KEGG   ORTHOLOGY: K21297
Entry
K21297                      KO                                     
Symbol
ctcQ
Name
flavin reductase (NADH) [EC:1.5.1.36]
Pathway
map00253  Tetracycline biosynthesis
map01057  Biosynthesis of type II polyketide products
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00823  Chlortetracycline biosynthesis, pretetramide => chlortetracycline
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K21297  ctcQ; flavin reductase (NADH)
   00253 Tetracycline biosynthesis
    K21297  ctcQ; flavin reductase (NADH)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K21297  ctcQ; flavin reductase (NADH)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.36  flavin reductase (NADH)
     K21297  ctcQ; flavin reductase (NADH)
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Others
   K21297  ctcQ; flavin reductase (NADH)
Other DBs
COG: COG1853
GO: 0036382
Genes
AMYL: QBD29_13685
MMI: MMAR_3634
MMAE: MMARE11_35420
MLI: MULP_03882
MPSE: MPSD_37010
MSHO: MSHO_33260
MMAG: MMAD_31880
NSR: NS506_02368
RKO: JWS14_38875
GJI: H1R19_00440
SHY: SHJG_8629
SDV: BN159_2477(pyr9)
SLD: T261_7912
SRW: TUE45_00621(rbmH_1) TUE45_06418(rbmH_2)
SNF: JYK04_01553(rbmH)
SHUN: DWB77_02860(rbmH)
SEN: SACE_4928
AOI: AORI_5335
AORI: SD37_34215
ASE: ACPL_6145(ntaB)
ACTS: ACWT_6013
AG: AEI98660(ctcQ)
 » show all
Reference
  Authors
Zhu T, Cheng X, Liu Y, Deng Z, You D
  Title
Deciphering and engineering of the final step halogenase for improved chlortetracycline biosynthesis in industrial Streptomyces aureofaciens.
  Journal
Metab Eng 19:69-78 (2013)
DOI:10.1016/j.ymben.2013.06.003
  Sequence
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