KEGG   ORTHOLOGY: K23178
Entry
K23178            Tight     KO                                     
Symbol
CYP71DD6
Name
eupatolide synthase [EC:1.14.14.169]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K23178  CYP71DD6; eupatolide synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.169  eupatolide synthase
     K23178  CYP71DD6; eupatolide synthase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP71 family
   K23178  CYP71DD6; eupatolide synthase
Genes
HAN: 110929409
Reference
PMID:29758164
  Authors
Frey M, Schmauder K, Pateraki I, Spring O
  Title
Biosynthesis of Eupatolide-A Metabolic Route for Sesquiterpene Lactone Formation Involving the P450 Enzyme CYP71DD6.
  Journal
ACS Chem Biol 13:1536-1543 (2018)
DOI:10.1021/acschembio.8b00126
Reference
PMID:21515683
  Authors
Ikezawa N, Gopfert JC, Nguyen DT, Kim SU, O'Maille PE, Spring O, Ro DK
  Title
Lettuce costunolide synthase (CYP71BL2) and its homolog (CYP71BL1) from sunflower catalyze distinct regio- and stereoselective hydroxylations in sesquiterpene lactone metabolism.
  Journal
J Biol Chem 286:21601-11 (2011)
DOI:10.1074/jbc.M110.216804
  Sequence
[han:110929409]
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