KEGG   ORTHOLOGY: K21783
Entry
K21783                      KO                                     
Symbol
pigJ, redX
Name
beta-ketoacyl ACP synthase [EC:2.3.1.-]
Pathway
map00333  Prodigiosin biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
M00838  Undecylprodigiosin biosynthesis, L-proline => undecylprodigiosin
Reaction
R11665  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00333 Prodigiosin biosynthesis
    K21783  pigJ, redX; beta-ketoacyl ACP synthase
Other DBs
COG: COG3321
Genes
SMW: SMWW4_v1c10950(pigJ)
SRR: SerAS9_1744
SRS: SerAS12_1744
SRA: SerAS13_1745
SERF: L085_23075
SERM: CLM71_22565
SSUR: ATE40_002190
SNEM: NLX84_05460
SERA: Ser39006_020650
SERQ: CWC46_20655
PROD: PCO85_04895
VGA: BSQ33_01000
VSR: Vspart_01687
VRU: RND59_13745
PRR: AT705_06625
PTU: PTUN_a2938(cfa6)
PXI: J5O05_20805
PVB: J5X90_18255
PSAZ: PA25_35570
HCH: HCH_06033
HAHE: ENC22_25990
HAHH: O5O45_30015
HPRO: LMS44_05410
CARI: FNU76_06125
CCUP: BKK81_22630
KIA: G8A07_12230
PAQA: K9V56_011390
RUG: QC826_01040
MIWA: SS37A_37710
NTP: CRH09_26875
SCO: SCO5878(redX)
SLV: SLIV_09215
SGM: GCM10017557_78280
STRD: NI25_09840
SSIA: A7J05_21375
SALF: SMD44_07474
SRK: FGW37_26870
SPAD: DVK44_31040
SSPB: CP982_34515
SFEU: IM697_31000
SLF: JEQ17_02475
SAOV: G3H79_04155
STUB: MMF93_27605
SFP: QUY26_05275
ARUB: J5A65_13320
AMAZ: LUW76_14365
AG: CAH55638(pigJ)
 » show all
Reference
PMID:15853884
  Authors
Williamson NR, Simonsen HT, Ahmed RA, Goldet G, Slater H, Woodley L, Leeper FJ, Salmond GP
  Title
Biosynthesis of the red antibiotic, prodigiosin, in Serratia: identification of a novel 2-methyl-3-n-amyl-pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces.
  Journal
Mol Microbiol 56:971-89 (2005)
DOI:10.1111/j.1365-2958.2005.04602.x
  Sequence
[ag:CAH55638]
Reference
PMID:15528645
  Authors
Harris AK, Williamson NR, Slater H, Cox A, Abbasi S, Foulds I, Simonsen HT, Leeper FJ, Salmond GP
  Title
The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species- and strain-dependent genome context variation.
  Journal
Microbiology 150:3547-60 (2004)
DOI:10.1099/mic.0.27222-0
  Sequence
[ag:CAH55638]
LinkDB

KEGG   REACTION: R11665
Entry
R11665                      Reaction                               
Definition
Pyrrole-2-carbonyl-[pcp] + Acyl-carrier protein <=> Pyrrolyl-2-carboxyl-S-[acyl-carrier protein] + Peptidyl-carrier protein
Equation
C12483 + C00229 <=> C21567 + C21097
Enzyme
2.3.1.-
Pathway
rn00333  Prodigiosin biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
M00838  Undecylprodigiosin biosynthesis, L-proline => undecylprodigiosin
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.-
     R11665  Pyrrole-2-carbonyl-[pcp] + Acyl-carrier protein <=> Pyrrolyl-2-carboxyl-S-[acyl-carrier protein] + Peptidyl-carrier protein
Orthology
K21783  beta-ketoacyl ACP synthase [EC:2.3.1.-]
Reference
1  [PMID:15853884]
  Authors
Williamson NR, Simonsen HT, Ahmed RA, Goldet G, Slater H, Woodley L, Leeper FJ, Salmond GP
  Title
Biosynthesis of the red antibiotic, prodigiosin, in Serratia: identification of a novel 2-methyl-3-n-amyl-pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces.
  Journal
Mol Microbiol 56:971-89 (2005)
DOI:10.1111/j.1365-2958.2005.04602.x
LinkDB

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