KEGG ORTHOLOGY: K23462

ORTHOLOGY: K23462

Entry

K23462                      KO

Symbol

tgnA

Name

flavin-dependent trigonelline monooxygenase, reductase component [EC:1.5.1.36]

Pathway

map00740

Riboflavin metabolism

map01100

Metabolic pathways

Reaction

R05705

FMNH2:NAD+ oxidoreductase

R09748

FADH2:NAD+ oxidoreductase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00740 Riboflavin metabolism
    K23462  tgnA; flavin-dependent trigonelline monooxygenase, reductase component
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.36  flavin reductase (NADH)
     K23462  tgnA; flavin-dependent trigonelline monooxygenase, reductase component

Other DBs

COG:

COG1853

GO:

0036382

Genes

EAE:

EAE_03415

SMAR:

SM39_1852

SMAF:

D781_1304

SRZ:	AXX16_3791

SERM:

CLM71_06370

SFJ:	SAMEA4384070_3301(C1-hpah)

SOF:	NCTC11214_04442(C1-hpah)

SRHZ:

FO014_03475

SSAR:

SSARUM_002326

SERT:

TAN611_1365(tgnA)

CARU:

P0E69_22670

NIG:	C1N62_18680

PANT:

PSNIH1_p01110

PER:	LAC65_17325

KPIE:

N5580_20210

PVC:	G3341_16335

XCZ:	EBN15_14945

PWI:	MWN52_11410

PRE:	PCA10_27140

PMUI:

G4G71_18515

PNT:	G5B91_20005

PPW:	PputW619_2289

PFV:	Psefu_1103

PVR:	PverR02_11520

PSNC:

PFOU:

PBAB:

PALI:

PSYP:

ABY:

ABC:	ACICU_01362

ABN:

AB57_1555

ABB:	ABBFA_02133(hpah_3)

ABX:

ABK1_1810

ABZ:	ABZJ_01524

ABR:	ABTJ_02346

ABD:	ABTW07_1531

ABH:

M3Q_1722

ABJ:	BJAB07104_01525

ABAJ:

BJAB0868_01477

ABAZ:

P795_10580

ABK:	LX00_06725

ABAU:

IX87_03655

ABW:	BL01_01960

ABAN:

ABUW_2498

ACC:	BDGL_000704(ntaB)

ACI:

ASOL:

AGU:

ABER:

AVZ:	HWI77_18530

AVIV:

LF296_05385

ACOT:

QLH32_00520

ACIZ:

TOL5_09650(ntaB)

ACZQ:

SC192_07215

HAA:	A5892_15955

MMW:	Mmwyl1_2478

MME:	Marme_2435

MRHI:

KDW99_07395

MATH:

THO17_18840

TSN:	W908_00225

THIN:

CRN91_01160

PSE:

NH8B_2546

BPS:

BPSL1645

BPM:	BURPS1710b_2215(ntaB)

BPR:	GBP346_A2132

BPSE:

BPSM:

BPSU:

BPSD:

BPZ:	BP1026B_I1590

BPK:

BPSH:

BPSA:

BPSO:

BUT:

BAM:

BMJ:	BMULJ_05410 BMULJ_05415

BMU:	Bmul_6116 Bmul_6121

BMK:	DM80_6570 DM80_6575

BMUL:

NP80_5323 NP80_5328

BCON:

NL30_35585

BPSL:

WS57_00575 WS57_00600

BUG:	BC1001_4399 BC1001_5788

BGD:	bgla_2g20760

BGO:

BM43_5769

BUI:	AX768_12690

BURK:

DM992_17900 DM992_17925

BPX:	BUPH_00976 BUPH_06008

BCAI:

K788_0007443

PSPW:

BJG93_31305 BJG93_31365

PHS:	C2L64_38005

PTER:

C2L65_33980

PCAF:

DSC91_007526

PTRO:

G5S35_25775 G5S35_25835

PACP:

FAZ97_25760 FAZ97_25790

PACS:

FAZ98_23330 FAZ98_23390

PDIO:

PDMSB3_2781.1

PSAA:

QEN71_11660 QEN71_32550

PHUN:

U0042_09470

PPK:	U875_08105

PPNO:

DA70_00815

PPNM:

LV28_05500

PRB:	X636_01520

PSPU:

NA29_09695

PVE:	UC34_05140

PCOM:

NTU39_19945

CABA:

SBC2_49970 SBC2_65470(tgnA)

TVL:	FAZ95_20755

AON:	DEH84_18615

MLN:	A9174_35345

MCI:	Mesci_6249 Mesci_6274

MCIC:

A4R28_31950

MOP:	Mesop_5976

MAM:	Mesau_02855

MAMO:

A6B35_23750 A6B35_30565

MESW:

A9K65_034090

MESP:

C1M53_05785

MJR:	EB229_35220

MERD:

MMEI:

MESJ:

MES:

PHT:	BLM14_24730

SME:

SMa0793

SMK:	Sinme_6373

SMQ:	SinmeB_6002

SMX:	SM11_pC1147

SMI:	BN406_04216

SMEG:

SMEL:

SMER:

SMD:

RHI:	NGR_b17040

SFH:	SFHH103_05522

SFD:	USDA257_c12480(ntaB)

SIX:	BSY16_4968 BSY16_5837

SAME:

