KEGG   ORTHOLOGY: K22726
Entry
K22726                      KO                                     
Symbol
CYP5081B1, HELB2
Name
helvolic acid biosynthesis cytochrome P450 monooxygenase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K22726  CYP5081B1, HELB2; helvolic acid biosynthesis cytochrome P450 monooxygenase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, fungi type
  CYP5081 family
   K22726  CYP5081B1, HELB2; helvolic acid biosynthesis cytochrome P450 monooxygenase
Other DBs
COG: COG2124
Genes
MAJ: MAA_06589
MBRN: 26246764(helB2)
AFM: AFUA_4G14790
NFI: NFIA_101380
Reference
  Authors
Mitsuguchi H, Seshime Y, Fujii I, Shibuya M, Ebizuka Y, Kushiro T
  Title
Biosynthesis of steroidal antibiotic fusidanes: functional analysis of oxidosqualene cyclase and subsequent tailoring enzymes from Aspergillus fumigatus.
  Journal
J Am Chem Soc 131:6402-11 (2009)
DOI:10.1021/ja8095976
  Sequence
Reference
  Authors
Lv JM, Hu D, Gao H, Kushiro T, Awakawa T, Chen GD, Wang CX, Abe I, Yao XS
  Title
Biosynthesis of helvolic acid and identification of an unusual C-4-demethylation process distinct from sterol biosynthesis.
  Journal
Nat Commun 8:1644 (2017)
DOI:10.1038/s41467-017-01813-9
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