KEGG ORTHOLOGY: K22823

ORTHOLOGY: K22823

Entry

K22823                      KO

Symbol

NSMCE3, NSE3

Name

non-structural maintenance of chromosomes element 3

Disease

H00094

Immunodeficiency associated with DNA repair defects

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K22823  NSMCE3, NSE3; non-structural maintenance of chromosomes element 3
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    SMC5-SMC6 complex
     K22823  NSMCE3, NSE3; non-structural maintenance of chromosomes element 3

Genes

HSA:	56160(NSMCE3)

PTR:	745658(NSMCE3)

PPS:	100987855(NSMCE3)

GGO:	101147087(NSMCE3)

PON:	100445892(NSMCE3)

PPYG:

129014031(NSMCE3)

NLE:	100590611(NSMCE3)

HMH:	116482448(NSMCE3)

SSYN:

129482539(NSMCE3)

MCC:	712714(NSMCE3)

MCF:	102137142(NSMCE3)

MTHB:

126960117

MNI:	105497509(NSMCE3)

CSAB:

103245949(NSMCE3)

CATY:

105573510 105597526(NDNL2)

PANU:

100998282(NSMCE3)

TGE:	112627923(NSMCE3)

MLEU:

105550766(NDNL2)

RRO:	104670269(NSMCE3)

RBB:	108526797(NSMCE3)

TFN:	117070960(NSMCE3)

PTEH:

111523251(NSMCE3)

CANG:

105516905(NDNL2)

CJC:	100394848(NSMCE3) 100404404

SBQ:	101046278(NDNL2)

CIMI:

108296359(NSMCE3)

ANAN:

105730949(NSMCE3)

CSYR:

103250853(NSMCE3)

MMUR:

105871298(NSMCE3)

LCAT:

123644693(NSMCE3)

PCOQ:

105808943(NDNL2)

OGA:	105888113(NSMCE3)

MMU:	66647(Nsmce3) 75555(Nscme3l)

MCAL:

110285389 110298492(Nsmce3)

MPAH:

110325277(Nsmce3) 110326333

RNO:	102551929(Mageb10) 309259(Nsmce3)

MCOC:

116102341(Nsmce3) 116103397

ANU:	117693977(Nsmce3) 117712629

ASYL:

127667962(Nsmce3) 127692323

MUN:	110549330 110553645(Nsmce3)

CGE:	100763256 100764696 100772988

MAUA:

101824485(Nsmce3) 101837550

PROB:

127228700 127238003(Nsmce3)

PLEU:

114695492(Nsmce3) 114709155

MORG:

121447857(Nsmce3) 121454072

MFOT:

126498864 126505933

AAMP:

119802729(Nsmce3) 119828044

NGI:	103724999 103748077(Nsmce3)

HGL:	101725921(Nsmce3)

CPOC:

100718703(Nsmce3)

CCAN:

109695591(Nsmce3)

DORD:

105982515(Ndnl2)

DSP:	122110614 122123983(Nsmce3)

DMER:

138842018(Nsmce3)

PLOP:

125338611(Nsmce3)

NCAR:

124977356

MMMA:

107148481(Nsmce3)

ITI:	101977980(Nsmce3)

OCU:

100345871

OPI:

101532192

OCZ:	121148950(NSMCE3)

TUP:	106733737(NSMCE3)

GVR:	103605313(NDNL2)

VVP:	112922401(NSMCE3)

VLG:	121489443(NSMCE3) 121489444

NPO:	129510481(NSMCE3)

AML:	105241346(NSMCE3)

UMR:	103659973(NSMCE3)

UAH:	113263616(NSMCE3)

UAR:	123790770(NSMCE3)

ELK:

111152596

LLV:

125104575

MPUF:

101693582(NDNL2)

MNP:	131999109(NSMCE3)

MLK:	131835705(NSMCE3)

NVS:	122894247(NSMCE3)

ORO:	101363937(NDNL2)

EJU:	114223801(NSMCE3)

ZCA:	113910095(NSMCE3)

MLX:	118022978(NSMCE3)

NSU:	110572249(NSMCE3)

LWW:	102731130(NSMCE3)

FCA:	102901247(NSMCE3)

PYU:	121042514(NSMCE3)

PCOO:

112855436(NSMCE3)

PBG:	122468325(NSMCE3)

PVIV:

125168740(NSMCE3)

LRUF:

124517359

LGF:	123582593(NSMCE3)

AJU:

106983745

PTG:	102951740(NSMCE3)

PPAD:

109273322(NSMCE3)

PUC:

125910226

PLEZ:

122221705(NSMCE3)

