KEGG ORTHOLOGY: K21770

ORTHOLOGY: K21770

Entry

K21770                      KO

Symbol

CCNB2

Name

G2/mitotic-specific cyclin-B2

Pathway

map04068

FoxO signaling pathway

map04110

Cell cycle

map04114

Oocyte meiosis

map04115

p53 signaling pathway

map04218

Cellular senescence

map04914

Progesterone-mediated oocyte maturation

map05166

Human T-cell leukemia virus 1 infection

map05170

Human immunodeficiency virus 1 infection

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K21770  CCNB2; G2/mitotic-specific cyclin-B2
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K21770  CCNB2; G2/mitotic-specific cyclin-B2
   04114 Oocyte meiosis
    K21770  CCNB2; G2/mitotic-specific cyclin-B2
   04115 p53 signaling pathway
    K21770  CCNB2; G2/mitotic-specific cyclin-B2
   04218 Cellular senescence
    K21770  CCNB2; G2/mitotic-specific cyclin-B2
09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    K21770  CCNB2; G2/mitotic-specific cyclin-B2
09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K21770  CCNB2; G2/mitotic-specific cyclin-B2
   05170 Human immunodeficiency virus 1 infection
    K21770  CCNB2; G2/mitotic-specific cyclin-B2
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins
    K21770  CCNB2; G2/mitotic-specific cyclin-B2
   03036 Chromosome and associated proteins
    K21770  CCNB2; G2/mitotic-specific cyclin-B2
DNA replication proteins [BR:ko03032]
Eukaryotic type
  DNA Replication Termination Factors
   Prevention of re-replication factors
    K21770  CCNB2; G2/mitotic-specific cyclin-B2
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Centrosome formation proteins
   Cyclins
    K21770  CCNB2; G2/mitotic-specific cyclin-B2

Other DBs

TC:

1.I.1.1

Genes

HSA:	9133(CCNB2)

PTR:	453478(CCNB2)

PPS:	100982610(CCNB2)

GGO:	101145779(CCNB2)

PON:	100438917(CCNB2)

NLE:	100580621(CCNB2)

HMH:	116463533 116463752

MCC:	702184(CCNB2)

MCF:	101925942(CCNB2)

MTHB:

126958476

MNI:	105489522(CCNB2)

CSAB:

103245548(CCNB2)

CATY:

105601085(CCNB2)

PANU:

101025984 116272568

TGE:	112627365(CCNB2)

MLEU:

105541912(CCNB2)

RRO:	104670890(CCNB2)

RBB:	108544822(CCNB2)

TFN:	117070585(CCNB2)

PTEH:

111547435 111553698(CCNB2)

CANG:

105510613(CCNB2) 105515200

CJC:	100388842(CCNB2)

SBQ:	101027967 101044389(CCNB2)

CIMI:

108306824(CCNB2)

CSYR:

103263816(CCNB2)

MMUR:

105881385(CCNB2)

LCAT:

123623354(CCNB2)

PCOQ:

105821367(CCNB2)

OGA:	100964113(CCNB2)

MMU:	12442(Ccnb2)

MCAL:

110301402(Ccnb2)

MPAH:

110327463(Ccnb2)

RNO:	363088(Ccnb2)

MCOC:

116073048(Ccnb2)

ANU:	117699767(Ccnb2)

MUN:	110560855(Ccnb2)

CGE:	100773656(Ccnb2)

MAUA:

101833257(Ccnb2)

PROB:

127231944(Ccnb2)

PLEU:

114690838(Ccnb2)

MORG:

121466142(Ccnb2)

MFOT:

126491618

AAMP:

119809842(Ccnb2)

NGI:	103737154(Ccnb2)

HGL:	101696424(Ccnb2)

CPOC:

100716328(Ccnb2)

CCAN:

109693840(Ccnb2)

DORD:

105980951(Ccnb2)

DSP:	122114500(Ccnb2)

PLOP:

125340324(Ccnb2)

NCAR:

124970575

MMMA:

107138063(Ccnb2)

OCU:

100357416

OPI:	101529581(CCNB2)

TUP:	102501319(CCNB2)

GVR:	103593976(CCNB2) 103602482

CFA:	478324(CCNB2)

CLUD:

112675843(CCNB2)

VVP:	112917134(CCNB2)

VLG:	121484861(CCNB2)

NPO:	129506320(CCNB2)

AML:	100475507(CCNB2)

UMR:	103676798(CCNB2)

UAH:	113269684(CCNB2)

