KEGG   ORTHOLOGY: K22637
Entry
K22637            Tight     KO                                     
Symbol
CYP76AK1
Name
11-hydroxysugiol 20-monooxygenase [EC:1.14.14.67]
Pathway
map00904  Diterpenoid biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R11979  11-hydroxysugiol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (11,20-dihydroxysugiol forming)
R11987  11-hydroxyferruginol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (11,20-dihydroxyferruginol forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00904 Diterpenoid biosynthesis
    K22637  CYP76AK1; 11-hydroxysugiol 20-monooxygenase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K22637  CYP76AK1; 11-hydroxysugiol 20-monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.67  11-hydroxysugiol 20-monooxygenase
     K22637  CYP76AK1; 11-hydroxysugiol 20-monooxygenase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP76 family
   K22637  CYP76AK1; 11-hydroxysugiol 20-monooxygenase
Genes
SMIL: 131020584
AG: AMB36497(CYP76AK1)
Reference
  Authors
Guo J, Ma X, Cai Y, Ma Y, Zhan Z, Zhou YJ, Liu W, Guan M, Yang J, Cui G, Kang L, Yang L, Shen Y, Tang J, Lin H, Ma X, Jin B, Liu Z, Peters RJ, Zhao ZK, Huang L
  Title
Cytochrome P450 promiscuity leads to a bifurcating biosynthetic pathway for tanshinones.
  Journal
New Phytol 210:525-34 (2016)
DOI:10.1111/nph.13790
  Sequence
LinkDB

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