HHV:	120225977(NSMCE3) 120227677

BTA:	617494(NSMCE3)

BOM:	102274617 102276432(NSMCE3)

BIU:	109565942 109575600(NSMCE3)

BBUB:

102404232(NSMCE3)

BBIS:

104989884(NDNL2)

CHX:	106503364(NSMCE3)

OAS:	101119676(NSMCE3)

BTAX:

128066648(NSMCE3)

CSUM:

138095384(NSMCE3)

ODA:	120875528(NSMCE3)

CCAD:

122455220(NSMCE3)

MREE:

136147053(NSMCE3)

OVR:	110124716(NSMCE3)

MBEZ:

129550384(NSMCE3)

SSC:	100620354(NSMCE3)

CFR:	102517790(NSMCE3)

CBAI:

105075142(NDNL2)

CDK:	105093464(NSMCE3)

VPC:	102532136(NSMCE3)

BACU:

103008001(NSMCE3)

BMUS:

118890495(NSMCE3)

LVE:	103088822(NDNL2)

OOR:	101270400(NSMCE3)

LALB:

132532355(NSMCE3)

GMF:	115864563(NSMCE3)

DDP:	132420656(NSMCE3)

DLE:	111164675(NSMCE3)

PCAD:

102983439(NSMCE3)

PSIU:

116749910(NSMCE3)

PPHC:

136119102(NSMCE3)

NASI:

112398331(NSMCE3)

ECB:	106782075(NSMCE3)

EPZ:	103567015(NSMCE3)

EAI:	106834043(NSMCE3)

MYB:	102244638(NSMCE3)

MYD:	102763338(NSMCE3)

MMYO:

118679195(NSMCE3)

MLF:	102423057(NSMCE3)

MDT:	132223015(NSMCE3)

MYUM:

138998273(NSMCE3)

PKL:	118717026(NSMCE3)

EFUS:

103303130(NSMCE3)

MNA:	107527521(NSMCE3)

DRO:	112306009(NSMCE3)

SHON:

118992039(NSMCE3)

AJM:	119049777(NSMCE3)

PDIC:

114488555(NSMCE3)

PHAS:

123809596(NSMCE3)

MMF:	118640839(NSMCE3)

PPAM:

129061234(NSMCE3)

HAI:	109372175(NSMCE3)

RFQ:	117018960(NSMCE3)

PALE:

102891587(NSMCE3)

PGIG:

120595312(NSMCE3) 120596595

PVP:

105310601

RAY:	107515773(NSMCE3)

MJV:	108389645(NSMCE3)

TOD:	119244349(NSMCE3)

SARA:

105943326(NDNL2)

SFUM:

130032850(NSMCE3)

SETR:

126021838(NSMCE3)

LAV:	100676270(NSMCE3)

TMU:

105756066

ETF:	105978326(NSMCE3)

DNM:	101442823 105745587(NSMCE3)

MDO:

100617402

GAS:	123250702 123254001

SHR:

AFZ:

PCW:

TVP:

PBRV:

OAA:

TACU:

GGA:	100125831(NSMCE3)

PCOC:

NMEL:

ACYG:

CATA:

LSR:

SCAN:

PMOA:

OTC:

PRUF:

ATRC:

GFR:

FAB:

OMA:

PHI:

PMAJ:

CCAE:

CCW:

CBRC:

ZAB:

ZLE:

SVG:

CCIC:

FPG:

FCH:

SHAB:

ACHC:

HLE:

HHAR:

EGZ:

CBOR:

CBOY:

CLV:

CNIC:

PGUU:

CUCA:

ACAR:

CRID:

LMIC:

AAM:

AROW:

NPD:

DNE:

ASN:

AMJ:

PSS:	102458302 102459787

CIZ:

142002882

CMY:	102932998 102942038

CCAY:

125631811

DCC:	119847047 119849134

CPIC:

101938275

TST:

117869200

CABI:

116823934(TRO) 116840161

MRV:

ACS:

ASAO:

PVT:

SUND:

PBI:

PMUR:

CTIG:

TSR:

PGUT:

PCAE:

APRI:

PTEX:

NSS:

VKO:

PMUA:

PRAF:

ZVI:

HCG:

GJA:

STOW:

EMC:

XLA:	108699990 108718079

XTR:	549684(nsmce3)

NPR:

RTEM:

ACAT:

BBUF:

BGAR:

DTC:

PWL:

MUO:

GSH:

DRE:	386658(ndnl2)

SRX:	107714263 107736943

SANH:

SGH:

CCAR:

CAUA:

CGIB:

PTET:

122328532(ndnl2)

LROH:

