KEGG ORTHOLOGY: K21803

ORTHOLOGY: K21803

Entry

K21803                      KO

Symbol

METTL21B, EEF1AKMT3

Name

EEF1A lysine methyltransferase 3 [EC:2.1.1.-]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03012 Translation factors
    K21803  METTL21B, EEF1AKMT3; EEF1A lysine methyltransferase 3
Translation factors [BR:ko03012]
Eukaryotic type
  Elongation factors
   Elongation associated factors
    K21803  METTL21B, EEF1AKMT3; EEF1A lysine methyltransferase 3

Other DBs

GO:

0016279

Genes

HSA:	25895(EEF1AKMT3)

PTR:	107966350(EEF1AKMT3)

PPS:	134728362(EEF1AKMT3)

GGO:	101148750(EEF1AKMT3)

PON:	100444644(EEF1AKMT3)

PPYG:

129009553(EEF1AKMT3)

NLE:	100592795(EEF1AKMT3)

HMH:	116480844(EEF1AKMT3)

SSYN:

129465891(EEF1AKMT3)

MCC:	712519(EEF1AKMT3)

MCF:	102118073(EEF1AKMT3)

MNI:	105474077(EEF1AKMT3)

CSAB:

103238592(METTL21B)

CATY:

105587236(METTL21B)

PANU:

101011697(EEF1AKMT3)

TGE:	112635432(EEF1AKMT3)

MLEU:

105545591(METTL21B)

RRO:	104682340(EEF1AKMT3)

TFN:	117089859(EEF1AKMT3)

PTEH:

111541788(EEF1AKMT3)

CANG:

105500483(METTL21B)

CJC:	100389321(EEF1AKMT3)

SBQ:	101043418(METTL21B)

CIMI:

108309748(EEF1AKMT3)

ANAN:

105729116(EEF1AKMT3)

CSYR:

103264461(EEF1AKMT3)

MMUR:

105878004(EEF1AKMT3)

PCOQ:

105816808(METTL21B)

OGA:	100962263(EEF1AKMT3)

MMU:	100504608(Eef1akmt3)

MCAL:

110304064(Eef1akmt3)

MPAH:

110326523(Eef1akmt3)

RNO:	679247(Eef1akmt3)

ASYL:

127670694(Eef1akmt3)

MUN:	110561687(Eef1akmt3)

CGE:	100761001(Eef1akmt3)

MAUA:

101834484(Eef1akmt3)

PROB:

127215689(Eef1akmt3)

PLEU:

114704824(Eef1akmt3)

MORG:

121459889(Eef1akmt3)

MFOT:

126514763

AAMP:

119803411(Eef1akmt3)

NGI:	103742894(Mettl21b)

HGL:	101699642(Mettl21b)

CPOC:

100717122(Eef1akmt3)

CCAN:

109686213(Eef1akmt3)

DORD:

105990165(Mettl21b)

DSP:	122124357(Eef1akmt3)

PLOP:

125362028(Eef1akmt3)

NCAR:

124982465

MMMA:

107140111(Eef1akmt3)

ITI:	101960510(Eef1akmt3)

OCU:	100347094(EEF1AKMT3) 127486366

OPI:	101523272(EEF1AKMT3)

TUP:	102492050(METTL21B)

GVR:	103588485(METTL21B)

CFA:	111097837(EEF1AKMT3)

VVP:	112922211(EEF1AKMT3)

VLG:	121491056(EEF1AKMT3)

NPO:	129511344(EEF1AKMT3)

AML:	100481985(EEF1AKMT3)

UMR:	103656943(EEF1AKMT3)

UAH:	113256362(EEF1AKMT3)

UAR:	123787199(EEF1AKMT3)

ELK:

111160178

LLV:

125106502

MPUF:

101673559(METTL21B)

MNP:	132019861(EEF1AKMT3)

MLK:	131838538(EEF1AKMT3)

NVS:	122892191(EEF1AKMT3)

ORO:	101364000(METTL21B)

EJU:	114215040(EEF1AKMT3)

