KEGG ORTHOLOGY: K23193

ORTHOLOGY: K23193

Entry

K23193                      KO

Symbol

MYT1L

Name

myelin transcription factor 1-like protein

Disease

H00773

Autosomal dominant intellectual developmental disorder

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K23193  MYT1L; myelin transcription factor 1-like protein
   03036 Chromosome and associated proteins
    K23193  MYT1L; myelin transcription factor 1-like protein
Transcription factors [BR:ko03000]
Eukaryotic type
  Zinc finger
   Cys2HisCys zinc factors
    K23193  MYT1L; myelin transcription factor 1-like protein
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Histone modification proteins
   HDAC complexes
    Other HDAC associated proteins
     K23193  MYT1L; myelin transcription factor 1-like protein

Genes

HSA:	23040(MYT1L)

PTR:	458998(MYT1L)

PPS:	100971174(MYT1L)

GGO:	101127445(MYT1L)

PON:	100454385(MYT1L)

PPYG:

129030325(MYT1L)

NLE:	100600787(MYT1L)

HMH:	116480143(MYT1L)

SSYN:

129468322(MYT1L)

MCC:	114675510 706914(MYT1L)

MCF:	102122438(MYT1L)

MTHB:

126933454

MNI:	105497564(MYT1L)

CSAB:

103220942(MYT1L)

CATY:

105587593(MYT1L)

PANU:

101004144(MYT1L)

TGE:	112605124(MYT1L)

MLEU:

105546348(MYT1L)

RRO:	104680244(MYT1L)

RBB:	108520806(MYT1L)

TFN:	117062797(MYT1L)

PTEH:

111526758(MYT1L)

CANG:

105525361(MYT1L)

CJC:	100386594(MYT1L)

SBQ:	101029514(MYT1L)

CIMI:

108292907(MYT1L)

ANAN:

105726758(MYT1L)

CSYR:

103259137(MYT1L)

MMUR:

105870507(MYT1L)

LCAT:

123636563(MYT1L)

PCOQ:

105824645(MYT1L)

OGA:	100951489(MYT1L)

MMU:	17933(Myt1l)

MCAL:

110307424(Myt1l)

MPAH:

110324468(Myt1l)

RNO:	116668(Myt1l)

MCOC:

116079843(Myt1l)

ANU:	117716903(Myt1l)

ASYL:

127687413(Myt1l)

MUN:	110561243(Myt1l)

CGE:	100750480(Myt1l)

MAUA:

101837813(Myt1l)

PROB:

127234375(Myt1l)

PLEU:

114702650(Myt1l)

MORG:

121432342(Myt1l)

MFOT:

126491110

AAMP:

119806941(Myt1l)

NGI:	103747654(Myt1l)

HGL:	101717418(Myt1l)

CPOC:

100731813(Myt1l)

CCAN:

109698841(Myt1l)

DORD:

105995176(Myt1l)

DSP:	122096403(Myt1l)

DMER:

138822114(Myt1l)

PLOP:

125355911(Myt1l)

NCAR:

124963137

MMMA:

107137533(Myt1l)

ITI:	101962957(Myt1l)

OCU:

100338864

OPI:	101536168(MYT1L)

TUP:	102503108(MYT1L)

GVR:

103606923

CFA:	482954(MYT1L)

CLUD:

112664919(MYT1L)

VVP:	112927751(MYT1L)

VLG:	121490412(MYT1L)

NPO:	129510951(MYT1L)

AML:	100481931(MYT1L)

UMR:	103659102(MYT1L)

UAH:	113269107(MYT1L)

UAR:	123786598(MYT1L)

ELK:

111154049

LLV:

125109280

MPUF:

101689368(MYT1L)

MNP:	132021094(MYT1L)

MLK:	131807438(MYT1L)

NVS:	122915353(MYT1L)

ORO:	101385094(MYT1L)

EJU:	114205917(MYT1L)

ZCA:	113938176(MYT1L)

MLX:	118007281 118007339

LWW:

102735475

FCA:	101091863(MYT1L)

PYU:	121044606(MYT1L)

PCOO:

112864371(MYT1L)

PBG:	122497512(MYT1L)

PVIV:

125158321(MYT1L)

LRUF:

124525758

LGF:	123581685(MYT1L)

AJU:

106970830

PTG:	102969485(MYT1L)

PPAD:

109258732(MYT1L)

PUC:

125937364

PLEZ:

122216667(MYT1L)