127154647(ndnl2)

GRF:	141291499(ndnl2)

OMC:	131532712(ndnl2)

PPRM:

120479056(ndnl2)

RKG:	130079543(ndnl2)

MAMB:

125260043(ndnl2)

CIDE:

127505429

CERY:

137009059(ndnl2)

MASI:

127419669

TROS:

130549563(ndnl2)

TDW:	130409733(ndnl2)

MANU:

129430720(ndnl2)

PDAB:

135775881(ndnl2)

IPU:	108276355(ndnl2)

IFU:	128619124(ndnl2)

SMEO:

124398968(ndnl2)

TFD:	113637434(ndnl2)

TVC:	132862593(ndnl2)

CGAR:

128510059(ndnl2)

NGRA:

132896328(ndnl2)

TRN:	134333449(ndnl2)

AMEX:

103046921(ndnl2)

CMAO:

118822969(ndnl2)

EEE:

113572337

CHAR:

105900181(ndnl2)

SPIL:

134087493(ndnl2)

ASAD:

121713184(ndnl2)

TRU:	105419445 115246480

TFS:	130530736(ndnl2)

TNG:	GSTEN00013117G001

LCO:

104933589

NCC:

104951562

TBEN:

117483526(ndnl2)

CGOB:

115004812 115010552

PGEO:

117449627(ndnl2)

GACU:

117535213(ndnl2)

EMAC:

134862548(ndnl2)

ELY:	117258540(ndnl2)

EFO:	125892275(ndnl2)

PLEP:

121937944(ndnl2)

SLUC:

116060431(ndnl2)

ESP:

116679206

PFLV:

114559136

PPUG:

119222238(ndnl2)

AFB:	129099239(ndnl2)

CLUM:

117733385(ndnl2)

PSWI:

130199584(ndnl2)

CANA:

137800033(ndnl2)

CVE:	137872305(ndnl2)

MSAM:

119905025(ndnl2)

CUD:	121517407(ndnl2)

SPUL:

138589250(ndnl2)

LMIX:

132990207(ndnl2)

HTC:	141799388(ndnl2)

ALAT:

119022487(ndnl2)

ASTR:

137607131(ndnl2)

MZE:

101468845

ONL:

100699832

OAU:	116311861(ndnl2)

OLA:

101154928

OML:	112140844(ndnl2)

CSAI:

133456796(ndnl2)

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122831034(ndnl2)

PPRL:

129356247 129377139

CVG:

107096781

CTUL:

119799495(ndnl2)

GMU:	124876081(ndnl2)

NFU:

107390537

KMR:	108249712(ndnl2)

ALIM:

106512590 106535230

NWH:	119416863(ndnl2)

AOCE:

111583553(ndnl2)

EJA:	138199641(ndnl2)

BFRE:

138637287(ndnl2)

MCEP:

125010955(ndnl2)

CSEM:

103384531

POV:

109641419

SSEN:

122777854(ndnl2)

SSOE:

131468545(ndnl2)

HHIP:

117764232 117764233

HSP:	118111587(ndnl2)

PPLT:

128441975(ndnl2)

SMAU:

118316477(ndnl2)

LCF:	108873289(ndnl2)

SDU:

111237634

SLAL:

111673372

XGL:	120804229(ndnl2)

HCQ:

109519818

SSCV:

125968638(ndnl2)

SBIA:

133506448(ndnl2)

PEE:	133404430(ndnl2)

PTAO:

133477505(ndnl2)

BPEC:

110169982

ENY:	140362500(ndnl2)

MALB:

109965244

BSPL:

114858812(ndnl2)

SJO:	128358021(ndnl2)

SSCO:

133976849(ndnl2)

GMH:

115540302

SASA:

106593143

STRU:

115168754

OTW:	112222426(ndnl2)

OMY:	110492728(ndnl2)

OGO:	124045385(ndnl2)

ONE:

115101922

OKI:

109886201

OKE:	118359517 127916912(ndnl2)

OMM:	135527661(ndnl2)

OCLA:

139367807

SNH:	120060811(ndnl2)

SFON:

129861381(ndnl2)

CCLU:

121546604(ndnl2)

ELS:

105013509

OEP:	134019508(ndnl2)

SFM:

108918447

PKI:

111856968

AANG:

118210757(ndnl2)

AROT:

135237763(ndnl2)

CCOG:

133109652 133110455

LOC:

102684185

PSPA:

121305403(ndnl2)

ARUT:

117401690(ndnl2)

PSEX:

120542689(ndnl2)

LCM:

102350471

CMK:	103176271(ndnl2)

SCAU:

119955744(ndnl2)

