KEGG   ORTHOLOGY: K21294
Entry
K21294                      KO                                     
Symbol
GLIC, ACLC, ROQR
Name
gliotoxin/aspirochlorine/mycotoxins biosynthesis cytochrome P450 monooxygenase [EC:1.-.-.-]
Pathway
map00404  Staurosporine biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R12438  
R12440  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00404 Staurosporine biosynthesis
    K21294  GLIC, ACLC, ROQR; gliotoxin/aspirochlorine/mycotoxins biosynthesis cytochrome P450 monooxygenase
Other DBs
COG: COG2124
Genes
EPA: 110235416
ATEN: 116300856 116306000
ADF: 107341860
AMIL: 114974703 114975373
MCAZ: 138045439 138045440
MFOO: 137975105
PDAM: 113669644
DGT: 114534845
XEN: 124446605
KLA: KLLA0_C19206g
ZMK: HG535_0E00120
MGR: MGG_16917
TMN: UCRPA7_6618
FVR: FVEG_17488
FMU: J7337_009139
TRE: TRIREDRAFT_53168
TRR: M419DRAFT_133450
TATV: 25785799(TrAtP1_011795)
TASP: 36608151(TrAFT101_008349)
MAW: 19252527(J3458_013111)
MAJ: MAA_00972
MBRN: 26244408(tcpC) 26247761(aclC)
PTKZ: JDV02_009520
SAPO: SAPIO_CDS1822
PFY: PFICI_09678
SSL: SS1G_08565
BFU: BCIN_12g04940
AFM: AFUA_3G12960 AFUA_6G09670
ACT: ACLA_066860
NFI: NFIA_055360 NFIA_064360 NFIA_074290
AOR: AO090001000041
ANG: An09g00560
AFV: AFLA_008387
ALUC: AKAW2_40051S
APUU: APUU_20025S APUU_61450A
PCS: N7525_008086
POU: POX_c04518
TMF: EYB26_001586
TRG: TRUGW13939_06182
CIM: CIMG_11806(CIMG06709)
ABE: ARB_03093 ARB_07857
TVE: TRV_01777 TRV_04715 TRV_06059
PNO: SNOG_13040
PTRR: 6342484(PtrM4_090080)
BSC: COCSADRAFT_176614
ZTR: MYCGRDRAFT_36631(CYP-39)
NPA: UCRNP2_9174
SLA: SERLADRAFT_443361 SERLADRAFT_473766 SERLADRAFT_476495(mox2)
 » show all
Reference
PMID:15979823
  Authors
Gardiner DM, Howlett BJ
  Title
Bioinformatic and expression analysis of the putative gliotoxin biosynthetic gene cluster of Aspergillus fumigatus.
  Journal
FEMS Microbiol Lett 248:241-8 (2005)
DOI:10.1016/j.femsle.2005.05.046
  Sequence
[afm:AFUA_6G09670]
Reference
PMID:23434416
  Authors
Chang SL, Chiang YM, Yeh HH, Wu TK, Wang CC
  Title
Reconstitution of the early steps of gliotoxin biosynthesis in Aspergillus nidulans reveals the role of the monooxygenase GliC.
  Journal
Bioorg Med Chem Lett 23:2155-7 (2013)
DOI:10.1016/j.bmcl.2013.01.099
  Sequence
[afm:AFUA_6G09670]
Reference
PMID:25302411
  Authors
Chankhamjon P, Boettger-Schmidt D, Scherlach K, Urbansky B, Lackner G, Kalb D, Dahse HM, Hoffmeister D, Hertweck C
  Title
Biosynthesis of the halogenated mycotoxin aspirochlorine in koji mold involves a cryptic amino acid conversion.
  Journal
Angew Chem Int Ed Engl 53:13409-13 (2014)
DOI:10.1002/anie.201407624
  Sequence
[aor:AO090001000041]
LinkDB

KEGG   REACTION: R12440
Entry
R12440                      Reaction                               
Definition
Roquefortine D <=> Roquefortine C
Equation
C22163 <=> C22165
Comment
cytochrome P450 oxidoreductase
Reaction class
RC03126  C22163_C22165
Enzyme
1.-.-.-
Pathway
rn00404  Staurosporine biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.-  
   1.-.-  
    1.-.-.-
     R12440  Roquefortine D <=> Roquefortine C
Orthology
K21294  gliotoxin/aspirochlorine/mycotoxins biosynthesis cytochrome P450 monooxygenase [EC:1.-.-.-]
LinkDB

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