KEGG ORTHOLOGY: K23012

ORTHOLOGY: K23012

Entry

K23012                      KO

Symbol

TYSND1

Name

peroxisomal leader peptide-processing protease [EC:3.4.21.-]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K23012  TYSND1; peroxisomal leader peptide-processing protease
Peptidases and inhibitors [BR:ko01002]
Serine peptidases
  Family S1: chymotrypsin family
   K23012  TYSND1; peroxisomal leader peptide-processing protease

Genes

HSA:	219743(TYSND1)

PTR:	746962(TYSND1)

PPS:	100972363(TYSND1)

GGO:	101134740(TYSND1)

PON:	100456632(TYSND1)

PPYG:

129006818(TYSND1)

NLE:	100590702(TYSND1)

HMH:	116458902(TYSND1)

SSYN:

129480597(TYSND1)

MCC:	100425207(TYSND1)

MCF:	102135762(TYSND1)

MTHB:

126962508

MNI:	105466080(TYSND1)

CSAB:

103216061(TYSND1)

CATY:

105597271(TYSND1)

PANU:

101019537(TYSND1)

TGE:	112630957(TYSND1)

RRO:	104661976(TYSND1)

RBB:	108530346(TYSND1)

TFN:	117082574(TYSND1)

PTEH:

111537901(TYSND1)

CANG:

105501376(TYSND1)

CJC:	100414919(TYSND1)

SBQ:	101043865(TYSND1)

CIMI:

108318109(TYSND1)

ANAN:

105722657(TYSND1)

CSYR:

103249918(TYSND1)

MMUR:

105870199(TYSND1)

LCAT:

123650442(TYSND1)

PCOQ:

105821882(TYSND1)

OGA:	100959389(TYSND1)

MMU:	71767(Tysnd1)

MCAL:

110303858(Tysnd1)

MPAH:

110326476(Tysnd1)

RNO:	365571(Tysnd1)

MCOC:

116074971(Tysnd1)

ANU:	117724802(Tysnd1)

ASYL:

127669690(Tysnd1)

MUN:	110555913(Tysnd1)

CGE:	100769469(Tysnd1)

MAUA:

101841448(Tysnd1)

PROB:

127224006(Tysnd1)

PLEU:

114704752(Tysnd1)

MORG:

121451107(Tysnd1)

MFOT:

126501226

AAMP:

119823434(Tysnd1)

NGI:	108489999(Tysnd1)

HGL:	101712356(Tysnd1)

CPOC:

100715057(Tysnd1)

CCAN:

109685263(Tysnd1)

DORD:

105986331(Tysnd1)

DSP:	122122334(Tysnd1)

PLOP:

125346412(Tysnd1)

NCAR:

124985479

MMMA:

107154818(Tysnd1)

ITI:	101955875(Tysnd1)

OCU:

100340430

OPI:	101518934(TYSND1)

TUP:	102490588(TYSND1)

CFA:	100687512(TYSND1)

CLUD:

112651422(TYSND1)

VVP:	112927722(TYSND1)

VLG:	121487713(TYSND1)

NPO:	129509482(TYSND1)

AML:	100482317(TYSND1)

UMR:	103668011(TYSND1)

UAH:	113259136(TYSND1)

UAR:	123782967(TYSND1)

ELK:

111144901

MPUF:

101692775(TYSND1)

MNP:	132016380(TYSND1)

MLK:	131828874(TYSND1)

NVS:	122900752(TYSND1)

ORO:	101371531(TYSND1)

EJU:	114214159(TYSND1)

ZCA:	113923805(TYSND1)

MLX:	118018303 118019034

NSU:	110589288(TYSND1)

LWW:	102732845(TYSND1)

FCA:	101098894(TYSND1)

PYU:	121036735(TYSND1)

PCOO:

112854393(TYSND1)

PBG:	122492844(TYSND1)

PVIV:

125148262(TYSND1)

LRUF:

124506867

LGF:	123576623(TYSND1)

AJU:

106967194

PPAD:

109264361(TYSND1)

PUC:

125932704

PLEZ:

122202355(TYSND1)

HHV:	120232521(TYSND1)

BTA:	101903772(TYSND1)

BOM:	102271183(TYSND1)

