KEGG   ORTHOLOGY: K22346
Entry
K22346            Tight     KO                                     
Symbol
blaSME
Name
beta-lactamase class A SME [EC:3.5.2.6]
Pathway
map01501  beta-Lactam resistance
Module
M00851  Carbapenem resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    K22346  blaSME; beta-lactamase class A SME
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K22346  blaSME; beta-lactamase class A SME
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.6  beta-lactamase
     K22346  blaSME; beta-lactamase class A SME
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  beta-Lactamase genes
   Class A [MT]
    K22346  blaSME; beta-lactamase class A SME
Antimicrobial resistance: KEGG signatures [br01600.html]
 Signature KOs for antimicrobial resistance
  K22346
Other DBs
COG: COG2367
GO: 0008800
Genes
AG: AAG29813(SME-2) AAS92558(SME-3) CAA82281(SME-1)
Reference
PMID:8092824
  Authors
Naas T, Vandel L, Sougakoff W, Livermore DM, Nordmann P
  Title
Cloning and sequence analysis of the gene for a carbapenem-hydrolyzing class A beta-lactamase, Sme-1, from Serratia marcescens S6.
  Journal
Antimicrob Agents Chemother 38:1262-70 (1994)
DOI:10.1128/AAC.38.6.1262
  Sequence
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