

STRH:

GXP74_05430

ABRY:

NYE86_15430 NYE86_29250

AGLA:

OIE69_15750

AREV:

RVR_2934 RVR_6769

XYL:	ET495_09205

IHA:	UQW22_05195

ARUB:

J5A65_00465

KFL:

Kfla_0021

KQI:	F1D05_20705

KSL:	OG809_11760

KRI:	OX958_01450

TALX:

FOF52_07405 FOF52_07495 FOF52_14820

NAL:

B005_1453

NGV:	CDO52_02800

NCG:	KGD84_13450

TCU:	Tcur_2762 Tcur_2789

AGRA:

AGRA3207_007110 AGRA3207_007757

AMAZ:

LUW76_46790

AMYZ:

HUW46_07979(tal_2)

AMYS:

CVV72_32545

SESP:

BN6_29610

SSYI:

EKG83_13440 EKG83_24950

KAL:

KALB_2069

KUT:	JJ691_64770

KBR:	Q4V65_19090

KPHY:

AOZ06_07200 AOZ06_22545 AOZ06_32075

ACTI:

UA75_16835

AHG:	AHOG_15440

PMAD:

BAY61_07760 BAY61_07785

ACTU:

Actkin_02429(perS11)

CROS:

N8J89_11200 N8J89_20270

MAU:	Micau_2118 Micau_4006 Micau_4016

MIL:	ML5_2221 ML5_4405 ML5_4415

MICB:

MicB006_4927 MicB006_5179

MTUA:

CSH63_14200

MICH:

FJK98_07160 FJK98_09985

MCAB:

HXZ27_03950(evdS1) HXZ27_11045

MCRA:

ID554_02990 ID554_11940

VER:	HUT12_10150

MENO:

MCHL:

MFEU:

MPRN:

MHAW:

MCAY:

PVK37_16345 PVK37_23820 PVK37_26175

MICF:

QQG74_13780

VET:	ACQVFL_09450

ASE:

ACTN:

ACTS:

ACTL:

PRY:	Prubr_68770

DVC:	Dvina_17980

DMAT:

Dmats_26265

DROS:

Drose_26775

DACT:

KZZ52_34300

CCAZ:

COUCH_15970 COUCH_16025

DCH:	SY84_03960

DPU:	SU48_07670

DWU:	DVJ83_07770

DFC:

DFI_16320

DEIN:

DAAJ005_15225

DGA:	DEGR_21190

DSC:	ABOD76_00205

AG:	AAM77980(ncsC4)

» show all

Reference

PMID:15797213

Authors

Liu W, Nonaka K, Nie L, Zhang J, Christenson SD, Bae J, Van Lanen SG, Zazopoulos E, Farnet CM, Yang CF, Shen B

Title

The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases.

Journal

Chem Biol 12:293-302 (2005)
DOI:10.1016/j.chembiol.2004.12.013

Sequence

[ag:AAM77980]

LinkDB

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