KEGG   ORTHOLOGY: K22554
Entry
K22554                      KO                                     
Symbol
THEM5
Name
acyl-coenzyme A thioesterase THEM5 [EC:3.1.2.2]
Pathway
map00062  Fatty acid elongation
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    K22554  THEM5; acyl-coenzyme A thioesterase THEM5
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.2  Thioester hydrolases
    3.1.2.2  palmitoyl-CoA hydrolase
     K22554  THEM5; acyl-coenzyme A thioesterase THEM5
Other DBs
RN: R09450
GO: 0047617
Genes
HSA: 284486(THEM5)
PTR: 457304(THEM5)
PPS: 100983203(THEM5)
GGO: 101139248(THEM5)
PON: 100441238(THEM5)
NLE: 100600007(THEM5)
MCC: 100430689(THEM5)
MCF: 102116302(THEM5)
CATY: 105590305(THEM5)
PANU: 101012541(THEM5)
TGE: 112618686(THEM5)
RRO: 104681027(THEM5)
RBB: 108533222(THEM5)
TFN: 117076104(THEM5)
PTEH: 111543664(THEM5)
CJC: 100393740(THEM5)
CSYR: 103263773(THEM5)
MMUR: 105873053(THEM5) 105874499
LCAT: 123635132(THEM5)
OGA: 100964833(THEM5)
MMU: 66198(Them5)
MCAL: 110291753(Them5)
MPAH: 110320928(Them5)
RNO: 361993(Them5)
MCOC: 116094174(Them5)
MUN: 110565676(Them5)
CGE: 100769525(Them5)
MAUA: 101838724(Them5)
PLEU: 114683232(Them5)
AAMP: 119801491(Them5)
NGI: 103730048(Them5)
HGL: 101702565(Them5) 101705063
CPOC: 100720929(Them5)
CCAN: 109696697(Them5)
DORD: 105984936(Them5)
DSP: 122109650(Them5)
NCAR: 124959151
OCU: 100353032(THEM5)
OPI: 101535120(THEM5)
TUP: 102482962(THEM5) 102497766
CFA: 608399(THEM5)
VVP: 112907785(THEM5)
VLG: 121492017(THEM5)
AML: 100481250(THEM5)
UMR: 103667500(THEM5)
UAH: 113246103(THEM5)
UAR: 123787697(THEM5)
ELK: 111161966
LLV: 125098337
MPUF: 101683063(THEM5)
ORO: 101362338(THEM5)
EJU: 114197232(THEM5)
ZCA: 113927953(THEM5)
MLX: 118000362(THEM5)
FCA: 101082506(THEM5)
PYU: 121021086(THEM5)
PBG: 122481186(THEM5)
PTG: 102961219(THEM5)
PPAD: 109257091(THEM5)
AJU: 106980050(THEM5)
BTA: 525765(THEM5)
BOM: 102278986(THEM5)
BIU: 109557012(THEM5)
BBUB: 102392491(THEM5)
CHX: 102187994 102190478(THEM5)
OAS: 101113538 101119950(THEM5)
ODA: 120855859(THEM5) 120867798
CCAD: 122427282(THEM5)
SSC: 100622268(THEM5)
CFR: 102508662(THEM5)
CBAI: 105071702(THEM5)
CDK: 105103231(THEM5)
VPC: 102535879(THEM5)
BACU: 103012688(THEM5)
LVE: 103069390(THEM5)
OOR: 101287201(THEM5)
DLE: 111169788(THEM5)
PCAD: 102987051(THEM5)
PSIU: 116763283(THEM5)
ECB: 100060159(THEM5) 102147639
EPZ: 103547109 103547925(THEM5)
EAI: 106848360(THEM5)
MYB: 102245585(THEM5)
MYD: 102762307(THEM5)
MMYO: 118673637(THEM5)
MLF: 102416889(THEM5)
MNA: 107540779(THEM5)
PKL: 118727292(THEM5)
HAI: 109374382(THEM5)
DRO: 112318347(THEM5)
SHON: 118996800(THEM5)
AJM: 119048125(THEM5)
PDIC: 114489034(THEM5)
PHAS: 123804297(THEM5)
MMF: 118637774(THEM5)
RFQ: 117015089(THEM5)
PALE: 102894686(THEM5)
PGIG: 120585261(THEM5)
PVP: 105303853(THEM5)
RAY: 107500607(THEM5)
MJV: 108396773(THEM5)
TOD: 119235913(THEM5)
SARA: 101547807(THEM5)
LAV: 100672138(THEM5)
DNM: 101440219(THEM5)
MDO: 100019143(THEM5)
GAS: 123247316
SHR: 100923968(THEM5)
PCW: 110216966(THEM5)
OAA: 100091409(THEM5)
 » show all
Reference
  Authors
Zhuravleva E, Gut H, Hynx D, Marcellin D, Bleck CK, Genoud C, Cron P, Keusch JJ, Dummler B, Esposti MD, Hemmings BA
  Title
Acyl coenzyme A thioesterase Them5/Acot15 is involved in cardiolipin remodeling and fatty liver development.
  Journal
Mol Cell Biol 32:2685-97 (2012)
DOI:10.1128/MCB.00312-12
  Sequence
[hsa:284486]
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