KEGG   ORTHOLOGY: K22787
Entry
K22787                      KO                                     
Symbol
US3
Name
HCMV membrane glycoprotein US3
Pathway
map05163  Human cytomegalovirus infection
Network
nt06167  Human cytomegalovirus (HCMV)
  Element
N00419  HCMV US3/10 to antigen processing and presentation by MHC class I molecules
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    K22787  US3; HCMV membrane glycoprotein US3
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K22787  US3; HCMV membrane glycoprotein US3
Viral proteins [BR:ko03200]
 dsDNA viruses
  Human cytomegalovirus (Human herpesvirus 5)
   K22787  US3; HCMV membrane glycoprotein US3
Genes
VG: 3077532(US3) 935476(US3)
Reference
PMID:8876135
  Authors
Jones TR, Wiertz EJ, Sun L, Fish KN, Nelson JA, Ploegh HL
  Title
Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains.
  Journal
Proc Natl Acad Sci U S A 93:11327-33 (1996)
DOI:10.1073/pnas.93.21.11327
  Sequence
[vg:3077532]
LinkDB

KEGG   ORTHOLOGY: K21051
Entry
K21051            Tight     KO                                     
Symbol
US10
Name
HCMV unique short US10 glycoprotein
Pathway
map05163  Human cytomegalovirus infection
Network
nt06167  Human cytomegalovirus (HCMV)
  Element
N00419  HCMV US3/10 to antigen processing and presentation by MHC class I molecules
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    K21051  US10; HCMV unique short US10 glycoprotein
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K21051  US10; HCMV unique short US10 glycoprotein
Viral proteins [BR:ko03200]
 dsDNA viruses
  Human cytomegalovirus (Human herpesvirus 5)
   K21051  US10; HCMV unique short US10 glycoprotein
Genes
VG: 3077551(US10)
Reference
  Authors
Furman MH, Dey N, Tortorella D, Ploegh HL
  Title
The human cytomegalovirus US10 gene product delays trafficking of major histocompatibility complex class I molecules.
  Journal
J Virol 76:11753-6 (2002)
DOI:10.1128/JVI.76.22.11753-11756.2002
  Sequence
[vg:3077551]
Reference
  Authors
Park B, Spooner E, Houser BL, Strominger JL, Ploegh HL
  Title
The HCMV membrane glycoprotein US10 selectively targets HLA-G for degradation.
  Journal
J Exp Med 207:2033-41 (2010)
DOI:10.1084/jem.20091793
  Sequence
[vg:3077551]
LinkDB

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