BIU:	109553750(TYSND1)

BBUB:

102406361(TYSND1)

CHX:	102182668(TYSND1)

OAS:	101109145(TYSND1)

BTAX:

128047919(TYSND1)

CSUM:

138087429(TYSND1)

ODA:	120865174(TYSND1)

CCAD:

122446457(TYSND1)

MREE:

136159827(TYSND1)

OVR:	110127257(TYSND1)

MBEZ:

129555757(TYSND1)

SSC:	100157601(TYSND1)

CFR:	102519792(TYSND1)

CBAI:

105066385(TYSND1)

CDK:	105099875(TYSND1)

VPC:	102529600(TYSND1)

BACU:

103017763(TYSND1)

BMUS:

118882997(TYSND1)

LVE:	103083211(TYSND1)

OOR:	101269583(TYSND1)

LALB:

132507312(TYSND1)

DLE:	111183466(TYSND1)

PCAD:

102982743(TYSND1)

PSIU:

116741708(TYSND1)

NASI:

112413542(TYSND1)

ECB:	100072712(TYSND1)

EPZ:	103549390(TYSND1)

EAI:	106845027(TYSND1)

MYB:	102248307(TYSND1)

MYD:	102764723(TYSND1)

MMYO:

118670096(TYSND1)

MLF:	102443236(TYSND1)

MDT:	132214873(TYSND1)

MYUM:

139021985(TYSND1)

PKL:	118719152(TYSND1)

EFUS:

103289591(TYSND1)

MNA:	107526064(TYSND1)

DRO:	112305495(TYSND1)

SHON:

118975336(TYSND1)

AJM:	119038150(TYSND1)

PDIC:

114496701(TYSND1)

PHAS:

123820907(TYSND1)

MMF:	118632604(TYSND1)

PPAM:

129069919(TYSND1)

HAI:	109372186(TYSND1)

RFQ:	117036240(TYSND1)

PALE:

102892523(TYSND1)

PGIG:

120609481(TYSND1)

PVP:	105300116(TYSND1)

RAY:	107498210(TYSND1)

MJV:	108387862(TYSND1)

TOD:	119233345(TYSND1)

SFUM:

130022728(TYSND1)

SETR:

126033525(TYSND1)

LAV:	100670229(TYSND1)

TMU:

101356754

ETF:	101661909(TYSND1)

DNM:	101446182(TYSND1)

MDO:	100023103(TYSND1)

GAS:	123236509(TYSND1)

SHR:	100917713(TYSND1)

AFZ:

127552084

PCW:	110200087(TYSND1)

TVP:	118859147(TYSND1)

PBRV:

138148642(TYSND1)

OAA:	114810104(TYSND1)

TACU:

119925292(TYSND1)

GGA:	769373(TYSND1)

PCOC:

116235043(TYSND1)

MGP:	104911935(TYSND1)

CJO:	107315695(TYSND1)

TPAI:

128077696(TYSND1)

LMUT:

125693612(TYSND1)

NMEL:

110400002(TYSND1)

APLA:

113844007(TYSND1)

ACYG:

125183439(TYSND1)

CATA:

118244245(TYSND1)

AFUL:

116491264(TYSND1)

TGU:	115495732(TYSND1)

LSR:	110477772(TYSND1)

SCAN:

103823738(TYSND1)

PMOA:

120501063(TYSND1)

OTC:	121336178(TYSND1)

PRUF:

121353882(TYSND1)

ATRC:

139595385(TYSND1)

FAB:	101811333(TYSND1)

OMA:	130255192(TYSND1)

PHI:	102099917(TYSND1)

PMAJ:

107206552(TYSND1)

CCW:	120410245(TYSND1)

ACOE:

138112205(TYSND1)

ETL:	114066300 114071306(TYSND1)

ZLE:	135449524(TYSND1)

SVG:	106856698(TYSND1)

MMEA:

130582410(TYSND1)

HRT:	120755778(TYSND1)

SATI:

136364560(TYSND1)

CCIC:

134046356(TYSND1)

SHAB:

115608599(TYSND1)

TALA:

116961408(TYSND1)

ACHC:

115348374(TYSND1)

AGEN:

126043110

HHAR:

128147505(TYSND1)

GCL:

127017687

LDI:	104349608(TYSND1)

PPUS:

135176205(TYSND1)

NNI:	104013559(TYSND1)

CBOY:

140655490(TYSND1)

CLV:	102087548 102090444

CUCA:

104064302(TYSND1)

RTD:	128911613(TYSND1)

CRID:

134517261(TYSND1)

ASN:	102369395(TYSND1)

AMJ:	102568232(TYSND1)

CPOO:

109312558(TYSND1)

GGN:	109290909(TYSND1)

PSS:	102461721(TYSND1)

CMY:	102937937(TYSND1)

CCAY:

125640466(TYSND1)

DCC:	119858361(TYSND1)

CPIC:

101942859(TYSND1)

TST:	117880769(TYSND1)

CABI:

116826520(TYSND1)

MRV:	120409420(TYSND1)

ACS:	100566606(tysnd1)

ASAO:

132771155(TYSND1)

PVT:	110073689(TYSND1)

SUND:

121927286(TYSND1)

PBI:	103049464(TYSND1)

PMUR:

107296301(TYSND1)

CTIG:

120299650(TYSND1)

PGUT:

117670667(TYSND1)

APRI:

131201140(TYSND1)

PTEX:

113444680(TYSND1)

NSS:	113421025(TYSND1)

VKO:	123018437(TYSND1)

PMUA:

114597244(TYSND1)

PRAF:

128413959(TYSND1)

ZVI:	118096221(TYSND1)

HCG:	128348953(TYSND1)

GJA:	107119732(TYSND1)

STOW:

125438574(TYSND1)

EMC:	129331715(TYSND1)

XLA:	108696234(tysnd1.L)

XTR:	100379910(tysnd1)

NPR:	108792202(TYSND1)

RTEM:

120947198(TYSND1)

BBUF:

121004422(TYSND1)

BGAR:

122941535(TYSND1)

PWL:	138300703(TYSND1)

MUO:	115470380(TYSND1)

GSH:	117360133(TYSND1)

DRE:	561667(tysnd1)

SRX:	107708039 107716300

SANH:

107673878

SGH:

107578377

CCAR:

109066114 109100810

CAUA:

113074863 113096128 113112547

CGIB:

127970527 128026133

PTET:

122356580(tysnd1)

LROH:

127175717(tysnd1)

OMC:	131552439(tysnd1)

PPRM:

120479312(tysnd1)

RKG:	130077604(tysnd1)

MAMB:

125277016(tysnd1)

CIDE:

127524605

CERY:

137020102(tysnd1)

MASI:

127412232

TROS:

130559164(tysnd1)

TDW:	130431657(tysnd1)

MANU:

129415997(tysnd1)

PDAB:

135786951(tysnd1)

IPU:

108263847

IFU:	128605651(tysnd1)

PHYP:

113538291(tysnd1)

SMEO:

124399887(tysnd1)

TFD:	113639916(tysnd1)

TVC:	132847330(tysnd1)

CGAR:

128528440(tysnd1)

NGRA:

132888674(tysnd1)

TRN:	134314580(tysnd1)

AMEX:

103024644(tysnd1)

CMAO:

118810439(tysnd1)

EEE:	113580937(tysnd1)

CHAR:

105909529(tysnd1)

SPIL:

134064493(tysnd1)

TRU:	101078752(tysnd1)

TFS:	130534054(tysnd1)

TNG:	GSTEN00016438G001

LCO:	104930545(tysnd1)

NCC:	104956657(tysnd1)

TBEN:

117499586(tysnd1)

CGOB:

115020055(tysnd1)

PGEO:

117459783(tysnd1)

GACU:

117538179(tysnd1)

EMAC:

134858373(tysnd1)

ELY:	117247983(tysnd1)

EFO:	125903115(tysnd1)

PLEP:

121954780(tysnd1)

SLUC:

116054631(tysnd1)

ECRA:

117960612(tysnd1)

ESP:	116704984(tysnd1)

PFLV:

114572128(tysnd1)

GAT:	120821115(tysnd1)

PPUG:

119213993(tysnd1)

AFB:	129092452(tysnd1)

CLUM:

117744522(tysnd1)

PSWI:

130207000(tysnd1)

CANA:

137779849(tysnd1)