HHV:	120247920(MYT1L)

BTA:	537684(MYT1L)

BOM:	102271489(MYT1L)

BBUB:

102407634(MYT1L)

BBIS:

104994788(MYT1L)

CHX:	102182410(MYT1L)

OAS:	101113208(MYT1L)

BTAX:

128052022(MYT1L)

CSUM:

138081017(MYT1L)

ODA:	120864410(MYT1L)

CCAD:

122431675(MYT1L)

MREE:

136176704(MYT1L)

OVR:	110141225(MYT1L)

MBEZ:

129557444(MYT1L)

SSC:	100626723(MYT1L)

CFR:	102509841(MYT1L)

CBAI:

105075312(MYT1L)

CDK:	105094017(MYT1L)

VPC:	102532581(MYT1L)

BACU:

103019466(MYT1L)

BMUS:

118906410(MYT1L)

LVE:	103091445(MYT1L)

OOR:	101277354(MYT1L)

LALB:

132531103(MYT1L)

GMF:	115846065(MYT1L)

DLE:	111167987(MYT1L)

PCAD:

102992803(MYT1L)

PSIU:

116764336(MYT1L)

PPHC:

136134027(MYT1L)

NASI:

112407575(MYT1L)

ECB:	100057365(MYT1L)

EPZ:	103558901(MYT1L)

EAI:	106831424(MYT1L)

MYB:	102249426(MYT1L)

MYD:	102752653(MYT1L)

MMYO:

118669323(MYT1L)

MLF:	102436430(MYT1L)

MDT:	132213678(MYT1L)

MYUM:

139019662(MYT1L)

PKL:	118714841(MYT1L)

EFUS:

103305613(MYT1L)

MNA:	107526680(MYT1L)

DRO:	112298061(MYT1L)

SHON:

118988730(MYT1L)

AJM:	119054023(MYT1L)

PDIC:

114498751(MYT1L)

PHAS:

123822569(MYT1L)

MMF:	118630758(MYT1L)

PPAM:

129067805(MYT1L)

HAI:	109384721(MYT1L)

RFQ:	117033052(MYT1L)

PALE:

102895141(MYT1L)

PGIG:

120596521(MYT1L)

PVP:	105306143(MYT1L)

RAY:	107516253(MYT1L)

TOD:	119259596(MYT1L)

SARA:

101544304(MYT1L)

SFUM:

130036353(MYT1L)

SETR:

126024468(MYT1L)

LAV:	100659255(MYT1L)

TMU:

101356294

ETF:	101660580(MYT1L)

DNM:	101445618(MYT1L)

MDO:	100028451(MYT1L)

GAS:	123234930(MYT1L)

SHR:	100935091(MYT1L)

AFZ:

127548581

PCW:	110193838(MYT1L)

TVP:	118843835(MYT1L)

PBRV:

138177494(MYT1L)

OAA:	100080397(MYT1L)

TACU:

119950168(MYT1L)

GGA:	421915(MYT1L)

PCOC:

116240663(MYT1L)

MGP:

100548026

CJO:	107312174(MYT1L)

TPAI:

128087512(MYT1L)

LMUT:

125689476(MYT1L)

NMEL:

110397103(MYT1L)

APLA:

101797407(MYT1L)

ACYG:

106030687(MYT1L)

CATA:

118246125(MYT1L)

AFUL:

116488160(MYT1L)

TGU:	100227948(MYT1L)

LSR:	110482169(MYT1L)

SCAN:

103820247(MYT1L)

PMOA:

120505301(MYT1L)

OTC:	121344498(MYT1L)

PRUF:

121359144(MYT1L)

ATRC:

139596838(MYT1L)

GFR:	102034746(MYT1L)

FAB:	101811323(MYT1L)

OMA:	130251667(MYT1L)

PHI:	102109953(MYT1L)

PMAJ:

107201831(MYT1L)

CCAE:

111925920(MYT1L)

CCW:	104685469(MYT1L)

CBRC:

103622762(MYT1L)

ACOE:

138108614(MYT1L)

ETL:	114063741(MYT1L)

ZAB:	102066598(MYT1L)

ZLE:	135445337(MYT1L)

ACHL:

103811405(MYT1L)

SVG:	106849120(MYT1L)

MMEA:

130576853(MYT1L)

HRT:	120750316(MYT1L)

SATI:

136358815(MYT1L)

CCIC:

134041641(MYT1L)

