ORTHOLOGY: K22732
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Entry
K22732 KO
Symbol
HELE
Name
helvolic acid biosynthesis 3-ketosteroid Delta1-dehydrogenase
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09190 Not Included in Pathway or Brite
09191 Unclassified: metabolism
99988 Secondary metabolism
K22732 HELE; helvolic acid biosynthesis 3-ketosteroid Delta1-dehydrogenase
BRITE hierarchy
Other DBs
COG:
COG1053
Genes
FPOA:
FPOAC1_012942
FPOAC1_013017
FPOAC1_013210
FPOAC1_013267
FPOAC1_013288
FPOAC1_013563
FPOAC1_013585
FPOAC1_013665
FPOAC1_013679
FPOAC1_013838
FPOAC1_013867
NHE:
NECHADRAFT_56510
FFC:
NCS54_00910600
NCS54_01507200
FKR:
NCS57_00928800
NCS57_01378100
NCS57_01491500
MAW:
MAC_07016
MAJ:
MAA_06591
MAA_08883
CFJ:
CFIO01_05280
CLUP:
CLUP02_04661
AFM:
AFUA_4G14850
NFI:
NFIA_101440
APUU:
APUU_51466A
APUU_51467S
ABE:
ARB_05032
TVE:
TRV_01466
NPA:
UCRNP2_396
» show all
Taxonomy
UniProt
Reference
PMID:
19415934
Authors
Mitsuguchi H, Seshime Y, Fujii I, Shibuya M, Ebizuka Y, Kushiro T
Title
Biosynthesis of steroidal antibiotic fusidanes: functional analysis of oxidosqualene cyclase and subsequent tailoring enzymes from Aspergillus fumigatus.
Journal
J Am Chem Soc 131:6402-11 (2009)
DOI:
10.1021/ja8095976
Sequence
[afm:
AFUA_4G14850
]
Reference
PMID:
29158519
Authors
Lv JM, Hu D, Gao H, Kushiro T, Awakawa T, Chen GD, Wang CX, Abe I, Yao XS
Title
Biosynthesis of helvolic acid and identification of an unusual C-4-demethylation process distinct from sterol biosynthesis.
Journal
Nat Commun 8:1644 (2017)
DOI:
10.1038/s41467-017-01813-9
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