KEGG   ORTHOLOGY: K22781
Entry
K22781                      KO                                     
Symbol
US28
Name
HCMV envelope protein US28
Pathway
map04061  Viral protein interaction with cytokine and cytokine receptor
map05163  Human cytomegalovirus infection
Network
nt06124  Chemokine signaling (viruses)
nt06150  Cytokine-cytokine receptor interaction (viruses)
nt06167  Human cytomegalovirus (HCMV)
  Element
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00402  HCMV US28 to GNAQ-PLCB/G-calcineurin signaling pathway
N00404  HCMV US28 to GNAI-AC-PKA signaling pathway
N00406  HCMV US28 to GNA12/13-Rho signaling pathway
N01168  CCL3/7 to HCMV US28 signaling
N01175  CCL2 to HCMV US28 signaling
N01183  CCL5/11/13/26/28 to HCMV US28 signaling
N01212  CCL4 to HCMV US28 signaling
N01262  CX3CL1 to HCMV US28 signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04061 Viral protein interaction with cytokine and cytokine receptor
    K22781  US28; HCMV envelope protein US28
 09160 Human Diseases
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    K22781  US28; HCMV envelope protein US28
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K22781  US28; HCMV envelope protein US28
Viral proteins [BR:ko03200]
 dsDNA viruses
  Human cytomegalovirus (Human herpesvirus 5)
   K22781  US28; HCMV envelope protein US28
Genes
VG: 3077536(US28) 935498(US28)
Reference
  Authors
de Wit RH, Mujic-Delic A, van Senten JR, Fraile-Ramos A, Siderius M, Smit MJ
  Title
Human cytomegalovirus encoded chemokine receptor US28 activates the HIF-1alpha/PKM2 axis in glioblastoma cells.
  Journal
Oncotarget 7:67966-67985 (2016)
DOI:10.18632/oncotarget.11817
  Sequence
[vg:3077536]
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