KEGG ORTHOLOGY: K23035

ORTHOLOGY: K23035

Entry

K23035                      KO

Symbol

TENT5D, FAM46D

Name

terminal nucleotidyltransferase 5D [EC:2.7.7.19]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis
    K23035  TENT5D, FAM46D; terminal nucleotidyltransferase 5D
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.19  polynucleotide adenylyltransferase
     K23035  TENT5D, FAM46D; terminal nucleotidyltransferase 5D
Messenger RNA biogenesis [BR:ko03019]
Eukaryotic type
  mRNA processing factors
   Other processing factors
    K23035  TENT5D, FAM46D; terminal nucleotidyltransferase 5D

Genes

HSA:	169966(TENT5D)

PTR:	740850(TENT5D)

PPS:	100992243(TENT5D)

GGO:	101124984(TENT5D)

PON:	100432746(TENT5D)

PPYG:

129024618(TENT5D)

NLE:	100579271(TENT5D)

HMH:	116465698(TENT5D)

SSYN:

129475946(TENT5D)

MCC:	708542(TENT5D)

MCF:	102134566(TENT5D)

MTHB:

126946248

MNI:	105464448(TENT5D)

CSAB:

103232255(FAM46D)

CATY:

105593779(FAM46D)

PANU:

101022683(TENT5D)

TGE:	112616046(TENT5D)

MLEU:

105539266(FAM46D)

RRO:	104681012(TENT5D)

RBB:	108524505(FAM46D)

TFN:	117077418(TENT5D)

PTEH:

111536479(TENT5D)

CANG:

105513275(FAM46D)

CJC:	100400284(TENT5D)

SBQ:	101036898(FAM46D)

CIMI:

108298256(TENT5D)

ANAN:

105719586(TENT5D)

CSYR:

103263273(FAM46D)

MMUR:

105866264(FAM46D)

PCOQ:

105826145(FAM46D)

OGA:	105887354(FAM46D)

MMU:	213449(Tent5d)

MCAL:

110286748(Tent5d)

MPAH:

110314178(Fam46d)

RNO:	302368(Tent5d)

MCOC:

116088188(Tent5d)

ANU:	117695281(Tent5d)

ASYL:

127675651(Tent5d)

MUN:	110543612(Tent5d)

CGE:	100755293(Tent5d)

MAUA:

101835665(Tent5d)

PROB:

127218268(Tent5d)

PLEU:

114704863(Tent5d)

MORG:

121442742 121445104

MFOT:

126492524

AAMP:

119805469(Tent5d)

NGI:	103725752(Fam46d)

HGL:	101699325(Fam46d)

CCAN:

109694736(Fam46d)

DORD:

105995198(Fam46d)

DSP:	122097670(Tent5d)

PLOP:

125343048(Tent5d)

NCAR:

124972626

MMMA:

107156079(Tent5d)

ITI:	101965058(Tent5d)

OCU:	100342078(TENT5D)

OPI:	101526594(TENT5D)

TUP:	102498049(FAM46D)

GVR:	103596297 103596487

CFA:	491983(TENT5D)

CLUD:

112671894(TENT5D)

VVP:	112911940(TENT5D)

VLG:	121482249(TENT5D)

NPO:	129517559(TENT5D)

AML:	100466946(TENT5D)

UMR:	103671963(TENT5D)

UAH:	113242111(TENT5D)

UAR:	123789774(TENT5D)

ELK:

111160940

MPUF:

101676417(FAM46D)

MNP:	132007491(TENT5D)

MLK:	131821472(TENT5D)

NVS:	122897122(TENT5D)

ORO:	101368684(FAM46D)

EJU:	114207564(TENT5D)

ZCA:	113930941(TENT5D)

MLX:	118025955(TENT5D)

NSU:	110579962(TENT5D)

LWW:	102728466(TENT5D)

FCA:	101091679(TENT5D)

PYU:	121025360(TENT5D)

PCOO:

112871146(TENT5D)

PBG:	122477468(TENT5D)

PVIV:

125157318(TENT5D)

LRUF:

124509163

LGF:	123594934 123594937 123594949

AJU:

113597488

PTG:	102972381(FAM46D)

