ORTHOLOGY: K21254
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Entry
K21254 KO
Symbol
calO5
Name
orsellinic acid synthase [EC:2.3.1.-]
Pathway
map01059
Biosynthesis of enediyne antibiotics
map01100
Metabolic pathways
map01110
Biosynthesis of secondary metabolites
Module
M00833
Calicheamicin biosynthesis, calicheamicinone => calicheamicin
M00834
Calicheamicin orsellinate moiety biosynthesis, malonyl-CoA => orsellinate-ACP => 5-iodo-2,3-dimethoxyorsellinate-ACP
Reaction
R11412
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01059 Biosynthesis of enediyne antibiotics
K21254 calO5; orsellinic acid synthase
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins
K21254 calO5; orsellinic acid synthase
Polyketide biosynthesis proteins [BR:
ko01008
]
Polyketide synthase (PKS)
Iterative type I PKS
Bacterial type
K21254 calO5; orsellinic acid synthase
BRITE hierarchy
Other DBs
COG:
COG0331
COG3321
Genes
SAQ:
Sare_2029
AG:
AAM70355
(calO5)
Taxonomy
UniProt
Reference
PMID:
12183629
Authors
Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS
Title
The calicheamicin gene cluster and its iterative type I enediyne PKS.
Journal
Science 297:1173-6 (2002)
DOI:
10.1126/science.1072105
Sequence
[ag:
AAM70355
]
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