KEGG ORTHOLOGY: K21617

ORTHOLOGY: K21617

Entry

K21617                      KO

Symbol

hpbD

Name

4-hydroxyproline betaine 2-epimerase [EC:5.1.1.22]

Reaction

R11630

4-hydroxyproline-betaine 2-epimerase

R11631

proline-betaine 2-epimerase

Brite

KEGG Orthology (KO) [BR:ko00001]
09190 Not Included in Pathway or Brite
  09191 Unclassified: metabolism
   99980 Enzymes with EC numbers
    K21617  hpbD; 4-hydroxyproline betaine 2-epimerase
Enzymes [BR:ko01000]
5. Isomerases
  5.1  Racemases and epimerases
   5.1.1  Acting on amino acids and derivatives
    5.1.1.22  4-hydroxyproline betaine 2-epimerase
     K21617  hpbD; 4-hydroxyproline betaine 2-epimerase

Other DBs

COG:

COG4948

Genes

PSIL:

PMA3_10220

BYI:	BYI23_B014710

BUE:	BRPE67_BCDS01700

MOP:	Mesop_5034

MAM:	Mesau_04624

MAMO:

A6B35_16510

MOH:	IHQ72_33425

MESJ:

MEWS:

MEWM:

MEAA:

AAK:	AA2016_6172

PHT:	BLM14_26775

SFH:	SFHH103_04926

SAME:

SAMCFNEI73_Ch0615

EMX:	FKV68_29025

NGG:	RG540_PA12520

SSUM:

Q9314_23860

LNE:	FZC33_06190

LAP:	ACP90_26460

LABR:

CHH27_13985

LABT:

FIU93_04230(hpbD1)

LAGG:

B0E33_10510

RUT:	FIU92_12385(hpbD4)

RCON:

K3740_09955

LEJ:	ETW24_21190

RPHC:

RZ517_04095

RRL:	RZS32_004775

ASCA:

QEZ52_21185

RSP:

RSP_4007

PDE:

Pden_1187

PYE:	A6J80_02080

PPAN:

ESD82_09180

PVER:

E3U25_13270

PFEO:

E3U26_02065

PTP:	RCA23_c27060

DON:	BSK21_09365

AMYL:

QBD29_17240

MDX:	BTO20_21615 BTO20_21695

ROP:

ROP_23190

RKO:	JWS14_15355

SGRF:

SGFS_097590

ARQ:	BWQ92_13295

GEY:	QMQ05_01360

GOB:

PMAD:

ACTY:

Reference

PMID:24520058

Authors

Kumar R, Zhao S, Vetting MW, Wood BM, Sakai A, Cho K, Solbiati J, Almo SC, Sweedler JV, Jacobson MP, Gerlt JA, Cronan JE

Title

Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine.

Journal

MBio 5:e00933-13 (2014)
DOI:10.1128/mBio.00933-13

Sequence

[pde:Pden_1187] [rsp:RSP_4007]

LinkDB

DBGET integrated database retrieval system