PPAD:

109255079(FAM46D)

PUC:

125932210

HHV:	120226403(TENT5D)

BTA:	100124506(TENT5D)

BOM:	102278021(TENT5D)

BBUB:

102404271(TENT5D)

BBIS:

105003641(FAM46D)

CHX:	102183220(FAM46D)

OAS:	101120141(TENT5D)

BTAX:

128070344(TENT5D)

CSUM:

138071481(TENT5D)

ODA:	120881919(TENT5D)

CCAD:

122435123(TENT5D)

MREE:

136154477(TENT5D)

OVR:	110129105(TENT5D)

MBEZ:

129535105(TENT5D)

SSC:	100519527(FAM46D)

CFR:	102504077(TENT5D)

CBAI:

105065496(FAM46D)

CDK:	105093740(TENT5D)

VPC:	102526354(TENT5D)

BACU:

103016268

LVE:

103084852

OOR:	101281438(TENT5D)

LALB:

132513113(TENT5D)

DLE:	111178215(TENT5D)

PCAD:

102987845(TENT5D)

PSIU:

116747119(TENT5D)

NASI:

112395171(FAM46D)

ECB:	100072545(FAM46D)

EPZ:	103566213(TENT5D)

EAI:	106838368(TENT5D)

MYB:

102253602

MYD:	102766000(FAM46D)

MMYO:

118653294(TENT5D)

MLF:	102420180(FAM46D)

MDT:	132213867 132224402(TENT5D)

PKL:	118719953(TENT5D)

EFUS:

103298555(TENT5D)

MNA:	107531129(FAM46D) 107534517

DRO:	112317939(FAM46D)

SHON:

118996738(TENT5D)

AJM:	119057650(TENT5D)

PDIC:

114505415(TENT5D)

PHAS:

123824269(TENT5D)

MMF:	118621278 118636455(TENT5D)

PPAM:

129065338(TENT5D)

HAI:	109385678(FAM46D)

RFQ:	117029124(TENT5D)

PALE:

102883667(TENT5D)

PGIG:

120591850(TENT5D)

PVP:	105307109(FAM46D)

RAY:	107520763(TENT5D)

MJV:	108400631(TENT5D)

TOD:	119246647(TENT5D)

SARA:

101541092(FAM46D)

SFUM:

130032608(TENT5D)

LAV:	100654703(FAM46D)

TMU:

101344963

ETF:	101661137(TENT5D)

DNM:	101429397(FAM46D)

MDO:	100021033(FAM46D) 103091931

GAS:	123253569(TENT5D)

SHR:	100915636(TENT5D)

AFZ:

127542913

PCW:	110193024(FAM46D)

TVP:	118832943(TENT5D)

PBRV:

138141698(TENT5D)

GGA:	422282(FAM46D)

PCOC:

116229689

MGP:

100542077

CJO:

107312798

TPAI:

128076099(TENT5D)

LMUT:

125699870

NMEL:

110403224

APLA:

101799906(TENT5D)

ACYG:

106043000(TENT5D)

CATA:

118245609(TENT5D)

AFUL:

116494616(TENT5D)

TGU:	100221317(TENT5D)

LSR:	110474349(TENT5D)

SCAN:

103816440(TENT5D)

PMOA:

120508733(TENT5D)

OTC:	121331843(TENT5D)

PRUF:

121363158(TENT5D)

ATRC:

139597176(TENT5D)

GFR:	102036255(FAM46D)

FAB:	101816748(FAM46D)

OMA:	130253215(TENT5D)

PHI:	102114127(FAM46D)

PMAJ:

107203655(TENT5D)

CCAE:

111928577(FAM46D)

CCW:	104691295(TENT5D)

CBRC:

103622614(FAM46D)

ACOE:

138110185(TENT5D)

ETL:	114062064(TENT5D)

ZAB:	102068695(TENT5D)

ZLE:	135447645(TENT5D)

ACHL:

103797583

SVG:	106860331(FAM46D)

MMEA:

130582827(TENT5D)

HRT:	120764856 120765378

SATI:

136373239 136374625(TENT5D)

CCIC:

134050133(TENT5D)

FPG:	101916445(FAM46D)