ZCA:	113922555(EEF1AKMT3)

MLX:	118008654(EEF1AKMT3)

NSU:	110577863(EEF1AKMT3)

LWW:	102745676(EEF1AKMT3)

FCA:	101098642(EEF1AKMT3)

PYU:	121040855(EEF1AKMT3)

PCOO:

112863874(EEF1AKMT3)

PBG:	122473839(EEF1AKMT3)

PVIV:

125169983(EEF1AKMT3)

LRUF:

124501750

LGF:	123591102(EEF1AKMT3)

AJU:	106975876(EEF1AKMT3)

PTG:	102971936(METTL21B)

PPAD:

109270397(METTL21B)

PUC:

125919266

PLEZ:

122224755(EEF1AKMT3)

HHV:	120248030(EEF1AKMT3)

BTA:	100125307(EEF1AKMT3)

BOM:	102277701(EEF1AKMT3)

BIU:	109559304(METTL21B)

BBUB:

102414894(EEF1AKMT3)

BBIS:

104999638(METTL21B)

CHX:	102170490(METTL21B)

OAS:	101115529(EEF1AKMT3)

BTAX:

128047782(EEF1AKMT3)

CSUM:

138079306(EEF1AKMT3)

ODA:	120857511(EEF1AKMT3)

CCAD:

122427217(EEF1AKMT3)

MREE:

136167274(EEF1AKMT3)

OVR:	110124873(EEF1AKMT3)

MBEZ:

129537205(EEF1AKMT3)

SSC:	100625070(EEF1AKMT3)

CFR:	102523320(EEF1AKMT3)

CBAI:

105062144(METTL21B)

CDK:	105100324(EEF1AKMT3)

VPC:	102533311(EEF1AKMT3)

BACU:

103003487(METTL21B)

BMUS:

118901859(EEF1AKMT3)

LVE:	103083999(METTL21B)

OOR:	101284763(EEF1AKMT3)

LALB:

132529367(EEF1AKMT3)

DLE:	111173821(EEF1AKMT3)

PCAD:

102983845(EEF1AKMT3)

PSIU:

116760656(EEF1AKMT3)

NASI:

112394411(EEF1AKMT3)

ECB:	100053809(EEF1AKMT3)

EPZ:	103553642(EEF1AKMT3)

EAI:	106833022(EEF1AKMT3)

MYB:	102262014(METTL21B)

MYD:	102772067(METTL21B)

MMYO:

118649580(EEF1AKMT3)

MLF:	102429713(EEF1AKMT3)

MDT:	132227837(EEF1AKMT3)

MYUM:

139006967(EEF1AKMT3)

PKL:	118730278(EEF1AKMT3)

EFUS:

103292482(EEF1AKMT3)

MNA:	107546168(METTL21B)

DRO:	112319033(EEF1AKMT3)

SHON:

118975894(EEF1AKMT3)

AJM:	119065241(EEF1AKMT3)

PDIC:

114512973(EEF1AKMT3)

PHAS:

123812753(EEF1AKMT3)

MMF:	118623550(EEF1AKMT3)

PPAM:

129075826(EEF1AKMT3)

HAI:	109390758(METTL21B)

RFQ:	117028660(EEF1AKMT3)

PALE:

102895576(EEF1AKMT3)

PGIG:

120604976(EEF1AKMT3)

PVP:	111732801(EEF1AKMT3)

RAY:	107501494(EEF1AKMT3)

MJV:	108388600(EEF1AKMT3)

TOD:	119248106(EEF1AKMT3)

SARA:

101537160(METTL21B)

SFUM:

130026986(EEF1AKMT3)

SETR:

126022247(EEF1AKMT3)

LAV:	100662357(EEF1AKMT3)

TMU:

101354521

ETF:	101645914(EEF1AKMT3)

DNM:	101413543(EEF1AKMT3)

MDO:	100031516(METTL21B)

GAS:	123248901(EEF1AKMT3)

SHR:	100914489(EEF1AKMT3)

AFZ:

127537927

PCW:	110210994(EEF1AKMT3)