FPG:	101913097(MYT1L)

FCH:	102059891(MYT1L)

CCRI:

104157304(MYT1L)

NNT:	104402820(MYT1L)

SHAB:

115609433(MYT1L)

ACUN:

113478033(MYT1L)

TALA:

104360703(MYT1L)

ACHC:

115351152(MYT1L)

HALD:

104317840(MYT1L)

HLE:	104831260(MYT1L)

AGEN:

126046502

HHAR:

128151906(MYT1L)

GCL:

127014369

CSTI:

104561524(MYT1L)

LDI:	104350640(MYT1L)

MNB:

103770598

DPUB:

104301670(MYT1L)

PPUS:

135176694(MYT1L)

AVIT:

104266988

EGZ:	104122173(MYT1L)

NNI:	104013831(MYT1L)

PCRI:

104038929(MYT1L)

PCAO:

104042550(MYT1L)

PADL:

103921350(MYT1L)

AFOR:

103895873(MYT1L)

FGA:	104072726(MYT1L)

GSTE:

104262332(MYT1L)

CBOY:

140649944(MYT1L)

CLV:	102095774(MYT1L)

CNIC:

135986549(MYT1L)

MUI:

104536411

PLET:

104628682(MYT1L)

EHS:

104511716

CMAC:

104476948

CUCA:

104064873(MYT1L)

TEO:

104381856

BREG:

104641170(MYT1L)

OHA:	104330251(MYT1L)

ACAR:

104531044(MYT1L)

CPEA:

104390077(MYT1L)

CVF:	104289029(MYT1L)

RTD:	128906999(MYT1L)

CRID:

134513526(MYT1L)

AAM:	106492990(MYT1L)

AROW:

112973094(MYT1L)

NPD:	112945443(MYT1L)

TGT:	104564953(MYT1L)

DNE:	112987124(MYT1L)

SCAM:

104143493(MYT1L)

ASN:	102374230(MYT1L)

AMJ:	102567152(MYT1L)

CPOO:

109311686(MYT1L)

GGN:	109300042(MYT1L)

PSS:	102446464(MYT1L)

CMY:	102939842(MYT1L)

CCAY:

125634524(MYT1L)

DCC:	119853681(MYT1L)

CPIC:

101932585(MYT1L)

TST:	117875265(MYT1L)

CABI:

116831248(MYT1L)

MRV:	120401614(MYT1L)

ACS:	100559433(myt1l)

ASAO:

132760693(MYT1L)

PVT:	110073422(MYT1L)

SUND:

121935761(MYT1L)

PBI:	103048091 103055700

PMUR:

107288272(MYT1L)

CTIG:

120310083(MYT1L)

TSR:

106545430

PGUT:

117674181(MYT1L)

PCAE:

139325271(MYT1L)

APRI:

131195684(MYT1L)

PTEX:

113455237(MYT1L)

NSS:	113410559(MYT1L)

VKO:	123017697(MYT1L)

PMUA:

114593756(MYT1L)

PRAF:

128410064(MYT1L)

ZVI:	118082423(MYT1L)

HCG:	128340642(MYT1L)

GJA:	107121359(MYT1L)

STOW:

125433457(MYT1L)

EMC:	129329716(MYT1L)

XLA:	108717166 108718228

XTR:	100494385(myt1l)

NPR:	108789265(MYT1L)

RTEM:

120936384(MYT1L)

ACAT:

141139398(MYT1L)

BBUF:

120999957(MYT1L)

BGAR:

122934966(MYT1L)

DTC:	141083758(MYT1L)

PWL:	138296588(MYT1L)

MUO:	115467176(MYT1L)

GSH:	117358222(MYT1L)

DRE:	100332876(myt1lb) 559505(myt1la)

SRX:	107726464 107732629 107753351 107758718

SANH:

107668232 107684244(myt1l) 107687836 107693230

SGH:	107549112 107570256(myt1l) 107589778 107601686

CCAR:

109044879 109107687 109108462 122140192

CAUA:

113037908 113060381 113062800 113116965

CGIB:

127938675 127976282 127984593 128031376

PTET:

122362012 122362020(myt1lb)

LROH:

127179710(myt1lb) 127182967(myt1la)

GRF:	141283147(myt1la) 141295418(myt1lb)

OMC:	131523513(myt1lb) 131527605(myt1la)

PPRM:

120462358(myt1lb) 120494092(myt1la)

RKG:	130075476(myt1la) 130088865(myt1lb)

