KEGG   ORTHOLOGY: K22573
Entry
K22573                      KO                                     
Symbol
AF370
Name
fumagillin biosynthesis polyketide synthase
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00969  Fumagillin biosynthesis, farnesyl-PP => fumagillin
Reaction
R13145  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K22573  AF370; fumagillin biosynthesis polyketide synthase
Other DBs
COG: COG3321 COG0604 COG1028
Genes
AFM: AFUA_8G00370
NFI: NFIA_093910
Reference
  Authors
Lin HC, Tsunematsu Y, Dhingra S, Xu W, Fukutomi M, Chooi YH, Cane DE, Calvo AM, Watanabe K, Tang Y
  Title
Generation of complexity in fungal terpene biosynthesis: discovery of a multifunctional cytochrome P450 in the fumagillin pathway.
  Journal
J Am Chem Soc 136:4426-36 (2014)
DOI:10.1021/ja500881e
  Sequence
LinkDB

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