FCH:	102059020(TENT5D)

CCRI:

104158592

NNT:

104401335

SHAB:

115612732(TENT5D)

ACUN:

113480226(TENT5D)

TALA:

104361631(TENT5D)

ACHC:

115333659(TENT5D)

HALD:

104319756

HLE:	104834800(FAM46D)

AGEN:

126050199

HHAR:

128153997(TENT5D)

GCL:

CSTI:

LDI:

MNB:

DPUB:

104296998(FAM46D)

PPUS:

135183779(TENT5D)

AVIT:

104271800

BRHI:

104501150

EGZ:	104135966(TENT5D)

NNI:	104012849(FAM46D)

PCRI:

104035150

PCAO:

104046579

PADL:

103919174(FAM46D)

AFOR:

103906165(FAM46D)

FGA:

104080186

GSTE:

104253034

CBOY:

140658746(TENT5D)

CLV:	102085881(FAM46D)

MUI:

PGUU:

PLET:

EHS:

CMAC:

CUCA:

104054287(TENT5D)

TEO:

104373507

BREG:

104635911

OHA:	104332242(FAM46D)

ACAR:

104530826

CPEA:

104387793(FAM46D)

CVF:	104283500(FAM46D)

RTD:	128915052(TENT5D)

CRID:

134521124(TENT5D)

AAM:

106494560

AROW:

112966324(TENT5D)

NPD:	112942306(TENT5D)

TGT:	104575042(FAM46D)

DNE:

112980801

SCAM:

104152340(FAM46D)

ASN:	102376045(TENT5D)

AMJ:	102569410(FAM46D)

CPOO:

109311070

GGN:

109300653

PSS:	102454240(TENT5D)

CMY:	102945162(TENT5D)

CCAY:

125642959(TENT5D)

DCC:

119861427

CPIC:

101939217(TENT5D)

TST:	117883372(TENT5D)

CABI:

116834696(TENT5D)

MRV:	120371307(TENT5D)

ACS:

100551774

ASAO:

132763000(TENT5D)

PVT:

110086638

SUND:

121936886(TENT5D)

PBI:

103056639

PMUR:

107289962(TENT5D)

CTIG:

120308471

TSR:

106551017

PGUT:

117675930

APRI:

131205134(TENT5D)

PTEX:

113437854

NSS:	113416586(TENT5D)

VKO:	123022072(TENT5D)

PMUA:

114589316(TENT5D)

PRAF:

128406151(TENT5D)

ZVI:

118093877

HCG:	128335532(TENT5D)

GJA:

107111934

STOW:

125442839(TENT5D)

EMC:	129341621(TENT5D)

XLA:	108698457(tent5d.L) 108700154(tent5d.S)

XTR:	100494671(tent5d)

NPR:

108802425

BBUF:

121009548(TENT5D)

BGAR:

122922419 122922420

PWL:	138264895(TENT5D)

MUO:	115474149(TENT5D)

GSH:	117360966(TENT5D)

CERY:

IFU:

TVC:

CGAR:

NGRA:

TRN:

CMAO:

CHAR:

105906306(tent5d)

SPIL:

AFB:

SPUL:

XCO:

CTUL:

NWH:

CSEM:

103391322(fam46d)

POV:

PPLT:

SDU:

XGL:

SBIA:

BPEC:

SJO:

SSCO:

GMH:	115552781(tent5d)

ELS:	105010192(tent5d)

SFM:	108920030 108925311(tent5d)

CCOG:

133123438 133132539

PSPA:

121295882 121318766

ARUT:

117412473 117430524

LCM:	102354445(FAM46D)

CMK:

RTP:

CPLA:

HOC:

LERI:

Reference

PMID:28931820

Authors

Mroczek S, Chlebowska J, Kulinski TM, Gewartowska O, Gruchota J, Cysewski D, Liudkovska V, Borsuk E, Nowis D, Dziembowski A

Title

The non-canonical poly(A) polymerase FAM46C acts as an onco-suppressor in multiple myeloma.

Journal

Nat Commun 8:619 (2017)
DOI:10.1038/s41467-017-00578-5

Sequence

[hsa:169966]

LinkDB

DBGET integrated database retrieval system