TVP:	118849767(EEF1AKMT3)

PBRV:

138155330(EEF1AKMT3)

OAA:	100086107(EEF1AKMT3)

TACU:

119933369(EEF1AKMT3)

MGP:

104915926

CJO:	107325804(EEF1AKMT3)

NMEL:

110389213(EEF1AKMT3)

TGU:	115491443(EEF1AKMT3)

PMOA:

120499469(EEF1AKMT3)

OTC:	121334265(EEF1AKMT3)

ATRC:

139604830(EEF1AKMT3)

OMA:	130265803(EEF1AKMT3)

PHI:	106628663(METTL21B)

PMAJ:

107199189

ACOE:

138100093(EEF1AKMT3)

ZLE:	135459032(EEF1AKMT3)

SVG:	106862651(METTL21B)

MMEA:

130588044

HRT:

120748274

SATI:

136372738(EEF1AKMT3)

CCIC:

134054938(EEF1AKMT3)

SHAB:

115618761(EEF1AKMT3)

TALA:

116962725(EEF1AKMT3)

ACHC:

115351404(EEF1AKMT3)

AGEN:

126037405

CBOY:

140644485(EEF1AKMT3)

AROW:

112972147(EEF1AKMT3)

NPD:	112952265(EEF1AKMT3)

DNE:

112991462

ASN:	102383408(EEF1AKMT3)

AMJ:	102572095(METTL21B)

CPOO:

109324471(METTL21B)

GGN:	109293384(METTL21B)

PSS:	102443354(EEF1AKMT3)

CMY:	102946576(EEF1AKMT3)

CCAY:

125627528(EEF1AKMT3) 125644045

DCC:	119845875(EEF1AKMT3)

CPIC:

101953808(EEF1AKMT3)

TST:	117889235(EEF1AKMT3)

CABI:

116828442(EEF1AKMT3)

MRV:	120391043(EEF1AKMT3)

ACS:	100560111(mettl21b)

ASAO:

132767648(EEF1AKMT3)

PVT:	110074440(EEF1AKMT3)

SUND:

121924424(EEF1AKMT3)

PBI:	103060156(EEF1AKMT3)

PMUR:

107291531(EEF1AKMT3)

CTIG:

120297688(EEF1AKMT3)

PGUT:

117662684(EEF1AKMT3)

APRI:

131192364(EEF1AKMT3)

PTEX:

113445535(EEF1AKMT3)

NSS:	113418442(EEF1AKMT3)

VKO:	123029910(EEF1AKMT3)

PMUA:

114593029(EEF1AKMT3)

PRAF:

128405765(EEF1AKMT3)

ZVI:	118078881 118079018(EEF1AKMT3)

HCG:	128344581(EEF1AKMT3)

GJA:	107119672(METTL21B)

STOW:

125430241(EEF1AKMT3)

EMC:	129346593(EEF1AKMT3)

XLA:	108708602(eef1akmt3.L)

XTR:	549414(eef1akmt3)

NPR:	108791592(METTL21B)

RTEM:

120929437(EEF1AKMT3)

ACAT:

141127374(EEF1AKMT3)

BBUF:

120996177(EEF1AKMT3)

BGAR:

122932153(EEF1AKMT3)

DTC:	141091283(EEF1AKMT3)

PWL:	138299860(EEF1AKMT3)

MUO:	115466782(EEF1AKMT3)

GSH:	117356638(EEF1AKMT3)

SRX:	107747833(mettl21b)

SANH:

107684011

SGH:	107561789(mettl21b) 107567942

CCAR:

109089186(eef1akmt3)

CAUA:

113068163(eef1akmt3)

CGIB:

PTET:

LROH:

OMC:

PPRM:

RKG:

MAMB:

CIDE:

CERY:

IPU:	108254795(eef1akmt3)

IFU:

128625243

TFD:

125140763

TRN:

134301841

AMEX:

103037821(eef1akmt3)

CMAO:

118799679

EEE:	113572446(eef1akmt3)

CHAR:

105897879(eef1akmt3)

