KEGG   ORTHOLOGY: K22465
Entry
K22465                      KO                                     
Symbol
bzaA_B
Name
5-hydroxybenzimidazole synthase [EC:4.1.99.23]
Pathway
map00860  Porphyrin metabolism
map01100  Metabolic pathways
Reaction
R11919  5-amino-1-(5-phospho-beta-D-ribosyl)imidazole formate-lyase (5-hydroxybenzimidazole-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    K22465  bzaA_B; 5-hydroxybenzimidazole synthase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.99  Other carbon-carbon lyases
    4.1.99.23  5-hydroxybenzimidazole synthase
     K22465  bzaA_B; 5-hydroxybenzimidazole synthase
Genes
CACE: CACET_c19200(thiC1) CACET_c19210(thiC2)
CFM: BJL90_15685 BJL90_15690
DOR: Desor_2648 Desor_2649
DAI: Desaci_2510 Desaci_2511
DMI: Desmer_3480 Desmer_3481
DAE: Dtox_1596 Dtox_1597
DKU: Desku_0278 Desku_0279
AACX: DEACI_0774 DEACI_0775
PHOS: ABFY19_03420(thiC) ABFY19_03425(bzaB)
TJR: TherJR_0550 TherJR_0551
DGI: Desgi_1093 Desgi_1094
ELM: ELI_4215 ELI_4216
EMT: CPZ25_011275 CPZ25_011280
ELIM: B2M23_05585 B2M23_05590
AWO: Awo_c14630(thiC2) Awo_c14640(thiC3)
AWI: CHL1_002404(thiC) CHL1_002405(bzaB)
TPZ: Tph_c22270(thiC2) Tph_c22280(thiC3)
MTA: Moth_1722 Moth_1723
MTHO: MOTHE_c17310(thiC2) MOTHE_c17320(thiC3)
MTHZ: MOTHA_c18140(thiC2) MOTHA_c18150(thiC3)
CALK: HUE98_02155(thiC) HUE98_02160(bzaB)
DFO: Dform_00448(thiC) Dform_00449
 » show all
Reference
PMID:26246619
  Authors
Hazra AB, Han AW, Mehta AP, Mok KC, Osadchiy V, Begley TP, Taga ME
  Title
Anaerobic biosynthesis of the lower ligand of vitamin B12.
  Journal
Proc Natl Acad Sci U S A 112:10792-7 (2015)
DOI:10.1073/pnas.1509132112
  Sequence
[elm:ELI_4215 ELI_4216] [mta:Moth_1723 Moth_1722]
LinkDB

DBGET integrated database retrieval system