CVE:	137880375(tysnd1)

MSAM:

119917496(tysnd1)

SCHU:

122884736(tysnd1)

CUD:	121510749(tysnd1)

SPUL:

138588903(tysnd1)

LMIX:

132975363(tysnd1)

ALAT:

119034135(tysnd1)

ASTR:

137603765(tysnd1)

MZE:	101484130(tysnd1)

ONL:	100691556(tysnd1)

OAU:	116316644(tysnd1)

OLA:	101175429(tysnd1)

OML:	112161412(tysnd1)

CSAI:

133463439(tysnd1)

XMA:	102229333(tysnd1)

XCO:	114137990(tysnd1)

XHE:	116713674(tysnd1)

PRET:

103476837(tysnd1)

PFOR:

103133491(tysnd1)

PLAI:

106944654(tysnd1)

PMEI:

106917940(tysnd1)

GAF:	122843012(tysnd1)

PPRL:

129359873(tysnd1)

CVG:	107091033(tysnd1)

CTUL:

119788531(tysnd1)

GMU:	124859180(tysnd1)

NFU:	107396325(tysnd1)

KMR:	108243706(tysnd1)

ALIM:

106515348(tysnd1)

NWH:	119419393(tysnd1)

AOCE:

111573888(tysnd1)

EJA:	138195305(tysnd1)

BFRE:

138617595(tysnd1)

MCEP:

125018733(tysnd1)

CSEM:

103387238(tysnd1)

POV:	109629881(tysnd1)

SSEN:

122781880(tysnd1)

SSOE:

131474117(tysnd1)

HHIP:

117775800(tysnd1)

HSP:	118118569(tysnd1)

PPLT:

128453443(tysnd1)

SMAU:

118283423(tysnd1)

LCF:

108897268

SDU:	111235309(tysnd1)

SLAL:

111670033(tysnd1)

XGL:	120796883(tysnd1)

HCQ:	109512381(tysnd1)

SSCV:

125978073(tysnd1)

SBIA:

133509850(tysnd1)

PEE:	133410010(tysnd1)

PTAO:

133485538(tysnd1)

BPEC:

110173619(tysnd1)

ENY:	140351321(tysnd1)

MALB:

109961869(tysnd1)

BSPL:

114870778(tysnd1)

SJO:	128372755(tysnd1)

SSCO:

133991914(tysnd1)

GMH:	115559806(tysnd1)

SASA:

106577214(tysnd1)

STRU:

115193606(tysnd1)

OTW:	112247199(tysnd1)

OMY:	110530458(tysnd1)

OGO:	124040723(tysnd1)

ONE:	115134980(tysnd1)

OKI:	109890047(tysnd1)

OKE:	118369844(tysnd1)

OMM:	135511158(tysnd1)

OCLA:

139413063

SALP:

111951825(tysnd1)

SNH:	120017743(tysnd1)

CCLU:

121553694(tysnd1)

ELS:	105021426(tysnd1)

OEP:	134022133(tysnd1)

SFM:	108925799(tysnd1)

PKI:	111858900(tysnd1)

AANG:

118218070(tysnd1)

AROT:

135245321(tysnd1)

CCOG:

133118183(tysnd1)

LOC:	102695523(tysnd1)

PSPA:

121322050(tysnd1)

ARUT:

117415178(tysnd1) 117417865

PSEX:

120541248(tysnd1)

LCM:	102366671(TYSND1)

CMK:	103181318(tysnd1)

RTP:	109922713(tysnd1)

CPLA:

122541919(tysnd1)

HOC:	132834937(tysnd1)

LERI:

129712952(tysnd1)

PMRN:

116938803(TYSND1)

LRJ:	133345867(TYSND1)

BFO:

118410008

CIN:

108949513

SCLV:

120341458

SPU:	100888502 115927744

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

SKO:

PFLL:

DME:	Dmel_CG3589(CG3589)

DER:

6548406

DSE:

6618881

DSI:	Dsimw501_GD11897(Dsim_GD11897)

DYA:	Dyak_GE14443

DAN:

DSR:

DPO:

DPE:

DMN:	108159157 117192581

DWI:

6640533

DGR:

6561279

DMO:	Dmoj_GI20027

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:	105234253(Tysd1)