MAMB:

125268263(myt1lb) 125278061(myt1la)

CIDE:

127498781 127502779

CERY:

137007101(myt1lb) 137018434(myt1la)

MASI:

127410153 127410931 127415759 127455353

TROS:

130560211(myt1lb) 130565603(myt1la)

TDW:	130434456(myt1la) 130436478(myt1lb)

MANU:

129417568(myt1lb) 129428927(myt1la)

PDAB:

135738047(myt1la) 135777857(myt1lb)

IPU:	108257609(myt1la) 108270483(myt1lb)

IFU:	128601115(myt1la) 128612338(myt1lb)

PHYP:

113532376 113538932

SMEO:

124377132(myt1la) 124390167(myt1lb)

TFD:	113655659(myt1la) 113659652(myt1lb)

TVC:	132843214(myt1la) 132852679(myt1lb)

CGAR:

128515376(myt1la) 128535965(myt1lb)

NGRA:

132883869(myt1la) 132894611(myt1lb)

TRN:	134320732(myt1la) 134324843(myt1lb)

AMEX:

103038403(myt1lb) 103042546(myt1la)

CMAO:

118815619(myt1la) 118823650(myt1lb)

EEE:	113570550 113580666

CHAR:

105889788(myt1la) 105893141(myt1lb)

SPIL:

134067627(myt1lb) 134098280

TRU:	101062858 101064387

TFS:	130516264(myt1la) 130539654(myt1lb)

TNG:	GSTEN00020252G001

LCO:	104929311(myt1l) 104930522

NCC:	104961365(myt1l)

TBEN:

117477158(myt1la) 117477809(myt1lb)

CGOB:

115003493 115027308(myt1l)

PGEO:

117468148(myt1lb)

GACU:

117533528 117549978(myt1lb) 117551483

EMAC:

134877378(myt1la) 134880972(myt1lb)

ELY:	117267169(myt1lb) 117270757(myt1la)

EFO:	125897321(myt1la) 125900471(myt1lb)

PLEP:

121953668(myt1lb) 121955416(myt1la)

SLUC:

116055835(myt1la) 116065717(myt1lb)

ECRA:

117935657(myt1lb) 117960996(myt1la)

ESP:	116669954(myt1l) 116706098

PFLV:

114546853(myt1l) 114573253

GAT:	120808407(myt1la) 120832953

PPUG:

119194596(myt1la) 119227704(myt1lb)

AFB:	129103753(myt1lb) 129107062(myt1la)

CLUM:

117727766(myt1la) 117751531(myt1lb)

PSWI:

130201632(myt1lb) 130202987

CANA:

137801317 137803296(myt1lb)

CVE:	137877740(myt1lb)

MSAM:

119908689(myt1la) 119911001(myt1lb)

SCHU:

122861688(myt1lb) 122863027(myt1la)

CUD:	121520905(myt1la) 121526351(myt1lb)

SPUL:

138590881(myt1lb) 138612509(myt1la)

LMIX:

132984659(myt1la) 132993443(myt1lb)

ALAT:

119005075(myt1lb) 119011989(myt1la)

ASTR:

137610785(myt1lb) 137613340(myt1la)

MZE:	101477623(myt1l) 101482286

ONL:	100694947 100697199(myt1l)

OAU:	116327975(myt1lb) 116329564(myt1la)

OLA:	101162331 101166026

OML:	112145115(myt1lb) 112158343(myt1la)

CSAI:

133462500(myt1lb) 133464399(myt1la)

XMA:	102225935(myt1l) 102233291

XCO:	114134328(myt1l) 114158952

XHE:	116708955(myt1l) 116733885

PRET:

103457057 103458657(myt1l)

PFOR:

103155343 103156418

PLAI:

106935564 106958095

PMEI:

106929104

GAF:	122825534(myt1la) 122845640(myt1lb)

PPRL:

129353671(myt1la) 129365238(myt1lb)

CVG:	107088847(myt1l) 107098173

CTUL:

119788407(myt1lb) 119796705(myt1la)

GMU:	124855208(myt1lb) 124882054(myt1la)

NFU:	107378206 107391712(myt1l)

KMR:	108245095(myt1lb) 108249106(myt1la)

ALIM:

106518989 106527674(myt1l)

NWH:	119417990 119427374(myt1lb)

AOCE:

111566939(myt1la) 111577404(myt1lb)

EJA:	138205150(myt1lb) 138215364(myt1la)