UAR:	123784090(CCNB2)

ELK:

111153254

LLV:

125104007

MPUF:

101670335(CCNB2)

MNP:	131999246(CCNB2)

MLK:	131835871(CCNB2)

NVS:	122893639(CCNB2)

ORO:	101362162(CCNB2) 101366345

EJU:	114206445(CCNB2)

ZCA:	113910151(CCNB2)

MLX:	118003405(CCNB2)

NSU:	110583874(CCNB2)

LWW:

102745274

FCA:	101080972(CCNB2)

PYU:	121041777(CCNB2)

PCOO:

112855416(CCNB2)

PBG:	122468577(CCNB2)

PVIV:

125169039(CCNB2)

LRUF:

124508045

PTG:	102951958(CCNB2)

PPAD:

109262912(CCNB2)

PUC:	125910050 125937565

AJU:

106973791

HHV:	120230878(CCNB2)

BTA:	281668(CCNB2)

BOM:	102284855(CCNB2)

BIU:	109565083(CCNB2)

BBUB:

102398229(CCNB2)

BBIS:

104986304(CCNB2)

CHX:	102179856(CCNB2)

OAS:	101115712(CCNB2)

BTAX:

128054390(CCNB2)

ODA:	120853048(CCNB2)

CCAD:

122443546(CCNB2)

MBEZ:

129563160(CCNB2)

SSC:	100135668(CCNB2)

CFR:	102523319(CCNB2)

CBAI:

105080458(CCNB2)

CDK:	105088978(CCNB2)

VPC:	102525211(CCNB2)

BACU:

103012622(CCNB2)

BMUS:

118890364(CCNB2)

LVE:	103068910(CCNB2)

OOR:	101277999(CCNB2)

DLE:	111177576(CCNB2)

PCAD:

102975742(CCNB2) 102991290

PSIU:

116750003(CCNB2)

NASI:

112393128(CCNB2)

ECB:	100054413(CCNB2)

EPZ:	103555305(CCNB2)

EAI:	106827458(CCNB2)

MYB:	102261943(CCNB2)

MYD:	102775345(CCNB2)

MMYO:

118652951(CCNB2)

MLF:	102441382(CCNB2)

PKL:	118720439(CCNB2)

EFUS:

103283847(CCNB2)

MNA:	107533754(CCNB2)

DRO:	112311449(CCNB2)

SHON:

118992267(CCNB2)

AJM:	119053500(CCNB2)

PDIC:

114492336(CCNB2)

PHAS:

123808416(CCNB2)

MMF:	118639800(CCNB2)

PPAM:

129063515(CCNB2) 129083911

HAI:	109390689(CCNB2)

RFQ:	117022749(CCNB2)

PALE:

102892539(CCNB2)

PGIG:

120604578(CCNB2)

PVP:	105294273(CCNB2)

RAY:	107501075(CCNB2)

MJV:	108386652(CCNB2)

TOD:	119238676(CCNB2) 119253287

SARA:

101558034(CCNB2)

SETR:

126009272(CCNB2)

LAV:	100659655(CCNB2)

TMU:

101346906

ETF:	101641440(CCNB2)

DNM:	101413586(CCNB2)

MDO:	100019727(CCNB2)

GAS:	123236114(CCNB2)

SHR:	100931176(CCNB2)

AFZ:

127551202

PCW:	110205363(CCNB2)

OAA:	100091100(CCNB2)

GGA:	415400(CCNB2)

PCOC:

116244648(CCNB2)

MGP:	100542909(CCNB2)

CJO:	107318514(CCNB2)

TPAI:

128075103(CCNB2)

LMUT:

125697975(CCNB2)

NMEL:

110403959(CCNB2)

APLA:

101792974(CCNB2)

ACYG:

106033711(CCNB2)

CATA:

118251724(CCNB2)

AFUL:

116493403(CCNB2)

TGU:	100225413(CCNB2)

LSR:	110471415(CCNB2)

SCAN:

103815979(CCNB2)

PMOA:

120508866(CCNB2)

OTC:	121343372(CCNB2)

PRUF:

121354608(CCNB2)

GFR:	102044449(CCNB2)

FAB:	101815219(CCNB2)

OMA:	130257395(CCNB2)

PHI:	102109952(CCNB2)

PMAJ:

107209184(CCNB2)

CCAE:

111934176(CCNB2)

CCW:	104683825(CCNB2)

CBRC:

103618644(CCNB2)

ETL:	114056383(CCNB2)

ZAB:	102072889(CCNB2)