SAMCFNEI73_pC1124(ntaB)

SINO:

SS05631_b56850

ESJ:	SJ05684_b41450

EAK:	EKH55_4058

ENU:	PYH37_001925

SKM:	PZL22_006124

EAH:	FA04_30140

ECAA:

J3R84_28855 J3R84_32025

EAW:	ACEP9W_29870

ATU:	Atu4239 Atu5229(ntaB)

AGR:	AGROH133_12288

ATF:	Ach5_36060

ARUI:

G6M88_22950

AVV:	RvVAT039_42650

AVF:	RvVAR031_35190

ALEG:

CFBP4996_18960

AGRC:

GSF67_18115

AVI:

Avi_6086

RET:	RHE_PC00024 RHE_PF00197

REC:	RHECIAT_PC0000391

REL:	REMIM1_PB00026

REP:	IE4803_PD00027

REI:	IE4771_PE00026

RLE:

pRL100244

RLT:	Rleg2_5504 Rleg2_5585

RLG:

Rleg_6548

RLB:	RLEG3_01635

RLU:	RLEG12_04940 RLEG12_08650

RGA:	RGR602_PC01855

RHN:	AMJ98_PB00027

RPHA:

AMC79_PA00027 AMC79_PD00424

RHX:	AMK02_PB00026

RHK:	Kim5_PD00027

REZ:	AMJ99_PA00027

RJG:	CCGE525_22755

RHR:	CKA34_31430

RAD:	CO657_34940

RII:	FFM53_035070

RHID:

FFM81_022960

RBQ:	J2J99_32700

RLN:	J0663_28315

RBAN:

J2J98_27845

RRG:	J3P73_31815

RLS:	HB780_04475

RAW:	NE851_00185

RLW:	RlegWSM1455_33015

ARA:

Arad_9726

ARO:	B0909_19520

RBW:	RLCC275e_31950

RIF:	U5G49_006671

RHIZ:

RHIB:

RHIP:

RHIK:

SHZ:

SOJ:	K6301_24035

SSUM:

Q9314_24395

OCC:	KMS41_24015

BVV:	BHK69_08815 BHK69_09810

BVES:

QO058_20970

BOP:	AXW83_06275

BOI:	BLM15_04965

BOF:	FQV39_06500

BOW:	NWE53_05315

BOSE:

RMR04_15390 RMR04_25080

LNE:	FZC33_05935

APOL:

K9D25_15530

MOG:	MMB17_18935

JAV:	OXU80_27040

NOH:	G5V57_01330

PSF:

LABR:

LABP:

SIL:

RUA:	D1823_06485

RUT:	FIU92_06550(C1-hpah)

RUY:	NOR97_06500

RPON:

G3256_02880

RFU:	ROLI_027430

PGA:	PGA1_c21090

PGL:	PGA2_c19940

PGD:

Gal_01293

PHP:	PhaeoP97_01840

PPIC:

PhaeoP14_01920

PHQ:	D1820_06005

PHAE:

N1037_01755

LMD:	METH_21765

LEJ:	ETW24_21335

LAQU:

R2C4_00330

LEV:	ETW23_23040

LCAE:

MALG:

SULZ:

SULI:

RID:	RIdsm_01101(hsaB_1) RIdsm_01320(ntaB_2)

ROH:	FIU89_05055(hsaB)

RPEL:

N7U68_00170 N7U68_04010 N7U68_14180

RRL:	RZS32_010275

LALG:

LentiSH36_02584

ASCA:

QEZ52_05715

FYT:	QF092_05650

PSAP:

JHX88_11110

PFIS:

JHX87_02795

DON:	BSK21_15720

MALC:

QQG91_08385

RBZ:	B9057_15970

TLB:	RPE78_13835

GEH:	HYN69_06885

GFU:	KM031_06910 KM031_18020

TAW:	EI545_17520

SEDI:

EBB79_11390 EBB79_22505

PPSO:

QPJ95_16170

PSEB:

EOK75_06705

PAED:

G5B38_01250 G5B38_09825

HDH:	G5B40_19060

FAP:	GR316_12530

ACRO:

K3J57_09930

MANH:

LA6_003125(hsaB)

HBA:

Hbal_2540

SAND:

H3309_14910

AMV:	ACMV_P1_02500

AZL:	AZL_a09440

AOZ:	HUE56_08255

AZS:	E6C72_20425

AZP:	E6C67_13465

DEX:	HWD60_12350

THAC:

CSC3H3_22835

PFER:

IRI77_01885

ACUR:

JZ785_10300

SGZ:	C0216_07700

SVN:	CP980_10875

SGLY:

P8A20_36490

STIC:

DRB89_16055

STRQ:

CGL27_42620

LRP:	MUN76_11020

DERM:

AACD:

CATI:

Reference

PMID:29686076

Authors

Perchat N, Saaidi PL, Darii E, Pelle C, Petit JL, Besnard-Gonnet M, de Berardinis V, Dupont M, Gimbernat A, Salanoubat M, Fischer C, Perret A

Title

Elucidation of the trigonelline degradation pathway reveals previously undescribed enzymes and metabolites.

Journal

Proc Natl Acad Sci U S A 115:E4358-E4367 (2018)
DOI:10.1073/pnas.1722368115

Sequence

[aci:ACIAD2544]

LinkDB

DBGET integrated database retrieval system