RZE:

AOQ:

ALUD:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

CVJ:

GFS:

ECOE:

CLON:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ003973

CPII:

CBRI:

BCOO:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

CCAL:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

TLN:

HST:

DQU:

CFO:

FEX:

PMEC:

LHU:

PGC:

OBO:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

DSM:

NPT:	124218986(Prosalpha5)

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

ESIM:

ATD:

CSET:

HAXR:

AGB:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_202909

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:	105390980 125488444

PGW:

LGLY:

CSTB:

CCRN:

API:

DNX:

AGS:

RMD:

BTAB:

DCI:	103518282 103518283

CLEC:

HHAL:

HVI:

MQU:

FOC:

ZNE:

CSEC:

PAME:

BROR:

HAMR:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

MNZ:

MRJ:

PORN:

HRO:	HELRODRAFT_159887

LGI:	LOTGIDRAFT_172074

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:	111099700 111120262

OED:

MYI:

PMAX:

AIRR:

RPHI:

MAEA:

OBI:

LJP:

LAK:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

TAD:	TRIADDRAFT_59478

AQU:

100641600

ATH:	AT1G28320(DEG15)

ALY:

9329584

CRB:

17899243

CSAT:

104741440 104757172

EUS:	EUTSA_v10006942mg EUTSA_v10007180mg

BRP:

103838965

BNA:	106422077 106448550

BOE:

RSZ:

THJ:

CPAP:

CIT:

CIC:	CICLE_v10014582mg

PVY:

MINC:

TCC:

GRA:

GHI:	107900139 107911940

GAB:

HSYR:

DZI:

EGR:

RARG:

GMX:

GSJ:

PVU:

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:

ADU:

AIP:

AHF:	112714566 112782349

LANG:

109330125

PCIN:

129285379

QSA:	O6P43_012670

FVE:

AANS:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:

MSYL:

PXB:

PCOX:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

MEAN:

JCU:

HBR:

MESC:

POP:	18103051 7477389

PEU:	105128003 105138888

PALZ:

118031368 118047282

PNZ:	133698153 133703821

JRE:

CILL:

CAVE:

AGLU:

QSU:

QLO:

TWL:

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107758995 107778070

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HAN:

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:

DLT:

BVG:

SOE:

CQI:	110693646 110706939

ATRI:

MOF:

NNU:

MING:

TSS:

PSOM:

OSA:

DOSA:

OBR:

OGL:

BDI:

ATS:

TDC:

TAES:

123061153 123138318 123182492

TUA:

125522994

LPER:

127327336

LRD:	124707388 124707418

SBI:

ZMA:

MFLO:

SITA:

SVS:

PVIR:

PHAI:

PAUA:

PDA:

EGU:

MUS:

ZOF:	122021532 122025676

DCT:

PEQ:

AOF:

MSIN:

ACAK:

NCOL:

ATR:

CJF:

PPP:

VCN:	VOLCADRAFT_119365

CVR:	CHLNCDRAFT_143502

APRO:

F751_5140

MIS:	MICPUN_63720

MPP:	MICPUCDRAFT_70260

DHA:	DEHA2F12738g

PIC:	PICST_47192

PGU:	PGUG_00910

SPAA:

SPAPADRAFT_157314

LEL:	PVL30_005471

LBG:	92209408(LODBEIA_P42120)

CAL:	CAALFM_C601470WA(CaO19.3437)

CTP:	CTRG_02843

COT:	CORT_0F03420

CDU:	CD36_61580

CLU:	CLUG_01120

CLUS:

A9F13_09g01782

CAUR:

CJI96_0003270

ASAU:

88176054(PUMCH_004994)

YLI:	2911860(YALI2_E00573g)

SLB:	AWJ20_3441

TET:	TTHERM_00509040

PTM:	GSPATT00009315001

NGR:	NAEGRDRAFT_65030

» show all

Reference

PMID:22002062

Authors

Okumoto K, Kametani Y, Fujiki Y

Title

Two proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid beta-oxidation in peroxisomal matrix.

Journal

J Biol Chem 286:44367-79 (2011)
DOI:10.1074/jbc.M111.285197

Sequence

[hsa:219743]

LinkDB

DBGET integrated database retrieval system