KEGG   ORTHOLOGY: K21259
Entry
K21259                      KO                                     
Symbol
calG3
Name
calicheamicinone 4-hydroxyamino-4,6-dideoxy-alpha-D-glucosyltransferase [EC:2.4.1.-]
Pathway
map01059  Biosynthesis of enediyne antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00833  Calicheamicin biosynthesis, calicheamicinone => calicheamicin
Reaction
R11417  dTDP-4-hydroxyamino-4,6-dideoxy-alpha-D-glucose:calicheamicinone 4-hydroxyamino-4,6-dideoxy-alpha-D-glucosyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01059 Biosynthesis of enediyne antibiotics
    K21259  calG3; calicheamicinone 4-hydroxyamino-4,6-dideoxy-alpha-D-glucosyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K21259  calG3; calicheamicinone 4-hydroxyamino-4,6-dideoxy-alpha-D-glucosyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Glycosyltransferase
   K21259  calG3; calicheamicinone 4-hydroxyamino-4,6-dideoxy-alpha-D-glucosyltransferase
Other DBs
COG: COG1819
CAZy: GT1
Genes
KBR: Q4V65_35325
SAQ: Sare_2033
AG: AAM94798(calG3)
Reference
  Authors
Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS
  Title
The calicheamicin gene cluster and its iterative type I enediyne PKS.
  Journal
Science 297:1173-6 (2002)
DOI:10.1126/science.1072105
  Sequence
Reference
  Authors
Zhang C, Bitto E, Goff RD, Singh S, Bingman CA, Griffith BR, Albermann C, Phillips GN Jr, Thorson JS
  Title
Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis.
  Journal
Chem Biol 15:842-53 (2008)
DOI:10.1016/j.chembiol.2008.06.011
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