KEGG   ORTHOLOGY: K22097
Entry
K22097                      KO                                     
Symbol
CXE1
Name
3-O-acetylpapaveroxine carboxylesterase [EC:3.1.1.105]
Pathway
map00950  Isoquinoline alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00946  Noscapine biosynthesis, (S)-reticuline => noscapine
Reaction
R11693  3-O-acetylpapaveroxine acetatehydrolase
R11694  4'-O-desmethyl-3-O-acetylpapaveroxine acetatehydrolase
R12347  3-O-acetylpapaveroxine acetatehydrolase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00950 Isoquinoline alkaloid biosynthesis
    K22097  CXE1; 3-O-acetylpapaveroxine carboxylesterase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.105  3-O-acetylpapaveroxine carboxylesterase
     K22097  CXE1; 3-O-acetylpapaveroxine carboxylesterase
Genes
PSOM: 113322812 113323289
AG: AFB74618(CXE1)
Reference
PMID:22653730
  Authors
Winzer T, Gazda V, He Z, Kaminski F, Kern M, Larson TR, Li Y, Meade F, Teodor R, Vaistij FE, Walker C, Bowser TA, Graham IA
  Title
A Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine.
  Journal
Science 336:1704-8 (2012)
DOI:10.1126/science.1220757
  Sequence
[ag:AFB74618]
Reference
PMID:25485687
  Authors
Dang TT, Chen X, Facchini PJ
  Title
Acetylation serves as a protective group in noscapine biosynthesis in opium poppy.
  Journal
Nat Chem Biol 11:104-6 (2015)
DOI:10.1038/nchembio.1717
LinkDB

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