HAKA:

PMRN:

LRJ:

BFO:

BBEL:

CIN:

SPU:

LPIC:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

PFLL:

DME:	Dmel_CG10059(MAGE)

DER:

6553195

DSE:

6614212

DSI:	Dsimw501_GD19499(Dsim_GD19499)

DYA:	Dyak_GE25809 Dyak_GE25812(Dyak_MAGE)

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI24515

DAZ:

108609140

DNV:

108659264

DHE:

111603634

DVI:	6631229(MAGE)

CCAT:

BOD:

BDR:

AOQ:

ALUD:

TDA:	119681454 119682783

MDE:

101896136

SCAC:

106083585

LCQ:

111688402

LSQ:	119612433 119614800

CVJ:	135949051(MAGE)

GFS:

ECOE:

CLON:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:

AALB:

109405395 109430080 109430752 109431063

ASUA:

134225884

CQU:	CpipJ_CPIJ003760

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

TLN:

HST:

DQU:

CFO:

FEX:

LHU:	105675792(MAGE)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LBD:

MDL:

CGLO:

CTYP:

FAS:	105270218 105270223

DAM:	107044904 107044909

AGIF:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

SOY:

AGRG:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_200986

BANY:

MJU:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PGW:

LGLY:

CSTB:

CFUM:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106677501(MAGE)

NLU:

111058592

LDA:

142328815

MQU:	128994448 128995370

PHU:	Phum_PHUM126170

FOC:

113202655

TPAL:

117641046 117648319

ZNE:	110826871 110832519

CSEC:

111867760

PAME:

138691105(MAGE)

BROR:

134534751

IEL:

124154573

HAMR:

139687671(MAGE)

DPX:	DAPPUDRAFT_211258

AFRA:

136035505

PVM:	113829286 113829759

PJA:

122261692

PMOO:

119587749

HAME:

121873704

PCLA:

123758748(MAGE)

PTRU:

ESN:

MRJ:

PORN:

HAZT:

EAF:

LSM:

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

GOE:

TUT:

DPTE:

DFR:

CVS:	136968414(MAGE)

ABRU:

129972923

UDV:

129217673

LPOL:

106475002

LGI:	LOTGIDRAFT_56299

PVUL:

PCAN:

LSAX:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:	106156462 106169463

LLON:

135491274

NVE:

5520600

EPA:	110236115 110250224

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_58431

AQU:

105316664

SCE:	YDR288W(NSE3)

SEUB:

DI49_0466

SPAO:

SPAR_D04800

AGO:	AGOS_AAL120C

ERC:

Ecym_4745

KLA:	KLLA0_D08734g

KMX:	KLMA_20724

LTH:	KLTH0G06578g

VPO:	Kpol_364p7

ZRO:	ZYRO0G16522g

CGR:	2888501(GVI51_H00869)

NCS:	NCAS_0F02470(NCAS0F02470)

NDI:	NDAI_0C03950(NDAI0C03950)

TPF:	TPHA_0E02130(TPHA0E02130)

TBL:	TBLA_0C03200(TBLA0C03200)

TGB:	HG536_0E03450

TDL:	TDEL_0E03340(TDEL0E03340)

KAF:	KAFR_0E01440(KAFR0E01440)

KNG:	KNAG_0F03350(KNAG0F03350)

ZMK:	HG535_0A04460

DHA:	DEHA2G17534g

PIC:	PICST_58773

PGU:	PGUG_04566

SPAA:

SPAPADRAFT_58693

LEL:	PVL30_004280

LBG:	92210390(LODBEIA_P51940)

CAL:	CAALFM_C403170WA(CaO19.2673)

CTP:	CTRG_00486

COT:	CORT_0E04040

CDU:	CD36_43020

CTEN:

18249012(PSN45_000172)

CLU:	CLUG_00806

CLUS:

BBRX:

ACAN:

Reference

PMID:18086888

Authors

Taylor EM, Copsey AC, Hudson JJ, Vidot S, Lehmann AR

Title

Identification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complex.

Journal

Mol Cell Biol 28:1197-206 (2008)
DOI:10.1128/MCB.00767-07

Sequence

[hsa:56160]

Reference

PMID:15752197

Authors

Hu B, Liao C, Millson SH, Mollapour M, Prodromou C, Pearl LH, Piper PW, Panaretou B

Title

Qri2/Nse4, a component of the essential Smc5/6 DNA repair complex.

Journal

Mol Microbiol 55:1735-50 (2005)
DOI:10.1111/j.1365-2958.2005.04531.x

Sequence

[sce:YDR288W]

LinkDB

DBGET integrated database retrieval system