ACHL:

103801751(CCNB2)

SVG:	106851791(CCNB2)

MMEA:

130584516(CCNB2)

HRT:	120758531(CCNB2)

FPG:	101913711(CCNB2)

FCH:	102054317(CCNB2)

CLV:	102084928(CCNB2)

EGZ:	104130767(CCNB2)

NNI:	104016845(CCNB2)

PCRI:

104026259(CCNB2)

PLET:

104614647(CCNB2)

EHS:	104502971(CCNB2)

PCAO:

104048214(CCNB2)

ACUN:

113484014(CCNB2)

TALA:

104357568(CCNB2)

PADL:

103914879(CCNB2)

AFOR:

103899878(CCNB2)

ACHC:

115341856(CCNB2)

HALD:

104312168(CCNB2)

HLE:	104834454(CCNB2)

AGEN:

126043964

GCL:

127020482

CCRI:

104155495(CCNB2)

CSTI:

104549752(CCNB2)

CMAC:

104479850(CCNB2)

MUI:	104537463(CCNB2)

BREG:

104636380(CCNB2)

FGA:	104070349(CCNB2)

GSTE:

104250869(CCNB2)

LDI:	104339792(CCNB2)

MNB:	103770460(CCNB2)

OHA:	104330517(CCNB2)

NNT:	104410076(CCNB2)

SHAB:

115612864(CCNB2)

DPUB:

104309872(CCNB2)

PGUU:

104457876(CCNB2)

ACAR:

104519563(CCNB2)

CPEA:

104385997(CCNB2)

AVIT:

104267721(CCNB2)

CVF:	104287083(CCNB2)

RTD:	128914894(CCNB2)

CUCA:

104054368(CCNB2)

TEO:	104369849(CCNB2)

BRHI:

104488082(CCNB2)

AROW:

112974731(CCNB2)

NPD:	112952880(CCNB2)

TGT:	104573596(CCNB2)

DNE:	112991097(CCNB2)

SCAM:

104148426(CCNB2)

ASN:	102376865(CCNB2)

AMJ:	102564267(CCNB2)

CPOO:

109308968(CCNB2)

GGN:	109288652(CCNB2)

PSS:	102454875(CCNB2)

CMY:	102945031(CCNB2)

CCAY:

125644101(CCNB2)

DCC:	119863023(CCNB2)

CPIC:

101949268(CCNB2)

TST:	117884308(CCNB2)

CABI:

116826696(CCNB2)

MRV:	120374157(CCNB2)

PVT:	110074534(CCNB2)

SUND:

121932601(CCNB2)

VKO:	123027625(CCNB2)

PMUA:

114584927(CCNB2)

PRAF:

128401350(CCNB2)

ZVI:	118093314(CCNB2)

HCG:	128334799(CCNB2)

GJA:	107117975(CCNB2)

STOW:

125424465(CCNB2)

EMC:	129345554(CCNB2)

XLA:	397743(ccnb2.S) 398162 398888(ccnb2.L)

XTR:	100270772(ccnb2) 394448

NPR:	108793323(CCNB2)

RTEM:

120931386(CCNB2)

BBUF:

120986379 120987154

BGAR:

122925737 122929660

MUO:	115458866(CCNB2)

GSH:	117348597(CCNB2)

DRE:	368316(ccnb2)

SRX:	107750496 107755008 107755053

SANH:

107670740 107679007 107700435

SGH:	107572729 107586027 107595094 107595096

CCAR:

109085553 109087909 109103287 109113699(ccnb2)

CAUA:

113051529 113051906 113061851 113105943 113118589

CGIB:

127961597 128016970

PTET:

122348316(ccnb2)

LROH:

127167664(ccnb2)

OMC:	131543753(ccnb2)

PPRM:

120491363(ccnb2)

RKG:	130069926(ccnb2)

MAMB:

125264722(ccnb2)

CIDE:

127515821

MASI:

127409673 127444570

TROS:

130557532(ccnb2)

TDW:	130423376(ccnb2)

MANU:

129442858(ccnb2)

IPU:

108259243

IFU:	128602628(ccnb2)

PHYP:

113540823(ccnb2)

SMEO:

124379902(ccnb2)

TFD:	113636727(ccnb2)

TVC:	132838665(ccnb2)

AMEX:

103043733

CMAO:

118817342(ccnb2)

EEE:	113575732(ccnb2)

CHAR:

105899498(ccnp) 105910390(ccnb2)