BFRE:

138614283(myt1la) 138632126(myt1lb)

MCEP:

124998665(myt1la) 125023934(myt1lb)

CSEM:

103381328 103398428

POV:	109627879(myt1l) 109644355 109644525

SSEN:

122762832 122762913 122782711(myt1lb)

SSOE:

131443478(myt1la) 131444778(myt1lb)

HHIP:

117756461(myt1lb) 117758264(myt1la)

HSP:	118099693(myt1la) 118117048(myt1lb)

PPLT:

128450356(myt1lb) 128459870(myt1la)

SMAU:

118286626(myt1lb) 118290507(myt1la)

LCF:	108872451(myt1la) 108896117

SDU:	111226106 111231713

SLAL:

111645529(myt1l) 111656013

XGL:	120789326(myt1la) 120795413(myt1lb)

HCQ:	109516761 109519967(myt1l)

SSCV:

125980884(myt1lb) 125989776(myt1la)

SBIA:

133496485(myt1la) 133512939(myt1lb)

PEE:	133412579(myt1lb) 133417120(myt1la)

PTAO:

133468494(myt1la) 133487824(myt1lb)

BPEC:

110155345(myt1l) 110173247

ENY:	140359811 140370873(myt1lb)

MALB:

109952091 109964935(myt1l)

BSPL:

114848266(myt1lb) 114849203(myt1la)

SJO:	128374988(myt1lb) 128377505(myt1la)

SSCO:

133998025(myt1la) 134000467(myt1lb)

GMH:	115534258 115544254

SASA:

106571614 106573019 106608144 106610767(myt1l)

STRU:

115162486 115164640 115172775 115174556

OTW:	112217993 112251514(myt1la) 112256542 112261970

OMY:	110498066 110505383 110521081 110529817(myt1la)

OGO:	123990946(myt1la) 123995338 124001193 124046335

ONE:	115122210 115138371

OKI:	109866688 109893784 109900922 109904515

OKE:	118362335 118369100 118392408 118397713(myt1la)

OMM:	135505776(myt1la) 135508360 135526018 135557854

OCLA:

139375333 139383547 139407341 139415307

SALP:

111954302 111963138 111968857 111972546 112068667

SNH:	120019530 120023328 120024476(myt1la) 120059778

CCLU:

121539147 121545045 121548600 121552908(myt1la)

ELS:	105015756(myt1l) 105024818

OEP:	134024972(myt1la) 134026842(myt1lb)

SFM:	108922680(myt1l) 108929220

PKI:	111841805 111850687

AANG:

118225860(myt1lb) 118230046(myt1la)

AROT:

135254166(myt1lb) 135257241(myt1la)

CCOG:

133128528(myt1la) 133137059(myt1lb)

LOC:	102691457(myt1l)

PSPA:

121315362 121317554

ARUT:

117403113 117411410

PSEX:

120526013

LCM:	102353370(MYT1L)

CMK:

RTP:

CPLA:

HOC:

LERI:

HAKA:

PMRN:

116941732 116946650(MYT1L) 116951355

LRJ:	133344089 133347466 133353050

BFO:

BBEL:

AJJ:

AFIL:

PFLL:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ011292 CpipJ_CPIJ018573

CPII:

MPHA:

ACEP:

VEM:

HST:

PGC:

DMK:

PJA:

HAME:

PCLA:

PTRU:

HAZT:

LSM:

DSV:

RSAN:

VDE:

VJA:	111272356 111273227

CSCU:

111620989 111639153

PTEP:

107443893

SDM:	118184744 118187366

PCAN:

BGT:

CRG:

PMAX:

XEN:

Reference

PMID:28470180

Authors

Kepa A, Martinez Medina L, Erk S, Srivastava DP, Fernandes A, Toro R, Levi S, Ruggeri B, Fernandes C, Degenhardt F, Witt SH, Meyer-Lindenberg A, Poncer JC, Martinot JL, Paillere Martinot ML, Muller CP, Heinz A, Walter H, Schumann G, Desrivieres S

Title

Associations of the Intellectual Disability Gene MYT1L with Helix-Loop-Helix Gene Expression, Hippocampus Volume and Hippocampus Activation During Memory Retrieval.

Journal

Neuropsychopharmacology 42:2516-2526 (2017)
DOI:10.1038/npp.2017.91

Sequence

[hsa:23040]

LinkDB

DBGET integrated database retrieval system