SPIL:

LCO:

TBEN:

PGEO:

GACU:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

ECRA:

ESP:	116679873 116687617

PFLV:

114553808(eef1akmt3)

GAT:

PPUG:

AFB:

CANA:

CVE:

MSAM:

SCHU:

CUD:

SPUL:

LMIX:

ALAT:

ASTR:

MZE:	101486571(eef1akmt3)

ONL:	100690720(eef1akmt3)

OAU:

116329887

OLA:	101165051(eef1akmt3)

OML:

CSAI:

XMA:

XCO:

XHE:

PRET:

103465298(mettl21b)

PFOR:

103144291(mettl21b)

PLAI:

106954722(mettl21b)

PMEI:

106928156

GAF:

122834645

PPRL:

129358543

CVG:	107099679(mettl21b)

CTUL:

119791793

GMU:

124857278

NFU:	107385619(mettl21b)

KMR:	108235678(eef1akmt3)

ALIM:

106513279(mettl21b)

NWH:

AOCE:

EJA:

BFRE:

MCEP:

CSEM:

103386023(mettl21b)

POV:	109629377(mettl21b)

SSEN:

SSOE:

HHIP:

HSP:

PPLT:

SMAU:

LCF:	108898908(eef1akmt3)

SDU:	111221497(eef1akmt3)

SLAL:

111667862(eef1akmt3)

XGL:

120807206

HCQ:	109522257(mettl21b)

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

110171332(eef1akmt3)

ENY:

140365938

MALB:

109955964(eef1akmt3)

BSPL:

SJO:

SSCO:

SASA:

STRU:

115150445(eef1akmt3)

OTW:

OMY:

OGO:

ONE:

OKI:	109890245(eef1akmt3)

OKE:

118399786

OMM:

135541822

OCLA:

139414384

SALP:

111970221(eef1akmt3)

SNH:

120064573

CCLU:

121578576

ELS:	105016945(eef1akmt3)

SFM:	108918368(eef1akmt3)

PKI:	111854880(eef1akmt3)

AANG:

118210545

AROT:

135237966

CCOG:

133110352

LOC:	102685721(mettl21b)

PSPA:

121308966

ARUT:

117401009 117966993

PSEX:

120524847

LCM:	102346849(METTL21B)

CMK:	103186803 103187501 103187502 103187503 103187504 103187505 103187506 103187529 103187530 103187532

RTP:	109911039 109911883 109913617 109916748 109916749 109916750 109916751 109916752 109916753 109922459 109924353 109936260 109938241 125483792

CPLA:

122543274 122544229 122553994 122553995 122553996 122553998 122554017 122554018 122554019 122554020 122554021 122554022 122554026 122555632 122555639 122556248

HOC:	132805762 132818035 132818039 132818042 132818043 132818044 132818045 132818046 132818047 132818048 132818049 132818050 132821660 132821707 132821712 132833904

LERI:

129694626 129699948 129700432 129700445 129700446 129700447 129700448 129700449 129700450 129703277 129703421 129703423 129710409 129715237 129715514

HAKA:

140715555 140715556 140723526 140723533 140724559 140724560 140741303

MIS:	MICPUN_55638

CNB:

CNBE3050

CGI:	CGB_E4050C

EHX:	EMIHUDRAFT_219908

DSD:	GD606_01825

DRT:

Dret_1737

DSF:

UWK_00430

DOG:	HP555_05880

DAO:	Desac_1001

SFU:

Sfum_0452

DAX:	FDQ92_02035

AGV:	OJF2_48710

HMO:

HM1_0988

HCV:	FTV88_2848

» show all

Reference

PMID:28108655

Authors

Malecki J, Aileni VK, Ho AYY, Schwarz J, Moen A, Sorensen V, Nilges BS, Jakobsson ME, Leidel SA, Falnes PO

Title

The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A).

Journal

Nucleic Acids Res 45:4370-4389 (2017)
DOI:10.1093/nar/gkx002

Sequence

[hsa:25895]

LinkDB

DBGET integrated database retrieval system