TRU:	101065671 101074416 101076205

TFS:	130514798 130518756 130535622(ccnp)

TNG:	GSTEN00008349G001

LCO:	104935752 104935762 104940520

NCC:	104947913 104949206(cntd2) 104953225(ccnb2)

TBEN:

117470186(ccnp) 117472241 117472243

CGOB:

115006426 115006427 115006436 115017921

PGEO:

117457710(ccnp) 117463717 117463807 117466207

GACU:

117533657 117551767(ccnp) 117557835 117557839

EMAC:

134863038 134863742 134879858(ccnp)

ELY:	117251020 117259830(ccnp) 117272671

EFO:	125881056 125881064 125889518

PLEP:

121940759 121943540

SLUC:

116046535 116067258 116067288

ECRA:

117942415(ccnp) 117954749

ESP:	116673365 116685783 116685784

PFLV:

114548494 114552441 114552598

GAT:	120809226(ccnb2) 120812945 120816726

PPUG:

119193944 119199458(ccnb2) 119211129

AFB:	129094805(ccnp) 129101484 129101764

CLUM:

117728654 117728839 117741719(ccnp)

PSWI:

130192721(ccnb2) 130210498(ccnp)

MSAM:

119882693 119889984(ccnb2) 119890537

SCHU:

122878453 122879039 122881991

CUD:	121514400(ccnb2) 121515498

ALAT:

119017612 119017850 119032268

MZE:

101472628

ONL:

100692470

OAU:	116334318(ccnb2)

OLA:	100049213(ccnb2) 101162061

OML:	112149155(ccnp) 112161035(ccnb2)

CSAI:

133418567 133421575 133422026 133442263(ccnp)

XMA:	102226168 102227543(cntd2)

XCO:	114143200 114161604

XHE:	116716143 116718627 116737532

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122824214(ccnb2) 122832318

PPRL:

129352204 129355526 129359024(ccnp)

CVG:	107083462 107085054 107090914

CTUL:

119771839 119779042 119799069

GMU:	124866658 124867029 124883781

NFU:

107381480

KMR:	108238152(ccnp) 108250664(ccnb2)

ALIM:

106525628 106532053

NWH:

119410838

AOCE:

111564411(ccnb2) 111566098

MCEP:

125005256(ccnb2) 125013340

CSEM:

103377650(cntd2) 103379018

POV:	109634457 109647535

SSEN:

122771949(ccnb2) 122773770

HHIP:

117752035(ccnb2) 117772338(ccnp)

HSP:	118106162(ccnb2) 118106347

SMAU:

118299287

LCF:	108894246 108894316 108898800(ccnp)

SDU:	111223818(ccnb2) 111233412

SLAL:

111656616(ccnb2) 111665458(cntd2)

XGL:	120792002 120795915 120804146

HCQ:	109514392 109526230(cntd2)

SSCV:

125966766 125972509

SBIA:

133504620(ccnp)

PEE:	133405303(ccnp) 133415008 133415069

PTAO:

133474465 133474479 133482793(ccnp)

BPEC:

110168039 110168041

MALB:

109951232(ccnb2) 109951260 109960384(cntd2)

BSPL:

114852063 114852252 114868713(ccnp)

SJO:	128354936(ccnb2) 128359842(ccnp)

SASA:

106587338(ccnb2)

STRU:

115163682(cntd2) 115167247

OTW:	112249181 112263712(ccnb2)

OMY:	100136691 110506532 110507995(ccnp)

OGO:	123993890 124033750 124035731

ONE:	115112265 115113650 115136595(cntd2)

OKI:	109887808 109895385(ccnb2) 109905879(cntd2)

OKE:	118381432(ccnb2) 118393869 118397567(ccnp)

SALP:

111969379 112073542

SNH:	120018972 120047174(ccnb2)

CCLU:

121558906(ccnb2)

ELS:	105016586(ccnb2) 105023569(cntd2)

SFM:	108926728(ccnb2) 108931146

PKI:	111844972(ccnb2) 111846694 111860540(cntd2)

AANG:

118226951(ccnb2)

LOC:	102684789(ccnb2)

PSPA:

121294513 121299044 121304856

ARUT:

117414910 117428092 117429551(ccnb2) 117435703

PSEX:

120541798(ccnb2)

LCM:	102349107(CCNB2)

CMK:	103187043(ccnb2)

RTP:	109914894(ccnb2)

CPLA:

122541009(ccnb2)

HOC:	132834405(ccnb2)

LERI:

129712632(ccnb2)

PMRN:

116938505(CCNB2)

LRJ:	133346475(CCNB2)

BBEL:

109470771

CIN:

100184393

SCLV:

120328162 120337779 120343821

SPU:

LPIC:

APLC:

AJC:

SKO:	100303572(ccnb)

DME:	Dmel_CG3510(CycB)

DER:

6547341

DSE:

6615597

DSI:	Dsimw501_GD15503(Dsim_GD15503)

DYA:	Dyak_GE11834

DAN:

6494190

DSR:	110177323 110184934

DPO:	4803852 6896812 6902947

DPE:	6588946 6590086 6595015

DMN:	108154032 108160187 108163228 117185730 117186389 117186398 117186408 117186473 117187064

DWI:

6640285

DGR:	6559129 6565568 6569391

DMO:	Dmoj_GI19224

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:	108376339 108377127

AOQ:

129245404

TDA:	119664174 119673814 119673815 119673816 119673817 119673820 119673821

MDE:	101895010 131803899

SCAC:

106087763

LCQ:

111681409

LSQ:

119604443

GFS:	119631805 119636754 119639970 119642485

ECOE:

129951563

CLON:

129611101

HIS:

119647425

AGA:	1275773 1275774

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AAG:

AALB:

CQU:	CpipJ_CPIJ010895

CPII:

CNS:

BCOO:

ACER:

BIM:

BTER:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

NVI:	100122223(cycB)

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

VCAN:

TCA:

DPA:

AGRG:

ATD:	109598605 109598608 109609128 109609179

AGB:

108908676

LDC:	111505016 111505022 111515407 111516750

NVL:	108559549 108561011 108564611

APLN:

108733614 108743361 112906187

PPYR:

BMOR:

BMAN:

MSEX:

DPL:	KGM_203845 KGM_203846

BANY:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:	105387126 105395764

PGW:

API:

DNX:

AGS:

RMD:

BTAB:

DCI:

CLEC:

106663209 106666329 106667243 106668540

HHAL:

106684216 106686392 106689518

NLU:

111052266

HVI:	124355478 124355493

MQU:	128996352 128997277

PHU:	Phum_PHUM128990

TPAL:

117640131 117646106 117648028

ZNE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_206150 DAPPUDRAFT_222925 DAPPUDRAFT_299529 DAPPUDRAFT_442518

DMK:	116915884 116928802

DPZ:	124328285 124336263

PCHN:

PCLA:

CQD:

HAZT:

EAF:	111701350 111702910 111706711 111709380

LSM:

121124465

TCF:

131888190

PPOI:

119100879

DSV:	119448553 119448563 119449171 119449186 119459338

RSAN:

119395900

RMP:	119174253 119185699

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

LPOL:

PMEO:

TSP:

HRO:	HELRODRAFT_106476

LGI:	LOTGIDRAFT_164886

PVUL:

126817611

PCAN:

112553650

BGT:	106062617 106074749

GAE:	121372667 121383689

CRG:	105317174 105326680 117689045

CVN:	111106887 111131322 111131500

CANU:

128158020 128177950

OED:	125651874 125656156

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:	106167570 106181597

SMM:	Smp_082490

OVI:	T265_04198

EGL:

EGR_05081

NVE:

5505740

EPA:	110237193 110244190

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:	114529418 114533795

XEN:	124452148 124457222

HMG:

100204331

AQU:

105312818

MBR:	MONBRDRAFT_8459(cycB)

SRE:	PTSG_05912

EHI:	EHI_166420(125.t00008)

EDI:	EDI_272880

EIV:	EIN_171050

TET:	TTHERM_00189230

PTM:	GSPATT00005339001 GSPATT00009078001 GSPATT00018079001 GSPATT00028960001

» show all

Reference

PMID:17533373

Authors

Bellanger S, de Gramont A, Sobczak-Thepot J

Title

Cyclin B2 suppresses mitotic failure and DNA re-replication in human somatic cells knocked down for both cyclins B1 and B2.

Journal

Oncogene 26:7175-84 (2007)
DOI:10.1038/sj.onc.1210539

Sequence

[hsa:9133]

Reference

PMID:8375336

Authors

Chapman DL, Wolgemuth DJ

Title

Isolation of the murine cyclin B2 cDNA and characterization of the lineage and temporal specificity of expression of the B1 and B2 cyclins during oogenesis, spermatogenesis and early embryogenesis.

Journal

Development 118:229-40 (1993)

Sequence

[mmu:12442]

LinkDB

DBGET integrated database retrieval system