KEGG   ORTHOLOGY: K21297
Entry
K21297                      KO                                     
Symbol
ctcQ
Name
flavin reductase (NADH) [EC:1.5.1.36]
Pathway
map00253  Tetracycline biosynthesis
map01057  Biosynthesis of type II polyketide products
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00823  Chlortetracycline biosynthesis, pretetramide => chlortetracycline
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K21297  ctcQ; flavin reductase (NADH)
   00253 Tetracycline biosynthesis
    K21297  ctcQ; flavin reductase (NADH)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K21297  ctcQ; flavin reductase (NADH)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.36  flavin reductase (NADH)
     K21297  ctcQ; flavin reductase (NADH)
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Others
   K21297  ctcQ; flavin reductase (NADH)
Other DBs
COG: COG1853
GO: 0036382
Genes
AMYL: QBD29_13685
MMI: MMAR_3634
MMAE: MMARE11_35420
MLI: MULP_03882
MPSE: MPSD_37010
MSHO: MSHO_33260
MMAG: MMAD_31880
NSR: NS506_02368
RKO: JWS14_38875
RHOJ: JVH1_22090
GJI: H1R19_00440
SANL: KZO11_19400 KZO11_19470
SGRF: SGFS_028000
SHY: SHJG_8629
SHO: SHJGH_8389
SRC: M271_09870
SSOI: I1A49_36865
SVE: SVEN_0489 SVEN_6227
SDV: BN159_2477(pyr9)
SGU: SGLAU_04550
STRE: GZL_02226 GZL_02917
SLD: T261_7912
SRW: TUE45_00621(rbmH_1) TUE45_06418(rbmH_2)
SGS: AVL59_00130
SCAD: DN051_13760
SPHW: NFX46_19275
SNR: SNOUR_09915 SNOUR_12600
SGD: ELQ87_03565
SNQ: CP978_29025
SKA: CP970_02915
SRK: FGW37_26495
SVR: CP971_23945
SPAD: DVK44_09675
SBY: H7H31_23750
SRIM: CP984_09615
SSUB: CP968_16675 CP968_32175
SPHV: F9278_28180
SPAC: B1H29_04715
SCHA: CP983_18380
SNF: JYK04_01553(rbmH)
SPLA: CP981_13855 CP981_21750
SHUN: DWB77_02860(rbmH)
SLIA: HA039_20555
SDD: D9753_04010
SMAO: CAG99_27175
SAOV: G3H79_23740 G3H79_33555
SYAN: NRK68_04400
STUB: MMF93_00210
SCIR: STRCI_006115
SYUN: MOV08_09875 MOV08_12410
SCYN: N8I84_12740
SOV: QZH56_05190 QZH56_16715 QZH56_21230
SHAU: K9S39_20815
SCOA: QU709_17560
STTN: BSL84_04145
STRZ: OYE22_22945
KBU: Q4V64_34035
SARM: DVA86_03350
SPRF: K4G22_30755
STPB: QR97_23405
SRPA: HEP86_14930 HEP86_22875
SMIB: SMIR_00260 SMIR_37550
STRW: QHG49_17495
STRL: HEP84_07605 HEP84_44360 HEP84_54010
STSD: HEP87_45490
KAU: B6264_18520
KCH: O1G21_36975
STRH: GXP74_20075 GXP74_21290
RHAL: LQF10_02755
NFE: HUT17_04640
ACTQ: OG417_42925
SEN: SACE_4928
AOI: AORI_5335
AORI: SD37_34215
ARHD: VSH64_07725
AMYZ: HUW46_09457(rbmH)
PSEQ: AD006_32420
SESP: BN6_32530 BN6_35870
KAL: KALB_2183 KALB_5899 KALB_6285
KUT: JJ691_19090 JJ691_20620
AHM: TL08_07685
UME: RM788_41075
MCRA: ID554_06685
VER: HUT12_06275
MFEU: H1D33_25005
ASE: ACPL_6145(ntaB)
ACTS: ACWT_6013
AOU: ACTOB_004311
DVC: Dvina_05880 Dvina_38690
DAUR: Daura_37835
DMAT: Dmats_05360 Dmats_33650
NHY: JQS43_08500
AG: AEI98660(ctcQ)
 » show all
Reference
PMID:23800859
  Authors
Zhu T, Cheng X, Liu Y, Deng Z, You D
  Title
Deciphering and engineering of the final step halogenase for improved chlortetracycline biosynthesis in industrial Streptomyces aureofaciens.
  Journal
Metab Eng 19:69-78 (2013)
DOI:10.1016/j.ymben.2013.06.003
  Sequence
[ag:AEI98660]
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